VOLUME 28 (2020) - List of articles

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Clinical characteristics of forced normalization and alternative psychosis with special consideration of the new anticonvulsants

Walter Fröscher/ Volker Faust/ Tilman Steinert

Background. Background. In the case of an alternative psychosis (AP) or forced normalization (FN), the patient alternates between periods of clinically manifest seizures and normal behavior, and other periods of seizure freedom or significant seizure reduction accompanied by psychosis or behavioral disturbances. In clinical practice and in the literature, the terms AP and FN are mostly used synonymously despite small differences. FN of the EEG is not only common to interictal mental disturbances(..)

DOI: 10.21307/jepil-2020-001

Published Online: 11-February-2020

Pharmacological and non-pharmacological approaches to life threatening conditions in epilepsy

Barbara Błaszczyk/ Aleksandra Walczak/ Natalia Ścirka/ Agnieszka Konarzewska/ Barbara Miziak/ Stanisław J. Czuczwar

Background. Background. A higher degree of mortality may be attributed to patients with epilepsy. There are several main reasons responsible – sudden unexpected death in epilepsy (SUDEP), status epilepticus (SE) and central nervous system damage. Also, epilepsy associated accidents and suicidal attempts have to be highlighted. Aim. Aim. Epidemiology and therapeutic or preventive (pharmacological or non-pharmacological strategies) of the conditions increasing mortality have been reviewed so as to(..)

DOI: 10.21307/jepil-2020-002

Published Online: 23-March-2020

A BRIEF UPDATE ON PSYCHOGENIC NON-EPILEPTIC SEIZURES: A CHALLENGE TO OVERCOME

Massimiliano Beghi/ Cesare Maria Cornaggia/ Ettore Beghi

SUMMARY Psychogenic Non-Epileptic Seizures (PNES) are defined by their semiological resemblance to Epileptic Seizures (ES), not associated with specific epileptic discharges in an ictal EEG. PNES are, in fact, a feature of an underlying psychiatric disorder even if these patients are currently in the realm of epileptologists and for these reasons there is a large degree of confusion underlying the diagnosis (with an average delay of 3 years) and management of PNES. Documented PNES diagnosis woul(..)

DOI: 10.21307/jepil-2020-003

Published Online: 31-March-2020

Treatment with lacosamide or levetiracetam in patients with renal replacement therapy. What is really known?

Maya Cuhls/ Julian Bösel/ Johannes Rösche

Background. Background. Lacosamide and levetiracetam are commonly used in critically ill patients, who need an antiepileptic treatment in addition to several other medications. Since both drugs are eliminated via the kidneys, dosage has to be adapted to renal function especially in renal replacement therapy (RRT). In 2016 recommendations of dosage in this condition were based on three case reports only. Aim. Aim. To elucidate the current data basis for recommendations on the dosage of Lacosamide(..)

DOI: 10.21307/jepil-2020-004

Published Online: 04-April-2020

A position paper on breastfeeding by women with epilepsy – working group report

Joanna Jędrzejczak/ Maria Wilińska/ Ewa Kamińska/ Ryszard Lauterbach/ Ewa Helwich/ Teresa Jackowska/ Ewa Nagańska/ Natalia Jacyna/ Beata Majkowska-Zwolińska

SUMMARY Introduction. On the initiative of the General Board of the Polish Society of Epileptology a Working Group was established to develop an expert position on breastfeeding by women with epilepsy in Poland. Aim. To facilitate a unified and rational approach to breastfeeding for women with epilepsy. Methods. An ad hoc system was developed to classify available published evidence and expert opinions, which was used to evaluate recommendations on various aspects related to counselling, risk an(..)

DOI: 10.21307/jepil-2020-005

Published Online: 22-July-2020

Pharmacoresistant epilepsy associated with mutations in the KCNB1 and RELN genes. A case report

Adamantios Katerelos/ Nikolaos Zagkos/ Dimitra Alexopoulou/ Stella Mouskou/ Anastasia Korona/ Emmanouil Manolakos

SUMMARY Introduction. Epilepsy is one of the most common neurological disorders worldwide. In most cases, epilepsy can be well managed. However, there is a number of patients who do not respond well enough to common medical treatments; a situation known as pharmacoresistant epilepsy. It can be caused by mechanisms that may involve environmental and genetic factors, as well as disease or drug related factors. Case presentation. Herein we present a case report of a six-year-old girl who has been d(..)

DOI: 10.21307/jepil-2020-006

Published Online: 25-November-2020

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