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North American Journal of Medicine and Science

American Chinese Medical Exchange Society

Acmes Publications Inc

Subject: Medicine

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ISSN: 1946-9357
eISSN: 2156-2342

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FEATURED ARTICLES

Screening Genetic Alterations of Biomarkers BRAF, ROS-1, and HER2 by Immunohistochemistry in Ovarian Carcinomas for Targeted Therapy
Concomitant 1q42.13-q44 Duplication and 14q32.33 Deletion: A Case Report and Review of Literature

VOLUME 10 , ISSUE 4 (December 2017) - List of articles

Introduction of a New Video-Based Eye Tracking Paradigm for Early Detection of ASD

Xuejun Kong/ Bryan K. Wang/ Joel Park/ Jian Kong

Recently, there is growing interest inapplying eye tracking technology to study infants and young children with Autism Spectrum Disorder (ASD). As a non-invasive and convenient measurement, it uses relatively objective parameters, which will greatly avoid the possibility of bias in traditional subjective evaluations caused by asymmetric information between patients (or parents) and examiners. As a result, it has been considered as having the greatest direct clinical potential for early screenin(..)

DOI: 10.7156/najms.2017.1004133

Published Online: 18-December-2017

Study on the Chemical Components of the Ethyl Acetate Extract from Herpetospermum Caudigerum

Yu-Xuan Dai/ Wei-Jie Wu/ Rui Tan

Herpetospermum seed, a common folk medicine used by Tibetan medication, is the dried ripe seed of Herpetospermum Caudigerum Wall. It is bitter in taste and cold in nature. In Tibet it is popularly known and used in traditional medicine for the treatment of liver diseases, cholic diseases, and dyspepsia. Six compounds, named Herpetin(1), Eicosanoic acid, 2-propenyl ester(2), Cucurbitacin R(3), Cucurbitacin L(4), 3'-Hydroxydaidzein(5), Oleanic acid(6), have been isolated from the ethyl acetat(..)

DOI: 10.7156/najms.2017.1004136

Published Online: 18-December-2017

The Relationship between Internet Addiction and Internalizing Problems in Overweight/Obese Adolescents: A Moderated Mediation Model

Zhen Wei/ Zhongyan Zheng/ Ying Zhang/ Rui Song/ Junli Zhu/ Guobin Wan/ Ziwen Peng

To explore the relationship of Internet addiction, coping styles, stressful life events and internalizing problems in overweight/obese adolescents, this research surveyed 1438 middle school students among which 245 overweight and obesity (non-clinical cases) were screened based on the body mass index (BMI) percentile criteria of Working Group on Obesity in China (WGOC) by a series of questionnaires and anthropometric indices. The results indicated as follows: (1) Negative coping styles played a(..)

DOI: 10.7156/najms.2017.1004139

Published Online: 18-December-2017

ASD Pathogenesis and Emerging Treatments: Lessons Learned from the Monogenic Syndromic ASD

Cun-Jian Dong/ Xuejun Kong

Autism Spectrum Disorder (ASD) is a group of complex neurodevelopmental disorders characterized by social impairments and repetitive behaviors. It can be divided into two major subcategories: 1) non-syndromic (sporadic or idiopathic) ASD and 2) syndromic ASD that also manifests other characteristic medical conditions and physical features. ASD is a growing public health crisis as its prevalence increases rapidly in recent years. There is no FDA approved drug for the treatment of ASD core sympto(..)

DOI: 10.7156/najms.2017.1004148

Published Online: 18-December-2017

Current Treatments of Prader-Willi Syndrome: A Systematic Review

Junli Zhu/ Xuejun Kong

Prader-Willi Syndrome (PWS) is a genetic imprinting disorder mainly caused by the absence of paternally expressed imprinted genes at 15q11.2-q13, maternal uniparental disomy (UPD) and imprinting defect. Typical features include hypotonia in early infancy, subsequent hyperphagia and morbid obesity, developmental delay and intellectual disability. The aims of this systematic review are to summarize the current knowledge of the treatments for PWS based on the clinical studies published from 2000 t(..)

DOI: 10.7156/najms.2017.1004156

Published Online: 18-December-2017

ASD and Sleep Disorders

Yanwei Chen/ Chunni Guo/ Bryan K. Wang/ Junli Zhu/ Xuejun Kong

Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by social communication deficits and repetitive behaviors/limited interests. There have been accumulated reports of significant sleep problems in ASD. The most common sleep problems include difficulties in sleep initiation and maintenance, irregular sleep- awakening rhythm, and disordered sleep pattern. Some investigators have suggested that sleep problems in children with ASD may be due to abnormal circadian rhythm. (..)

DOI: 10.7156/najms.2017.1004164

Published Online: 18-December-2017

Efficacy of Mindfulness- and Acceptance-Based Treatments for Culturally and Linguistically Diverse Patients: Communicating This to Patients

Edward Kimble/ Chieh Li

There is a growing consensus that the use of mindfulness- and acceptance-based behavioral therapies can result in physiological and psychological benefits in Clinical and non-Clinical populations. However, the research on the use of such therapeutic approaches with culturally and linguistically diverse (CLD) populations is still in its infancy. This article reviews the efficacy of mindfulness- and acceptance-based treatments in terms of physiological outcomes, as well as the evidence thus far f(..)

DOI: 10.7156/najms.2017.1004171

Published Online: 18-December-2017

Genotyping Technologies and Applications in the Era of Precision Medicine

Jie Huang/ Yuan Lin

Over the past decade, genotyping technologies have revolutionized the genomic research field by providing cost-effective genotyping of tens of thousands to millions of genetic markers at population scale. That became the driving force behind genome-wide association studies. The price of a genotyping chip with ~1 million variants is now less than $50. We now see large biobank studies with genotyping data, including the UK Biobank, the China Kadoorie biobank, and the US Million Veteran Program. S(..)

DOI: 10.7156/najms.2017.1004176

Published Online: 18-December-2017

Can Transarterial Chemoembolization of Hepatocellular Carcinoma Result in Transformation to Combined Hepatocellular-Cholangiocarcinoma with Stem Cell Features? A Case Study

Upasana Joneja/ Hie-Won Hann/ Daniel B. Brown/ Susan J. Littman/ Jeffrey P. Baliff

Transarterial chemoembolization (TACE) is currently one of the favored treatment modalities for non-curative hepatocellular carcinoma (HCC) and can be used to shrink tumor size in order to make a patient eligible for transplantation. Furthermore, with the advent of effective antiviral drugs for hepatitis B virus (HBV), concomitant antiviral therapy with local tumor ablation including TACE for HBV-associated HCC has been successful for long term survival. Over the last decade, however, concern h(..)

DOI: 10.7156/najms.2017.1004181

Published Online: 18-December-2017

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