Antimicrobial Activity of Penicillin G and N-acetylcystein on Planktonic and Sessile Cells of Streptococcus suis

Publications

Share / Export Citation / Email / Print / Text size:

Polish Journal of Microbiology

Polish Society of Microbiologists

Subject: Microbiology

GET ALERTS

ISSN: 1733-1331
eISSN: 2544-4646

DESCRIPTION

0
Reader(s)
0
Visit(s)
0
Comment(s)
0
Share(s)

SEARCH WITHIN CONTENT

FIND ARTICLE

Volume / Issue / page

Related articles

VOLUME 65 , ISSUE 1 (March 2016) > List of articles

Antimicrobial Activity of Penicillin G and N-acetylcystein on Planktonic and Sessile Cells of Streptococcus suis

Ivette Espinosa * / Michel Báez / Evelyn Lobo / Siomara Martínez / Marcelo Gottschalk

Keywords : Streptococcus suis, biofilm, N-acetylcystein, Penicillin G

Citation Information : Polish Journal of Microbiology. Volume 65, Issue 1, Pages 105-109, DOI: https://doi.org/10.5604/17331331.1197282

License : (CC BY-NC-ND 4.0)

Received Date : 24-February-2015 / Accepted: 05-October-2015 / Published Online: 15-March-2016

ARTICLE

ABSTRACT

The aim of this study was to investigate the capacity of Streptococcus suis strains to form biofilms and to evaluate the antimicrobial activity of Penicillin G and N-acetylcystein (NAC) on both S. suis sessile and planktonic forms. Only non-typeable isolates of S. suis were correlated with a greater biofilm formation capacity. The MCI of Penicillin G and NAC required for inhibiting biofilm growth were higher than the required concentration for inhibiting planktonic growth. The combinations of NAC and Penicillin G showed a strong synergistic activity that inhibited biofilm formation and disrupted the pre-formed biofilm of S. suis.

Content not available PDF Share

FIGURES & TABLES

REFERENCES

Aslam S., B.W Trautner, V. Ramanathan and R.O. Darouiche. 2007. Combination of tigecycline and N-acetylcysteine reduces biofilm-embedded bacteria on vascular catheters. Antimicrob. Agents Chemother. 51: 1556–1558.

 

Bonifait L., L. Grignon and D. Grenier. 2008. Fibrinogen induces biofilm formation by Streptococcus suis and enhances its antibiotic resistance. Appl. Environ. Microbiol. 74(15): 4969–4972.

 

Bonifait L., M. Gottschalk and D. Grenier. 2010. Cell surface characteristics of nontypeable isolates of Streptococcus suis. FEMS Microbiol. Lett. 311(2): 160–166.

 

Clinical and Laboratory Standards Institute (CLSI). 2008. Performance standards for antimicrobial susceptibility testing. 18th Infor-mational supplement, M100-S18. Wayne, PA.

 

Gottschalk M., M. Segura and J. Xu. 2007. Streptococcus suis infections in humans: the Chinese experience and the situation in North America. Anim. Health Res. Rev. 8: 29–45.

 

Grenier D., L. Grignon and M. Gottschalk. 2009. Characterisation of biofilm formation by a Streptococcus suis meningitis isolate. Vet. J. 179: 292–295.

 

Guo D., L. Wang and L. Chengping. 2012. In vitro biofilm forming potential of Streptococcu suis isolated from human and swine in China. Braz. J. Microbiol. 43(3): 993–1004.

 

Hajdu S., A. Lassnigg, W. Graninger, A.M. Hirschl and E. Presterl. 2009. Effects of vancomycin, daptomycin, fosfomycin, tigecyclin and ceftriaxone on Staphylococcus epidermidis biofilms. J. Orthop Res. 27: 1361–1365.

 

Higgins R. and M. Gottschalk. 1990. An update on Streptococcus suis identification. J. Vet. Diagn. Invest. 2: 249–252.

 

Huaijie H., H. Wenjia, L. Peng, L. Qingyu, Z. Xiaotao, J. Hua, W. Yanzi, Z. Xin, Z. Yuling, L. Jianchun and others. 2013. Effect of licochalcone A on growth and properties of Streptococcus suis. PLoS One 8(7): e67728.

 

Huang Y.T., L.J. Teng, S.W. Ho and P.R. Hsueh. 2005. Streptococcus suis infection. J. Microbiol. Immunol. Infect. 38: 306–313.

 

Hui A.C., K.C. Ng, P.Y. Tong, V. Mok and K.M. Chow. 2005. Bacterial meningitis in Hong Kong:10-years’ experience. Clin. Neurol. Neurosurg. 107: 366–370.

 

Lun Z.R., Q.P. Wang, X.G. Chen, A. Li and X.Q. Zhu. 2007. Streptococcus suis: anemerging zoonotic pathogen. Lancet Infect. Dis. 7: 201–209.

 

Mackay M.L., K. Milne and I.M. Gould. 2000. Comparison of methods for assessing synergic antibiotic interactions. Int. J. Antimicrob. Agents. 15(2): 125–129.

 

Marchese A., M. Bozzolasco, L. Gualco, E.A. Debbia, G.C. Schito and A.M. Schito. 2003. Effect of fosfomycin alone and in combi-nation with N-acetylcysteine on E. coli biofilms. Int. J. Antimicrob Agents. 22: 95–100.

 

Marois C., M. Le Devendec and M. Gottschalk. 2007. Detection and molecular typing of Streptococcus suis in tonsils from live pigs in France. Can. J. Vet. Res. 71(1): 14–22.

 

Merle E., H.C. Olson, W.M. Douglas, A.G. Buret and R. Ronald. 2012. Read biofilm bacteria: formation and comparative susceptibility to antibiotics. Can. J. Vet. Res. 66:86–92.

 

Schwandt L.Q., W. Van, I. Stokroos, M. der Van, H.J. Busscher and F.W. Albers. 2004. Prevention of biofilm formation by dairy products and N-acetylcysteine on voice prosthees in an artificial throat. Acta Otolaryngol. 124(6): 726–731.

 

Wang K., W. Fan, H. Wisselink and C. Lu. 2011. The cps locus of Streptococcus suis serotype 16: Development of a serotype-specific PCR assay. Vet. Microbiol. 153: 403–406.

 

EXTRA FILES

COMMENTS