Share / Export Citation / Email / Print / Text size:

Acta Neurobiologiae Experimentalis

Nencki Institute of Experimental Biology

Polish Neuroscience Society

Subject: Behavioral Sciences , Biomedical Sciences & Nutrition , Life Sciences , Medicine , Neurosciences


ISSN: 0065-1400
eISSN: 1689-0035



Selective neuronal death following exposure to methylenedioxypyrovalerone is accompanied by an inhibition of NMDA receptor NR2B subunit expression
Neuroprotective effects of lipopolysaccharide and naltrexone co-preconditioning in the photothrombotic model of unilateral selective hippocampal ischemia in rat
Differences in spatio-temporal distribution of the visual P3b event-related potential between young men and women
Fos immunoreactivity in the intermediolateral nucleus induced by tendon vibration of the m. triceps surae in rats pretreated with a nitric oxide blocker or precursor

VOLUME 80 , ISSUE 2 (Jul 2020) - List of articles

Temporal specificity of latent inhibition in rats with daily water restriction prior to taste conditioning

Andrés Molero-Chamizo/ Guadalupe Nathzidy Rivera-Urbina

Temporal specificity of latent inhibition of conditioned taste aversion (CTA) has been demonstrated after prolonged habituation to temporal contexts in the stages preceding conditioning, and it has been eliminated by restricting consumption during conditioning. However, it is not known if latent inhibition of CTA is still dependent on the temporal context when fluid consumption is limited in the stages prior to conditioning. We tested temporal specificity of latent inhibition in rats with (diffe(..)

DOI: 10.21307/ane-2020-010

Published Online: 07-July-2020

The inhibitory effects of bile acids on catalytic and non-catalytic functions of acetylcholinesterase as a therapeutic target in Alzheimer’s disease

Leila Sadeghi/ Reza Yekta/ Gholamreza Dehghan

Acetylcholine is a fast-acting neurotransmitter in synapses and neuromuscular junctions that is decreased in Alzheimer’s disease (AD) by hyper-activation of acetylcholinesterase (AChE), which leads to progressive loss of memory and neurobehavioral abnormalities. Therefore, AChE inhibitors have therapeutic potential in AD that could include natural compounds such as bile acids. Bile acids, as potent molecules, could improve some types of neurodegenerative diseases via antioxidant effects and othe(..)

DOI: 10.21307/ane-2020-011

Published Online: 08-July-2020

Effects of sex steroid hormones on memory

Assunta Pompili/ Carla Iorio/ Antonella Gasbarri

Many evidences have elucidated relevant mechanisms of action of estrogen, progesterone, and testosterone on cognition, including learning and memory processes, both in animal models and humans. This influence may depend on their modulator role on several neurotransmitter systems, and the extensive presence of their receptors in cerebral areas, involved in cognitive functions, including the amygdala, hippocampal formation, and cerebral cortex. The present brief review summarizes data of our resea(..)

DOI: 10.21307/ane-2020-012

Published Online: 07-July-2020

Putative shared mechanisms in autism spectrum disorders and attention deficit hyperactivity disorder, a systematic review of the role of oxidative stress

Filipa Sa-Carneiro/ Conceição Calhau/ Rui Coelho/ Margarida Figueiredo-Braga

Oxidative stress is now believed to play a crucial role for neurodevelopment disorders such as autism spectrum disorders (ASD) and attention deficit hyperactivity disorder (ADHD). To review the most recent literature regarding the role of oxidative stress for the pathophysiology of ASD and ADHD, we conducted a systematic search of the relevant literature and further discuss the clinical and research implications of this knowledge. A systematic search in PubMed database retrieved 132 articles, of(..)

DOI: 10.21307/ane-2020-013

Published Online: 07-July-2020

Dependence of the filled-space illusion on the size and location of contextual distractors

Vilius Marma/ Aleksandr Bulatov/ Natalija Bulatova

For most observers, the part of the stimulus that is filled with some visual elements (e.g., distractors) appears larger than the unfilled part of the same size. This illusion of interrupted spatial extent is also known as the ‘filled-space’ or ‘Oppel-Kundt’ illusion. Although the continuously filled-space illusion has been systematically studied for over a century, there is still no generally accepted explanation of its origin. The present study aimed to further develop our computational model (..)

DOI: 10.21307/ane-2020-014

Published Online: 07-July-2020

Intracerebroventricular streptozotocin induces behavioral impairments and increases short-term C3 gene expression in the hippocampus of Wistar rats

Gabrielle Pfutzenreuter/ Kenny Nieradka/ Márcia Regina Pincerati/ Ilton Santos da Silva

A non-transgenic rat model based on intracerebroventricular injection of streptozotocin (STZ) has been used as an animal model to investigate mechanisms associated to the late onset of sporadic Alzheimer’s disease, such as anatomical and behavioral impairments. However, molecular aspects related to gene expression, mainly in the hippocampus, require more investigation. Thus, this study evaluated the early and late cognitive functions and hippocampal gene expression after STZ administration. Male(..)

DOI: 10.21307/ane-2020-015

Published Online: 07-July-2020

Hypothermia in the course of acute traumatic spinal cord injury

Jozef Kafka/ Nadezda Lukacova/ Igor Sulla/ Marcela Maloveska/ Zuzana Vikartovska/ Dasa Cizkova

In this review we briefly discuss animal experiments involving acute traumatic spinal cord injury (SCI) and the need for larger animals in testing experimental therapies. This literature overview, including the discussion of our own results from animal models, examines the use of hypothermia as a treatment method for SCI. Finally, we report the results of hypothermia application in clinical trials. Minipigs have been proposed as a potentially preferable model to rodents (typically rats) for pred(..)

DOI: 10.21307/ane-2020-016

Published Online: 07-July-2020

Anandamide in the anterior hypothalamus diminishes defensive responses elicited in mice threatened by Epicrates cenchria constrictor serpents

Tayllon dos Anjos-Garcia/ Norberto Cysne Coimbra

The purpose of this study was to investigate whether the panicolytic-like effect of different doses of anandamide microinjected into the anterior hypothalamus (AH) follows the same pattern of a bell-shaped dose-response curve observed with the same dose treatment in dorsomedial and ventromedial hypothalamus. We investigated this assumption by administering the cannabinoid and vanilloid receptor agonist anandamide into the anterior hypothalamus of mice and exposing them to the real threatening si(..)

DOI: 10.21307/ane-2020-017

Published Online: 07-July-2020

Effects of HCN channel blockade on the intensity-response function of electroretinographic ON and OFF responses in dark adapted frogs

Elka Popova/ Petia Kupenova

Hyperpolarization-activated and cyclic nucleotide-gated (HCN) channels are well expressed in the vertebrate retina. Their role in formation of electroretinographic (ERG) responses to stimulus onset (b-wave) and stimulus offset (d-wave) are largely unknown. In this study we investigated the effects of pharmacological blockade of HCN channels (with ZD7288 or ivabradine) on the ERG b- and d-waves in dark adapted frog eyecup preparations. Initially, the dose-response relationship of ZD7288 effects o(..)

DOI: 10.21307/ane-2020-018

Published Online: 07-July-2020

No Record Found..
Page Actions