Cephalometric assessment of soft tissue morphology of patients with acromegaly

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Australasian Orthodontic Journal

Australian Society of Orthodontists

Subject: Dentistry, Orthodontics & Medicine

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ISSN: 2207-7472
eISSN: 2207-7480

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VOLUME 32 , ISSUE 1 (May 2016) > List of articles

Cephalometric assessment of soft tissue morphology of patients with acromegaly

Nehir Canigur Bavbek * / Burcu Balos Tuncer * / Cumhur Tuncer * / Kahraman Gungor * / Cigdem Ozkan * / Emre Arslan * / Alev Eroglu Altinova * / Mujde Akturk * / Fusun Balos Toruner *

Citation Information : Australasian Orthodontic Journal. Volume 32, Issue 1, Pages 48-54, DOI: https://doi.org/10.21307/aoj-2020-112

License : (CC BY 4.0)

Published Online: 30-July-2021

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ABSTRACT

Aim: To assess the sagittal soft tissue morphology of patients with acromegaly in comparison with a healthy control group.

Methods: Twenty-seven patients with acromegaly (11 male, 16 female; mean age 47.3 ± 11.5 years) and 30 healthy subjects (15 male, 15 female; mean age 42.2 ± 17.4 years) were included in the study. Linear and angular measurements were made on lateral cephalograms to evaluate soft tissue and skeletal characteristics. The intergroup comparisons were analysed with the Student’s t-test.

Results: Facial convexity (p < 0.01) and the nasolabial angle (p < 0.001) were reduced in patients with acromegaly, whereas nose prominence (p < 0.01), upper lip sulcus depth (p < 0.01), upper lip thickness (p < 0.01), basic upper lip thickness (p < 0.01), lower lip protrusion (p < 0.05), mentolabial sulcus depth (p < 0.05) and soft tissue chin thickness (p < 0.001) were increased. Anterior cranial base length (p < 0.05), the supraorbital ridge (p < 0.01), the length of the maxilla and mandible (p < 0.001, p < 0.01, respectively) were significantly increased, and mandibular prognathism was an acromegalic feature (p < 0.05).

Conclusion: Acromegalic coarsening and thickening of the craniofacial soft tissues was identified from lateral cephalograms, which may therefore contribute to early diagnosis when evaluated together with other changes caused by the disease.

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