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Original Research

Clinicopathologic Characteristics of EGFR Mutations in Non-Small Cell Lung Cancer (NSCLC) in Central New York

other countries.4 Factors that may attribute to cancer in this sub-population may be environmental and/or genetic.5,6 Epidermal growth factor receptor (EGFR) tyrosine kinase (TK) domain mutations as well as EMAP-like protein 4 (EML4)-anaplastic lymphoma kinase (ALK) fusion are found more commonly in never smokers4,7 A review of EGFR mutation prevalence in lung adenocarcinoma demonstrated 45% of Asian/Pacific, 24% White, 20% African American, 17% Hispanic, and 52% Asian/Indian with EGFR mutations.8

Daniel J. Zaccarini, Brittany Depasquale, Aarati Poudel, Steven Graziano, Shengle Zhang

North American Journal of Medicine and Science , ISSUE 1, 1–5

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