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Citation Information : Immunohematology. Volume 14, Issue 1, Pages 19-21, DOI: https://doi.org/10.21307/immunohematology-2019-648
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Published Online: 03-November-2020
The human platelet antigen system HPA-1 is involved in most cases of neonatal alloimmune thrombocytopenia and posttransfusion purpura, and occasionally causes refractoriness to platelet transfusions. Complete concordance was obtained in genotyping for HPA-1 in all samples tested with the HPA-1 genotyping kit and a ligation-based typing method. However, the genotyping kit is less sensitive than ligation-based typing, which could be of importance when testing cells from amnionic fluid or from chorionic villi.