Severe hemolytic disease of the fetus and newborn due to anti-E and anti-Jka

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Immunohematology

American National Red Cross

Subject: Medical Laboratory Technology

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ISSN: 0894-203X
eISSN: 1930-3955

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VOLUME 36 , ISSUE 2 (June 2020) > List of articles

Severe hemolytic disease of the fetus and newborn due to anti-E and anti-Jka

S. Mandal / S. Malhotra * / G. Negi / A. Tiwari / S. Mitra / S. Basu / P. Singh

Keywords : anti-E, anti-Jka, hemolytic disease of the fetus and newborn, HDFN

Citation Information : Immunohematology. Volume 36, Issue 2, Pages 60-63, DOI: https://doi.org/10.21307/immunohematology-2020-043

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Published Online: 17-February-2021

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ABSTRACT

Red blood cell alloimmunization to antigens other than D, such as C, c, E, e, and antigens in the Kell, MNS, and Duffy blood group systems, has emerged as an important cause of hemolytic disease of the fetus and newborn (HDFN). Antibody screening for these antibodies is not routinely practiced for all antenatal patients in developing countries, mainly because of financial constraints. Here we report a rare case of HDFN due to dual antibodies to Rh and Kidd blood group system antigens: anti-E and anti-Jka. This case report highlights the importance of routine and regular antenatal screening of all pregnant women for proper monitoring and follow-up.

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