Cognitive impairment predicts social disability in persons with epilepsy


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Journal of Epileptology

Foundation of Epileptology

Subject: Medicine


eISSN: 2300-0147





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VOLUME 22 , ISSUE 2 (December 2014) > List of articles

Cognitive impairment predicts social disability in persons with epilepsy

Krzysztof A. Bujarski * / Gabriella Wozniak / Erik J. Kobylarz

Keywords : epilepsy, cognitive impairment, social disability

Citation Information : Journal of Epileptology. Volume 22, Issue 2, Pages 89-97, DOI:

License : (CC BY 4.0)

Received Date : 19-May-2014 / Accepted: 20-August-2014 / Published Online: 29-August-2014



Introduction. Cognitive dysfunction is one of the main comorbidities of epilepsy which co-exists with seizures and contributes to the adverse impact of the disease on employment, education and interpersonal relationships. A fundamental question regarding cognitive dysfunction in epilepsy goes as follows: in comparison to seizures, what role does cognitive dysfunction play in causing social disability? The purpose of this review was to evaluate our understanding of the role cognitive impairment plays in social disability in persons with epilepsy (PWE). We systematically searched the medical literature and identified studies which assessed the impact of seizures and cognitive function on some aspect of social disability in PWE.

Results and Discussion. We identified 12 studies which adequately measured all variables in non-surgical cohorts, and 9 studies of cohorts following epilepsy surgery. We found evidence from non-surgical and from surgical series that cognitive variables strongly correlate with levels of social disability.

Conclusions. We conclude that efforts to better understand the origins of cognitive dysfunction in epilepsy and subsequently at developing treatment modalities will be needed in order to reduce the degree of social disability caused by the condition.

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