AMOEBAE OF THE GENUS ACANTHAMOEBA – PATHOLOGICAL AGENTS IN HUMANS

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VOLUME 56 , ISSUE 4 (April 2017) > List of articles

AMOEBAE OF THE GENUS ACANTHAMOEBA – PATHOLOGICAL AGENTS IN HUMANS

Marcin Padzik * / Edyta B. Hendiger / Lidia Chomicz / Jacek P. Szaflik

Keywords : Acanthamoeba keratitits, Acanthamoeba spp., cutaneous acanthamebiasis, granulomatous amebic encephalitis

Citation Information : Postępy Mikrobiologii - Advancements of Microbiology. Volume 56, Issue 4, Pages 429-439, DOI: https://doi.org/10.21307/PM-2017.56.4.429

License : (CC BY-NC-ND 4.0)

Published Online: 22-May-2019

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ABSTRACT

Free living, cosmopolitan amoebae of the genus Acanthamoeba present a serious risk to human health. As facultative human parasites, these amoebae may cause health and life-threatening diseases, such as Acanthamoeba keratitis (AK), granulomatous amoebic encephalitis (GAE) and cutaneous acanthamebiasis. AK is a severe, vision-threatening cornea infection with non-specific symptoms and course. GAE is a unique central nervous system disease, almost always leading to death. Cutaneous acanthamebiasis is most common in patients with AIDS. The pathogenesis and pathophysiology of the diseases is still incompletely understood, therefore no definitive effective therapy is currently available. Prevention is very difficult due to Acanthamoeba ubiquity and resistance. Further studies on effective solutions for the prevention and treatment of Acanthamoeba infections are needed.

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