The aim of this study was to explore the plasmid characteristics of eight clinical Enterobacteriaceae strains containing extended broad spectrum beta-lactamases and plasmid-mediated quinolone resistance. Plasmids were transferred by conjugation or transformation and resistance determinants were investigated by PCR. We showed that at least one plasmid harbouring qnrB or qnrS determinant was transferred by conjugation in five isolates. QepA determinant was confirmed to be on a non
Fethiye Ferda Yilmaz,
Sabire Sohret Aydemir,
Polish Journal of Microbiology , ISSUE 4, 529–532
microorganisms. Due to problems with the comparison of certain species, novel methods based on the analysis of proteins have been applied. In-depth analysis of Enterobacteriaceae family showed that its members are more dissimilar than previously thought, which eventually led to dividing this family into seven families and resulted in a change to the name of the order: from Enterobacteriales to Enterobacterales. These changes were applied in some biggest accessible databases. However, there are still many
Postępy Mikrobiologii - Advancements of Microbiology , ISSUE 4, 465–469
Fluoroquinolones (FQ) are broad-spectrum antimicrobial agents widely used to treat a range of infections in clinical medicine. However, the surveillance studies demonstrate that fluoroquinolone resistance rates increased in Enterobacteriaceae in the past years. FQ inhibit bacterial DNA synthesis by interfering with the action of two bacterial enzymes – DNA gyrase and topoisomerase IV. There are two categories of quinolone resistance mechanisms: chromosomally encoded and acquired
Postępy Mikrobiologii - Advancements of Microbiology , ISSUE 1, 47–57
, Paenibacillus and some members of the Enterobacteriaceae is gaining worldwide importance and acceptance and appears to be the trend for the future.
Walid Fediala Abd El-Gleel Mosa,
Polish Journal of Microbiology , ISSUE 3, 243–251
Klebsiella pneumoniae carbapenemase (KPC) have become a major therapeutic challenge because of its increasingly fast dissemination throughout the world. Accurate detection of KPC is essential for optimal treatment. The Clinical and Laboratory Standards Institutes (CLSI) for fast detection of KPC producers currently recommend Modified Hodge Test (MHT) and Carba NP test. MHT can directly detect carbapenemase production in Enterobacteriaceae isolates. The current study was conducted to evaluate
Polish Journal of Microbiology , ISSUE 3, 291–295
In recent years, the phenomenon of spreading antibiotic-resistant strains has been reported in Poland as well as around the world . In 2013, The Centres for Disease Control and Prevention (CDC) published a report describing the microorganisms that constitute the greatest public health threat in the United States, among which in the first place is occupied by carbapenem-resistant Enterobacteriaceae strains (CRE – Carbapenem – Resistant (CR) Enterobacteriaceae) [3, 45].
Sylwia Joanna Chmielewska,
Postępy Mikrobiologii - Advancements of Microbiology , ISSUE 3, 271–289