Granulomatous prostatitis after intravesical immunotherapy mimicking prostate cancer

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Journal of Ultrasonography

Polish Ultrasound Society (Polskie Towarzystwo Ultrasonograficzne)

Subject: Medicine

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ISSN: 2084-8404
eISSN: 2451-070X

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VOLUME 16 , ISSUE 67 (December 2016) > List of articles

Granulomatous prostatitis after intravesical immunotherapy mimicking prostate cancer

Waldemar Białek * / Sławomir Rudzki / Paweł Iberszer / Lech Wronecki

Keywords : granulomatous prostatitis, prostate biopsy, transrectal ultrasound

Citation Information : Journal of Ultrasonography. Volume 16, Issue 67, Pages 404-410, DOI: https://doi.org/10.15557/JoU.2016.0040

License : (CC BY-SA 4.0)

Received Date : 06-July-2015 / Accepted: 25-October-2015 / Published Online: 24-February-2017

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ABSTRACT

Intravesical immunotherapy with attenuated strains of Mycobacterium bovis is a widely used therapeutic option in patients with non-muscle-invasive transitional cell carcinoma of the bladder. A rare complication of intravesical therapy with the Bacillus Calmette-Guérin vaccine is granulomatous prostatitis, which due to increasing levels of prostate-specific antigen and abnormalities found in transrectal examination of the prostate may suggest concomitant prostate cancer. A case of extensive granulomatous prostatitis in a 61-year-old patient which occurred after the first course of a well-tolerated Bacillus Calmette-Guérin therapy is presented. Due to abnormalities found in rectal examination and an abnormal transrectal ultrasound image of the prostate with extensive infiltration mimicking neoplastic hyperplasia a core biopsy of the prostate was performed. Histopathological examination revealed inflammatory infiltration sites of tuberculosis origin.

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