The role of the hepatic metabolisation for the interaction between valproic acid and carbapenem antibiotics

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Journal of Epileptology

Foundation of Epileptology

Subject: Medicine

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eISSN: 2300-0147

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VOLUME 24 , ISSUE 2 (December 2016) > List of articles

The role of the hepatic metabolisation for the interaction between valproic acid and carbapenem antibiotics

Johannes Rösche *

Citation Information : Journal of Epileptology. Volume 24, Issue 2, Pages 85-86, DOI: https://doi.org/10.1515/joepi-2016-0008

License : (CC BY 4.0)

Received Date : 30-August-2016 / Accepted: 05-September-2016 / Published Online: 07-September-2016

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REFERENCES

González C., Villena R.: Interacción entre meropenem y ácido valproica: A propósito de dos casos pediátricos. Revista chilena de infectológia, 2012, 29: 353–356.

 

Keränen T., Kuusisto H.: Concomitant treatment with imipenem causes a rapid and extensive decrease in the plasma concentrations of valproic acid. Journal of Epileptology, 2016, 24: 63–66.

 

Mancl E.E., Gidal B.E.: The effect of carbapenem antibiotics on plasma concentrations of valproic acid. The Annals of Pharmacotherapy, 2009, 43: 2082–2087.

 

Rösche J., Pohley I., Jung S.-U., Benecke R.: Meropenem and valproic acid – a combination with a high risk of severe interaction. Aktuelle Neurologie, 2014, 41: 162–166.

 

Spriet I., Goyens J., Meersseman W., Wilmer A., Willems L., Van Paesschen W.: Interaction between valproate and meropenem: a retrospective study. The Annals of Pharmacotherapy, 2007, 41: 1130–1136.

 

Spriet I., Willems L.: No interaction between valproate and meropenem in a cirrhotic patient. The Annals of Pharmacotherapy, 2011, 45: 1167.

 

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