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Journal of Epileptology

Foundation of Epileptology

Subject: Medicine

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eISSN: 2300-0147

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FEATURED ARTICLES

The potential mechanisms of effect of valproic acid on lipid profiles: an updated review
Ketogenic diet in epilepsy: an updated review
The interrelationship between clinical and immunity variables in epilepsy

VOLUME 28 (2020) - List of articles

Clinical characteristics of forced normalization and alternative psychosis with special consideration of the new anticonvulsants

Walter Fröscher/ Volker Faust/ Tilman Steinert

Background. Background. In the case of an alternative psychosis (AP) or forced normalization (FN), the patient alternates between periods of clinically manifest seizures and normal behavior, and other periods of seizure freedom or significant seizure reduction accompanied by psychosis or behavioral disturbances. In clinical practice and in the literature, the terms AP and FN are mostly used synonymously despite small differences. FN of the EEG is not only common to interictal mental disturbances(..)

DOI: 10.21307/jepil-2020-001

Published Online: 11-February-2020

Pharmacological and non-pharmacological approaches to life threatening conditions in epilepsy

Barbara Błaszczyk/ Aleksandra Walczak/ Natalia Ścirka/ Agnieszka Konarzewska/ Barbara Miziak/ Stanisław J. Czuczwar

Background. Background. A higher degree of mortality may be attributed to patients with epilepsy. There are several main reasons responsible – sudden unexpected death in epilepsy (SUDEP), status epilepticus (SE) and central nervous system damage. Also, epilepsy associated accidents and suicidal attempts have to be highlighted. Aim. Aim. Epidemiology and therapeutic or preventive (pharmacological or non-pharmacological strategies) of the conditions increasing mortality have been reviewed so as to(..)

DOI: 10.21307/jepil-2020-002

Published Online: 23-March-2020

A BRIEF UPDATE ON PSYCHOGENIC NON-EPILEPTIC SEIZURES: A CHALLENGE TO OVERCOME

Massimiliano Beghi/ Cesare Maria Cornaggia/ Ettore Beghi

SUMMARY Psychogenic Non-Epileptic Seizures (PNES) are defined by their semiological resemblance to Epileptic Seizures (ES), not associated with specific epileptic discharges in an ictal EEG. PNES are, in fact, a feature of an underlying psychiatric disorder even if these patients are currently in the realm of epileptologists and for these reasons there is a large degree of confusion underlying the diagnosis (with an average delay of 3 years) and management of PNES. Documented PNES diagnosis woul(..)

DOI: 10.21307/jepil-2020-003

Published Online: 31-March-2020

Treatment with lacosamide or levetiracetam in patients with renal replacement therapy. What is really known?

Maya Cuhls/ Julian Bösel/ Johannes Rösche

Background. Background. Lacosamide and levetiracetam are commonly used in critically ill patients, who need an antiepileptic treatment in addition to several other medications. Since both drugs are eliminated via the kidneys, dosage has to be adapted to renal function especially in renal replacement therapy (RRT). In 2016 recommendations of dosage in this condition were based on three case reports only. Aim. Aim. To elucidate the current data basis for recommendations on the dosage of Lacosamide(..)

DOI: 10.21307/jepil-2020-004

Published Online: 04-April-2020

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