American National Red Cross
Subject: Medical Laboratory Technology
ISSN: 0894-203X
eISSN: 1930-3955
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Mindy Goldman * / Núria Nogués / Lilian M. Castilho
Keywords : blood group, DNA-based typing methodology, genotyping
Citation Information : Immunohematology. Volume 31, Issue 2, Pages 62-68, DOI: https://doi.org/10.21307/immunohematology-2019-072
License : (Transfer of Copyright)
Published Online: 26-October-2019
Automated testing platforms facilitate the introduction of red cell genotyping of patients and blood donors. Fluidic microarray systems, such as Luminex XMAP (Austin, TX), are used in many clinical applications, including HLA and HPA typing. The Progenika ID CORE XT (Progenika Biopharma-Grifols, Bizkaia, Spain) uses this platform to analyze 29 polymorphisms determining 37 antigens in 10 blood group systems. Once DNA has been extracted, processing time is approximately 4 hours. The system is highly automated and includes integrated analysis software that produces a file and a report with genotype and predicted phenotype results.