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Case report

Central Pontine Myelinolysis

Central Pontine Myelinolysis (CPM) commonly presents as a complication of treatment in patients with profound life threatening hyponatraemia. It occurs when the sodium level is corrected too rapidly. Hyponatraemia should never be corrected at a rate greater than 8-10mmol/L of sodium per day. Rapid correction causes extracellular tonicity and will continue to drive water out of the brain’s cells leading to cellular dysfunction. Frequent clinical signs include dysphagia

Leigh Arrowsmith, Christopher Tolar

Australasian Journal of Neuroscience , ISSUE 1, 15–19

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