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  • Immunohematology

 

Case report

Weak D type 67 in four related Canadian blood donors

Philip Berardi, Emma Bessette, Michiko Ng, Nancy Angus, Debra Lane, Lise Gariepy, Katerina Pavenski, Gorka Ochoa-Garay, Jacqueline Cote, Mindy Goldman

Immunohematology, Volume 31 , ISSUE 4, 159–162

Report | 01-December-2019

Alloimmunization of patients by blood units harboring distinct DEL variants

Maryse St-Louis, André Lebrun, Mindy Goldman, Marianne Lavoie

Immunohematology, Volume 29 , ISSUE 4, 136–140

Case report | 01-December-2019

Molecular analysis of patients with weak D and serologic analysis of those with anti-D (excluding type 1 and type 2)

included autologous controls, direct antiglobulin test, elution, and titration of anti-D before and after adsorption of serum onto autologous RBCs. From molecular analyses, 459 individuals exhibited a weak D type. We described seven novel RHD variant alleles. The most frequent types of weak D were type 1 (30.1%), type 2 (23.7%), type 4.0 (10.2%), type 4.2.2 (20.3%), type 11 (3.9%), and type 15 (3.7%). Anti-D was identified in the sera of 9 of 47 individuals with weak D type 4.0, in 14 of 93 with weak D

Bach-Nga Pham, Michèle Roussel, Dominique Gien, Maryline Ripaux, Carine Auxerre, Pierre-Yves Le Pennec, Christine Andre-Botte

Immunohematology, Volume 29 , ISSUE 2, 55–62

Article | 17-February-2021

Identifying obstetrics patients in whom RHD genotyping can be used to assess risk of D alloimmunization

years.9,14,15 Particular RHD variant alleles are known to be more prevalent in different ethnic groups. The most common RHD variants in Caucasian individuals are RHD*weak D types 1, 2, and 3, where the sample is often negative in tube by direct agglutination, but positive by the indirect antiglobulin test (IAT).8 These alleles are not associated with alloimmunization.16 Individuals of African descent, however, are more likely to express a partial D phenotype, which can either present as strongly D

T.N. Horn, J. Keller, M.A. Keller, L. Klinger

Immunohematology, Volume 36 , ISSUE 4, 146–151

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