Local orthodontic force initiates widespread remodelling of the maxillary alveolar bone

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Australasian Orthodontic Journal

Australian Society of Orthodontists

Subject: Dentistry, Orthodontics & Medicine

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ISSN: 2207-7472
eISSN: 2207-7480

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VOLUME 36 , ISSUE 2 (November 2020) > List of articles

Local orthodontic force initiates widespread remodelling of the maxillary alveolar bone

Xinyi Gong / Xiangru Huang / Yiling Yang / Siru Zhou / Qinggang Dai * / Lingyong Jiang *

Citation Information : Australasian Orthodontic Journal. Volume 36, Issue 2, Pages 175-183, DOI: https://doi.org/10.21307/aoj-2020-020

License : (CC BY 4.0)

Published Online: 20-July-2021

ARTICLE

ABSTRACT

Objectives: To clarify the effects of a local orthodontic force on alveolar bone by analysing bone remodelling in different regions of the maxilla during orthodontic tooth movement (OTM).

Methods: An OTM model was established in rats. Histological changes in the maxilla were analysed using TRAP staining, IHC staining for CTSK and haematoxylin and eosin (H and E) staining. The root bifurcation region of the alveolar bone of the first (M1), second (M2) and third (M3) molars were selected as the regions of interest (ROIs), which were further divided into a cervical and an apical level. Sequential fluorochrome labelling was performed to analyse bone deposition rates.

Results: The maxillary left first molars were moved mesially. TRAP staining and IHC staining for CTSK showed orthodontic force increased osteoclast numbers in all six ROIs at both the cervical and apical levels. H and E staining indicated elevated osteoblast numbers in the OTM group in all induced regions. Sequential fluorochrome labelling exhibited increased bone deposition rates around M1, M2 and M3 in the OTM group.

Conclusions: An orthodontic force applied to the first molar could initiate widespread remodelling of the maxillary alveolar bone, which was not restricted to the tension and pressure sites. This may revise the orthodontic biomechanical theory and provide new insights for clinical work.

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