FRANCISELLA TULARENSIS – A DECEITFUL PATHOGEN

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VOLUME 56 , ISSUE 2 (April 2017) > List of articles

FRANCISELLA TULARENSIS – A DECEITFUL PATHOGEN

Kamila Formińska * / Aleksandra Anna Zasada

Keywords : F. tularensis, tularemia, czynniki zjadliwości,   F. tularensis, tularemia, virulence factors

Citation Information : Postępy Mikrobiologii - Advancements of Microbiology. Volume 56, Issue 2, Pages 187-195, DOI: https://doi.org/10.21307/PM-2017.56.2.187

License : (CC BY-NC-ND 4.0)

Published Online: 21-May-2019

ARTICLE

ABSTRACT

Francisella tularensis is an intracellular bacterial pathogen which causes a potentially lethal disease named tularemia. Some studies have been conducted to describe and identify the virulence factors of F. tularensis. This pathogen is able to infect a variety of cells of various hosts, including wild animals, especially rabbits, hares and rodents, and humans. This may suggest that genes of F. tularensis must adapt to many different intraorganismal environments. Still, little is known about the virulence of F. tularensis. This review focuses on the main virulence factors of F. tularensis which are involved in intramacrophage replication and its survival mechanisms during infection.

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