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Article | 15-February-2021

An update on the JR blood group system

Update on the JR System The JR blood group system consists of one antigen, Jra, which is of high prevalence in all populations. Anti-Jra has caused transfusion reactions and been involved in hemolytic disease of the fetus and newborn. The Jra antigen is located on ABCG2 transporter, a multipass membrane glycoprotein, which is encoded by the ABCG2 gene on chromosome 4q22.1. Several null alleles of ABCG2 (nonsense, deletions, and insertions) are responsible for the Jr(a–) phenotype, and the

L. Castilho

Immunohematology, Volume 35 , ISSUE 2, 43–44

Review | 01-December-2019

A review of the JR blood group system

The JR blood group system (ISBT 032) consists of one antigen, Jra, which is of high prevalence in all populations. The rare Jr(a–) phenotype has been found mostly in Japanese and other Asian populations, but also in people of northern European ancestry, in Bedouin Arabs, and in one Mexican. Anti-Jra has caused transfusion reactions and is involved in hemolytic disease of the fetus and newborn. The Jra antigen is located on ABCG2 transporter, a multipass membrane glycoprotein (also known

Lilian Castilho, Marion E. Reid

Immunohematology, Volume 29 , ISSUE 2, 63–68

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