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Research Article

APPLICATION OF THE BACTERIAL OUTER MEMBRANE VESICLES IN VACCINE DESIGN

Outer membrane vesicles (OMVs) are extracellular structures produced by most gram‑negative bacteria, including pathogens of humans and animals. OMVs play an important role in the physiology of microorganisms and are an integral part of many biological processes. Following the discovery that they are able to transport many biomolecules, also these which have the ability to interact with the immune system, their potential use as non‑replicating vaccines has become an important aspect of

Joanna Jadwiga Klim, Renata Godlewska

Postępy Mikrobiologii - Advancements of Microbiology , ISSUE 1, 43–55

Research Article

SECRETION OF OUTER MEMBRANE VESICLES AS A MECHANISM PROMOTING H. PYLORI INFECTIONS

Helicobacter pylori commonly colonizes the human gastric mucosa. Infections with this microorganism can contribute to serious health consequences, such as peptic ulceration, gastric adenocarcinoma and gastric mucosa-associated lymphoid tissue lymphoma. Chronic persistence of this bacteria in the host organism is probably strongly dependent on the secretion of outer membrane vesicles (OMV). These organelles are small, electron-dense, extracellular structures which are secreted in large amounts

Paweł Krzyżek

Postępy Mikrobiologii - Advancements of Microbiology , ISSUE 3, 316–325

original-paper

Influence of Environmental and Genetic Factors on Proteomic Profiling of Outer Membrane Vesicles from Campylobacter jejuni

Introduction The outer membrane (OM) of Gram-negative bacteria can naturally bulge out, entraps periplasmic content and pinches off to form spheres of 50–250 nm in diameter called outer membrane vesicles (OMVs). OMVs contain mostly outer membrane-associated and periplasmic proteins, but also cytoplasm-located molecules, quorum-signaling molecules, DNA and RNA and, thus, provide bacteria with means to interact adaptively with their environment, host and other microorganisms (Schwechheimer and

RENATA GODLEWSKA, JOANNA KLIM, JANUSZ DĘBSKI, AGNIESZKA WYSZYŃSKA, ANNA ŁASICA

Polish Journal of Microbiology , ISSUE 2, 255–261

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