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Journal of Epileptology

Foundation of Epileptology

Subject: Medicine

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eISSN: 2300-0147

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FEATURED ARTICLES

The potential mechanisms of effect of valproic acid on lipid profiles: an updated review
Ketogenic diet in epilepsy: an updated review
The interrelationship between clinical and immunity variables in epilepsy

VOLUME 22 , ISSUE 1 (June 2014) - List of articles

Handedness, cognitive processing and intelligence in patients with epilepsy

Vladimir V. Kalinin/ Daniya M. Nazmetdinova/ Alexander V. Basamygin

Introduction. The current knowledge of significance of some neurobiological and clinical variables for the development of cognitive deterioration in patients with epilepsy remains sparse and controversial. Aim. The current study has been carried out in order to elucidate the role of handedness in terms of influence on cognitive processing and intelligence in patients with epilepsy. Material and methods. One hundred and thirty two patients (62 males, 70 females, aged 27.8 ± 8.9 years) with epilep(..)

DOI: 10.1515/joepi-2015-0010

Published Online: 31-March-2014

Genetic epilepsies. remarks on the proposed “organization of the Epilepsies”

Heinz Gregor Wieser

Introduction. Genetic findings in several epilepsy syndromes provide insights into the pathophysiology of specific subtypes of epilepsy and into mechanisms of epileptogenesis, because the genes encoding ion channels, and proteins associated to the vesical synaptic cycle, or involved in energy metabolism, influence neuronal excitability. Aim. The following aspects of genetic epilepsies will be discussed: new proposed “organization of the epilepsies”, genetic and other etiologies, electroclinical (..)

DOI: 10.1515/joepi-2015-0011

Published Online: 07-April-2017

Current knowledge about epilepsy and associated psychosocial conditions

Dorota Talarska/ Joanna Stanisławska/ Magdalena Strugała/ Patrycja Talarska

Introduction. Social knowledge about epilepsy has significant influence on shaping attitudes towards people with this disorder. Aim. The aim of the article was to find out an answer to the following question: How does the level of knowledge and perceiving people with epilepsy differ across societies of different countries? Material and methods. We evaluated 30 publications published between 2000 and 2013 on measuring the knowledge about epilepsy and psycho-social functioning of people with epile(..)

DOI: 10.1515/joepi-2015-0012

Published Online: 26-June-2014

Selected classical and novel antiepileptic drugs – mechanisms of action, neuroprotection, and effectiveness in epileptic and non-epileptic conditions

Magdalena Chrościńska-Krawczyk/ Magdalena Wałek/ Bożydar Tylus/ Stanisław J. Czuczwar

Introduction. One of the most common neurological disorders is epilepsy, characterised by recurrent spontaneus seizures. Although not fully efficient in ca 30% of patients, pharmacologic treatment of epilepsy plays an important therapeutic approach not only against epilepsy. Aim. To provide data on the mechanism of action, activity and neuroprotective efficacy in experimental conditions, clinical efficacy against epilepsy and non-epileptic diseases of major, classical and newer antiepileptic dru(..)

DOI: 10.1515/joepi-2015-0013

Published Online: 26-March-2014

Successful treatment with adjunctive lacosamide in a patient with long term “drug resistant” focal epilepsy

Walter Fröscher/ Alois Rauber

Introduction. A significant number of patients suffering from epilepsy prove to be resistant to antiepileptic drugs (AEDs). Recent studies, however, suggest that 10–20% of seemingly drug resistant patients may still become seizure-free under the influence of subsequent dosage modifications. Case report. We report on a young man with cryptogenic focal epilepsy. He had his first seizure at the age of fifteen. His seizure frequency was decreased during the following 11 years. However, seizure-freed(..)

DOI: 10.1515/joepi-2015-0014

Published Online: 11-March-2014

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