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Acta Neurobiologiae Experimentalis

Nencki Institute of Experimental Biology

Polish Neuroscience Society

Subject: Behavioral Sciences , Biomedical Sciences & Nutrition , Life Sciences , Medicine , Neurosciences

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ISSN: 0065-1400
eISSN: 1689-0035

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Selective neuronal death following exposure to methylenedioxypyrovalerone is accompanied by an inhibition of NMDA receptor NR2B subunit expression
Selective neuronal death following exposure to methylenedioxypyrovalerone is accompanied by an inhibition of NMDA receptor NR2B subunit expression
Neuroprotective effects of lipopolysaccharide and naltrexone co-preconditioning in the photothrombotic model of unilateral selective hippocampal ischemia in rat
Neuroprotective effects of lipopolysaccharide and naltrexone co-preconditioning in the photothrombotic model of unilateral selective hippocampal ischemia in rat
Differences in spatio-temporal distribution of the visual P3b event-related potential between young men and women
Differences in spatio-temporal distribution of the visual P3b event-related potential between young men and women
Fos immunoreactivity in the intermediolateral nucleus induced by tendon vibration of the m. triceps surae in rats pretreated with a nitric oxide blocker or precursor
Fos immunoreactivity in the intermediolateral nucleus induced by tendon vibration of the m. triceps surae in rats pretreated with a nitric oxide blocker or precursor

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Volume 80 (2020)
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Volume 76 (2016)
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VOLUME 76 , ISSUE 2 (June 2016) - List of articles

Behavioral verification of associative learning in whisker-related fear conditioning in mice

Anita Cybulska-Kłosowicz

Fear-conditioning is one of the most widely used paradigms in attempts to unravel the processes and mechanisms underlying learning and plasticity. In most Pavlovian conditioning paradigms an auditory stimulus is used as the conditioned stimulus (CS), but conditioning to a tactile CS can also be accomplished. The whisker-to-barrel tactile system in mice offers a convenient way to investigate the brain pathways and mechanisms of learning and plasticity of the cerebral cortex. To support the claim (..)

DOI: 10.21307/ane-2017-008

Published Online: 25-July-2017

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Functional correlates of brain aging: beta and gamma components of event-related band responses

Mario Christov/ Juliana Dushanova

The brain as a system with gradually declining resources by age maximizes its performance by neural network reorganization for greater efficiency of neuronal processes which is reflected in changes of event-related band responses (ERBRs) for sensory stimuli. Whether changes of high-frequency components of event-related responses are related to plasticity in neural recruitment during stabilization of sensory/cognitive mechanisms accompanying aging or are underlying pathological changes remains un(..)

DOI: 10.21307/ane-2017-009

Published Online: 25-July-2017

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Inhibition of neuronal and inducible nitric oxide synthase does not affect the analgesic effects of NMDA antagonists in visceral inflammatory pain

Dragana Srebro/ Sonja Vučković/ Milica Prostran

Previously we described the antinociceptive effect of magnesium sulfate and dizocilpine (MK-801) in the visceral and somatic rat models of pain. In the somatic model of pain, we established the influence of selective inhibitors of neuronal and inducible nitric oxide synthase on the antihyperalgesic effects of magnesium sulfate and dizocilpine. Therefore, the objective of the present study was to determine in the rat model of visceral pain whether same mechanisms are involved in the antinocicepti(..)

DOI: 10.21307/ane-2017-010

Published Online: 25-July-2017

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Pharmacokinetics and pharmacodynamics of a novel Acetylcholinesterase Inhibitor, DMNG-3

Xin-Guo Zhang/ Fei Kou/ Guo-Di MA/ Peng Tang/ Zhong-Duo Yang

DMNG-3 (3β-Methyl-[2-(4-nitrophenoxy)ethyl]-amino]con-5-enine), is a new and the potentially most potent acetylcholinesterase inhibitor recently obtained from conessine by N-demethylation and nucleophilic substitution reaction. In the present study, a step‑down passive avoidance test was used to investigate whether DMNG-3 could modulate impairment of learning and memory induced by scopolamine, and a high performance liquid chromatography (HPLC) method for the determination of DMNG-3 in biologica(..)

DOI: 10.21307/ane-2017-011

Published Online: 25-July-2017

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Surgical injury-induced early neocortical microvascular changes and characteristics of the cells populating the peri-lesion zone

Dorota Sulejczak/ Stanisław J. Chrapusta/ Wojciech Kozłowski/ Małgorzata Frontczak-Baniewicz

Adult mammalian brain contains a number of specialized neurovascular structures termed “niches” that act as sources of neuronal cells throughout the individual’s life. Some of the niches generate neurons to satisfy the need for ‘replacement’ neurons within the same or closely located brain structures, whereas the other can provide such cells for more distant destinations in the brain. A common characteristic of known neurovascular niches is the presence of a complex 3-dimensional network of basa(..)

DOI: 10.21307/ane-2017-012

Published Online: 25-July-2017

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Effects of harmonics on aesthetic judgments of music: an ERP study involving laypersons and experts

Marta Jaśkiewicz/ Piotr Francuz/ Emilia Zabielska-Mendyk/ Dariusz Zapała/ Paweł Augustynowicz

The purpose of the study was to test whether aesthetic judgments of music are affected by expertise or harmonic violation of musical sequences. The participants were 14 musical experts and 13 laypersons; they were asked to judge the beauty and correctness of extracts from J.S. Bach’s chorales. Experts and laypersons showed different late positive potential (LPP) responses to the appraisal of correctness. LPP also proved to be sensitive to the extent to which the extracts violated harmonic expect(..)

DOI: 10.21307/ane-2017-013

Published Online: 25-July-2017

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Prolonged activity evokes potentiation and the “sag” phenomenon in slow motor units of rat soleus

Hanna Drzymała-Celichowska/ Rositsa Raikova/ Piotr Krutki

Slow motor units (MUs) have no sag in their unfused tetani. This study in anesthetized rats shows that the sag can be observed in slow soleus MUs after prolonged activity. Twitches and unfused tetanic contractions were recorded from male (n=35) and female (n=39) MUs before and after the four minutes of the fatigue test (trains of 13 pulses at 40 Hz repeated every second). After this activity twitch contractions potentiated and a shift in the steep part of the force-frequency curve towards lower (..)

DOI: 10.21307/ane-2017-014

Published Online: 25-July-2017

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Somatic and dendritic perforated-patch recordings reveal β-adrenergic receptor-induced depolarization in medial prefrontal cortex pyramidal neurons

Bartłomiej Szulczyk

The aim of this perforated-patch study was to test the effect of isoproterenol on the membrane potential in mPFC (medial prefrontal cortex) pyramidal neurons. Isoproterenol depolarized the membrane potential recorded from the soma. This effect was absent in the presence of metoprolol, suggesting the involvement of β1-adrenergic receptors. The adenylate cyclase activator forskolin also depolarized the membrane potential. Moreover, the effect of isoproterenol was abolished by the adenylate cyclase(..)

DOI: 10.21307/ane-2017-015

Published Online: 25-July-2017

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