The role of ultrasound and nuclear medicine methods in the preoperative diagnostics of primary hyperparathyroidism


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Journal of Ultrasonography

Polish Ultrasound Society (Polskie Towarzystwo Ultrasonograficzne)

Subject: Medicine


ISSN: 2084-8404
eISSN: 2451-070X





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VOLUME 15 , ISSUE 63 (December 2015) > List of articles

The role of ultrasound and nuclear medicine methods in the preoperative diagnostics of primary hyperparathyroidism

Michał Nieciecki * / Marek Cacko / Leszek Królicki

Keywords : hyperparathyroidism, ultrasonography, scintigraphy, PET

Citation Information : Journal of Ultrasonography. Volume 15, Issue 63, Pages 398-409, DOI:

License : (CC BY-NC-ND 4.0)

Received Date : 30-September-2015 / Accepted: 26-October-2015 / Published Online: 13-September-2016



Primary hyperparathyroidism (PH) represents one of the most common endocrine diseases. In most cases, the disorder is caused by parathyroid adenomas. Bilateral neck
exploration has been a widely used treatment method for adenomas since the 20’s of the twentieth century. In the last decade, however, it has been increasingly replaced
by a minimally invasive surgical treatment. Smaller extent, shorter duration and lower complication rate of such a procedure are emphasized. Its effi cacy depends on a precise location of parathyroid tissue during the preoperative imaging. Scintigraphy and ultrasound play a major role in the diagnostic algorithms. The effi cacy of both methods has been repeatedly verifi ed and compared. The still-current guidelines of the European Association of Nuclear Medicine (2009) emphasize the complementary role of scintigraphy and ultrasonography in the preoperative diagnostics in patients with primary hyperparathyroidism. At the same time, attempts are made to improve both these techniques by implementing new study protocols or innovative technologies. Publications have emerged in the recent years in the fi eld of ultrasonography, whose authors pointed out the usefulness of elastography and contrast media. Nuclear medicine studies, on the other hand, focus mainly on the assessment of new radiotracers used in the positron emission tomography (PET). The aim of this article is to present, based on literature data, the possibilities of ultrasound and scintigraphy in the preoperative diagnostics in patients with primary hyperparathyroidism. Furthermore, the main directions in the development of imaging techniques in PH patients were evaluated.

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