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Journal of Epileptology

Foundation of Epileptology

Subject: Medicine

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eISSN: 2300-0147

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FEATURED ARTICLES

The potential mechanisms of effect of valproic acid on lipid profiles: an updated review
Ketogenic diet in epilepsy: an updated review
The interrelationship between clinical and immunity variables in epilepsy

VOLUME 23 , ISSUE 2 (December 2015) - List of articles

Radovici or Jeavons syndrome? Reply to comments

Athanasios Covanis

DOI: 10.1515/joepi-2015-0030

Is epileptogenesis a key to treatment of childhood epileptic encephalopathies?

Sergiusz Jóźwiak/ Katarzyna Kotulska

DOI: 10.1515/joepi-2015-0027

Published Online: 15-October-2015

The effect of seizures on functional status of people with spastic forms of cerebral palsy

Agata Michalska/ Janusz Wendorff

Background. Cerebral palsy (CP) is the most common childhood motor impairment. Epilepsy affects approximately one third of patients with CP. It is characterized by earlier disclosure, it is more severe and shows greater resistance than that of the general epilepsy treatment, associated with necessity for polytherapy. Its presence can result in gradual loss of function, loss of posture in non-ambulant individuals with severe disabilities and cognitive impairment risk, behavioural disorders and re(..)

DOI: 10.1515/joepi-2015-0031

Published Online: 02-June-2015

Diagnosis of epilepsy – consequences for work and professional activities

Tobias Knieß/ Hermann Stefan/ Peter Brodisch

Introduction. The correct diagnosis of epileptic seizures and non-epileptic attacks has a decisive influence on treatment, counseling and duration of possible work limitations. Diagnostic efforts should aim towards classifying the seizure as precisely as possible. For risk assessments, e.g. at the workplace, a close cooperation and networking of all professionals involved in the epilepsy treatment, care and consultation processes is required. Aim. To present guidelines for assessment of occupati(..)

DOI: 10.1515/joepi-2015-0032

Published Online: 20-October-2015

Jeavons syndrome – updated review

Athanasios Covanis

Introduction. Eyelid myoclonia and absences (ELMA) was first described by Jeavons in 1977 as a separate type of photosensitive epilepsy. Aim and method. The aim is to consider the updated electro-clinical pathophysiology and to discuss terminology, classification and differential diagnosis. The review includes our own research and relevant papers on the subject of Jeavons syndrome (JS). Review and differential diagnosis. Definition: Jeavons syndrome is a generalized idiopathic (genetic) epilepsy(..)

DOI: 10.1515/joepi-2015-0033

Published Online: 19-October-2015

The role of cannabinoids and endocannabinoid system in the treatment of epilepsy

Monika Pędracka/ Jacek Gawłowicz

Introduction. The treatment of epilepsy is still a major challenge. Despite the introduction of many new antiepileptic drugs, approximately 30% of patients still remain drug resistant. In the absence of a satisfactory therapy outcome, which is sometimes associated with numerous side effects, there is a need for new and effective drugs with low toxicity. Cannabinoids have been shown in preliminary animal model studies and in studies of patients with epilepsy to have antiepileptic activity. Aim. T(..)

DOI: 10.1515/joepi-2015-0034

Published Online: 30-November-2015

Antiepileptic drugs as a new therapeutic concept for the prevention of cognitive impairment and Alzheimer’s disease. Recent advances

Krzysztof Sendrowski/ Wojciech Sobaniec

Introduction. Excessive accumulation of amyloid-beta (A_) peptides in the brain results initially in mild cognitive impairment (MCI) and finally in Alzheimer’s disease (AD). Evidences from experimental and clinical studies show that pathological hyperexcitability of hippocampal neurons is a very early functional impairment observed in progressive memory dysfunctions. Therefore, antiepileptic drugs (AEDs) whose mechanism of action is aimed at inhibition of such neuronal hyperexcitability, seems t(..)

DOI: 10.1515/joepi-2015-0035

Published Online: 10-December-2015

Epidemiology and long-term Turku outcome of childhood-onset epilepsy and mortality. Personal experiences. Part I

Matti Sillanpää

Introduction. Epidemiological studies on epilepsy were long based, with few exceptions, on hospital and institution patients with a subsequent bias toward more difficult cases and the reported prevalence and incidence rates were often obviously too low. Few data are available on the temporal changes in the incidence of epilepsy. Aim. To study the prevalence and incidence in an unselected child population including all the children living either in the society or in the institution, temporal chan(..)

DOI: 10.1515/joepi-2015-0036

Published Online: 23-December-2015

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