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Polish Journal Of Microbiology

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Clinical Interpretation of Detection of IgM Anti-Brucella Antibody in the Absence of IgG and Vice Versa; a Diagnostic Challenge for Clinicians

examination has led to consider other diagnostic techniques more useful in the diagnostic workup of brucellosis. Serologically, ELISA is the most popular and widely used diagnostic assay. Brucella-specific IgM antibodies are produced in the first week after the disease onset, reaching a maximum after two months. On the other hand, IgG antibodies are detected after the second week of infection, attaining a peak level of six to eight weeks later. While IgG response coincides more closely with the clinical

REEM AL JINDAN, NIDA SALEEM, AAMIR SHAFI, SHEIKH MUHAMMAD AMJAD

Polish Journal of Microbiology , ISSUE 1, 51–57