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Journal of Epileptology

Foundation of Epileptology

Subject: Medicine


eISSN: 2300-0147



The potential mechanisms of effect of valproic acid on lipid profiles: an updated review
Ketogenic diet in epilepsy: an updated review
The interrelationship between clinical and immunity variables in epilepsy

VOLUME 26 , ISSUE 1-2 (June 2018) - List of articles

Long-term offspring epilepsy outcomes following planned assisted homebirth versus hospital birth

Matti Sillanpää/ Maiju M. Saarinen/ Päivi Polo-Kantola

Background. Background. Planned homebirth is an option available to a small minority of expecting mothers. Compared with hospital births, long-term risks of homebirths are poorly known. Aim. Aim. To study very long-term outcome for death, seizure remission, and other neurological long-term comorbidities Material and Methods. Material and Methods. A cohort of virtually all children (n = 230) in a geographically defined area with onset of epilepsy in or active epilepsy diagnosed prior to 1961–1964(..)

DOI: 10.21307/jepil-2018-001

Determinants of medication withdrawal strategy in the epilepsy monitoring unit*

Alendia Hartshorn/ Yasser Shahrour/ Angeline S. Andrew/ Krzysztof Bujarski

Background. Background. Video-EEG (VEEG) monitoring is a vital diagnostic tool, but there are no guidelines for withdrawal of antiepileptic drugs (AEDs). Aim. Aim. The main objectives of this study were to understand the different withdrawal strategies used in the EMU, how strategies are chosen, and the efficacy and safety of different withdrawal strategies in producing seizures. Materials and methods. Materials and methods. We retrospectively analyzed 95 consecutive patients and measured time t(..)

DOI: 10.21307/jepil-2018-006

Ketogenic diet in epilepsy: an updated review

Magdalena Dudzińska

Introduction. Introduction. Finding an effective epilepsy treatment has been a challenge in medicine for centuries. It is especially difficult to treat drug-resistant epilepsy, which accounts for 20–30% of epilepsy cases, even after the introduction of numerous new anti-epileptic drugs (AEDs). This gives an incentive to search for therapies other than pharmacotherapy, e.g. the ketogenic diet (KD). Aim. Aim. The present review paper aims to present the current state of knowledge regarding the eff(..)

DOI: 10.21307/jepil-2018-004

The potential mechanisms of effect of valproic acid on lipid profiles: an updated review

Santoso Jaeri/ Wardah Rahmatul Islamiyah

Introduction. Introduction. Valproic acid is commonly used for the treatment of epilepsy, psychiatric disorders such as bipolar disorders, anxiety and prophylaxis migraine. Long-term use of valproic acid is related with metabolic disorders such as the increase of body weight and changes of lipid profiles which are contributed to cardiovascular events, however, these associations remain unclear, furthermore, the mechanisms of these effects have not been fully elucidated. Aim. Aim. To summarize an(..)

DOI: 10.21307/jepil-2018-005

The short-term efficacy of combined hormone therapy in West syndrome

Iosif V. Volkov/ Oksana K. Volkova/ Olga S. Tashkinova/ Elena D. Belousova

Background. Background. Effective treatment protocols development for West syndrome (WS) is scientifically and economically significant. Aim. Aim. To evaluate the comparative short term efficacy and tolerability of tetracosactide at a dose of 0.03– 0.05 mg/kg and dexamethasone at a dose of 0.3–0.5 mg/kg both combined with valproate at a dose of 30–40 mg/kg/day for WS therapy. The regimen was: 1 injection daily for 10 days, following with 5 injections every other day, then 5 injections every two (..)

DOI: 10.21307/jepil-2018-002

Validation of the Polish version of the Neurological Disorders Depression Inventory for Epilepsy (P-NDDI-E)

Bartłomiej Gmaj/ Jerzy Majkowski/ Jan Szczypiński/ Joanna Jędrzejczak/ Beata Majkowska-Zwolińska/ Marcin Wojnar/ Jacek Gawłowicz/ Piotr Januszko/ Sung Pa Park/ Ewa Nagańska/ Simon Ziemka/ Dorota Wołyńczyk-Gmaj

Introduction. Introduction. Depressive symptoms are very frequent in the population of patients with epilepsy. Comorbidity between depression and epilepsy is estimated in the range of 9–62%. There are no epidemiological studies in Poland thus far in that area and there is no translated and validated screening tool for depression dedicated for persons with epilepsy (PWEs). In this study we intended to validate the Polish version of the Neurological Disorders Depression Inventory for Epilepsy (NDD(..)

DOI: 10.21307/jepil-2018-007

Heinz Gregor Wieser (1943–2018)

Jerzy Majkowski

DOI: 10.21307/jepil-2018-003

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