Practical method for determination of the U status of S–s– erythrocytes

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Immunohematology

American National Red Cross

Subject: Medical Laboratory Technology

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ISSN: 0894-203X
eISSN: 1930-3955

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VOLUME 13 , ISSUE 4 (December 1997) > List of articles

Practical method for determination of the U status of S–s– erythrocytes

Marion E. Reid / Jill R. Storry / Joan Maurer / Sandra T. Nance

Keywords : U-negative, MNS blood group system, U status of S–s– red blood cells

Citation Information : Immunohematology. Volume 13, Issue 4, Pages 111-114, DOI: https://doi.org/10.21307/immunohematology-2019-724

License : (Transfer of Copyright)

Published Online: 09-November-2020

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ABSTRACT

Red blood cells (RBCs) lacking S and s blood group antigens are classified as S–s–U– or S–s–U+var but the classification may vary due to the characteristics of anti-U and to the technique used. Tests on RBCs known to lack glycophorin B (GPB) or to possess an altered form of GPB showed that polyethylene glycol-indirect antiglobulin testing or MicroTyping Systems (MTS)-gel techniques can be used as a simple and reliable way to detect RBCs with variant forms of GPB. This approach can be important in the selection of rare RBCs for transfusion to patients with undifferentiated anti-U.

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