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Mini Review

Brucella – Virulence Factors, Pathogenesis and Treatment

Brucellae are Gram-negative, small rods infecting mammals and capable of causing disease called brucellosis. The infection results in abortion and sterility in domestic animals (sheeps, pigs, rams etc). Especially dangerous for humans are: Brucella melitensis, Brucella suis, Brucella abortus, and Brucella canis that trigger unspecific symptoms (flu-like manifestation). Brucella rods are introduced via host cells, by inhalation, skin abrasions, ingestion or mucosal membranes. The most important

PATRYCJA GŁOWACKA, DOROTA ŻAKOWSKA, KATARZYNA NAYLOR, MARCIN NIEMCEWICZ, AGATA BIELAWSKA-DRÓZD

Polish Journal of Microbiology , ISSUE 2, 151–161

original-paper

Clinical Interpretation of Detection of IgM Anti-Brucella Antibody in the Absence of IgG and Vice Versa; a Diagnostic Challenge for Clinicians

constitutes a broad range of signs and symptoms. Patients commonly present with fever, chills, fatigue, joint, muscle and back pain. The fact that symptoms are non-specific and can be shared by other infectious diseases makes it even more difficult for clinicians to diagnose it clinically. Although the diagnosis is confirmed by isolation of the Brucella spp. from tissues or body fluids, the occupational risk of infection transmission to laboratory staff and the time-consuming and less sensitive culture

REEM AL JINDAN, NIDA SALEEM, AAMIR SHAFI, SHEIKH MUHAMMAD AMJAD

Polish Journal of Microbiology , 1–7

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