Heat elution: a modification of the Landsteiner-Miller method

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Immunohematology

American National Red Cross

Subject: Medical Laboratory Technology

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ISSN: 0894-203X
eISSN: 1930-3955

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VOLUME 35 , ISSUE 2 (June 2019) > List of articles

Heat elution: a modification of the Landsteiner-Miller method

C. Dean-El / N. Quraishy *

Keywords : DAT, direct antiglobulin test, elution, heat elution, ABO, IgM antibodies, HDFN

Citation Information : Immunohematology. Volume 35, Issue 2, Pages 45-47, DOI: https://doi.org/10.21307/immunohematology-2020-011

License : (Transfer of Copyright)

Published Online: 15-February-2021

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ABSTRACT

Elution removes antibodies coating red blood cells and allows for serologic testing of the recovered antibodies. Heat elution may be used in the investigation of ABO hemolytic disease of the fetus and newborn, in the detection of weak A and B antigens in combination with adsorption-elution using polyclonal antibodies, and for the resolution of interfering IgM agglutinating antibodies.

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