Severe hemolytic anemia due to auto anti-N

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Immunohematology

American National Red Cross

Subject: Medical Laboratory Technology

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ISSN: 0894-203X
eISSN: 1930-3955

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VOLUME 21 , ISSUE 2 (June 2005) > List of articles

Severe hemolytic anemia due to auto anti-N

Caroline C. Immel / Myra McPherson / Shauna N. Hay / Linda R. Braddy / Mark E. Brecher

Keywords : hemolysis, autoantibody, anemia, antigens, MNS blood group system, autoimmune hemolytic anemia

Citation Information : Immunohematology. Volume 21, Issue 2, Pages 63-65, DOI: https://doi.org/10.21307/immunohematology-2019-395

License : (Transfer of Copyright)

Published Online: 21-April-2020

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ABSTRACT

Auto anti-N is infrequently encountered and, in most reported cases,does not cause clinical hemolysis. This case reports an auto anti-N associated with severe hemolytic anemia (Hb = 2.7 g/dL) in a 6-year-old Caucasian girl with a history of vomiting, fever, and abdominal pain. Upon admission, she was found to have a metabolic acidosis,secondary to her severe anemia,with abnormal liver function tests. As in three other case reports,the autoimmune hemolytic anemia resolved,with disappearance of the auto anti-N, after corticosteroid therapy.

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