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original-paper

Clinical Interpretation of Detection of IgM Anti-Brucella Antibody in the Absence of IgG and Vice Versa; a Diagnostic Challenge for Clinicians

course, the detection of specific IgM antibody in the absence of specific IgG antibody might be confusing for treating physician and therefore risks misdiagnosis of active brucellosis. Likewise, clinical interpretation of Brucella-specific IgG antibodies in the absence of IgM also creates confusion for clinicians. While some studies conducted on the diagnostic accuracy of ELISA mentioned a combined specificity of 100% for Brucella-specific IgM and IgG (Özdemir et al. 2011; Asaad et al. 2012), some

REEM AL JINDAN, NIDA SALEEM, AAMIR SHAFI, SHEIKH MUHAMMAD AMJAD

Polish Journal of Microbiology , ISSUE 1, 51–57

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