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1. What are immune peptides Peptides of immunity – HDPs (Host Defense Peptides), form a complex of old, evolutionarily preserved effector molecules synthesized by the organisms of mammals (humans, animals – including marsupials and monotremes), birds, reptiles, amphibians, fish, insects and plants. Even microorganisms have not developed a defence mechanism against these substances along their evolutionary path, hence HDPs are often referred to as natural antibiotics [36, 56, 60, 87, 89, 93, 94

Jakub Deptuła, Beata Tokarz-Deptuła, Magdalena Malinowska-Borysiak, Michał Stosik, Wiesław Deptuła

Postępy Mikrobiologii - Advancements of Microbiology , ISSUE 1, 19–28

Research Article


Rotavirus (RV) infections are a major epidemiological problem in humans and farm animals. So far, a number of human and animal RV strains have been identified. Based on the antigenic properties of the VP6 capsid protein, they have been classified into eight serogroups (A-H). The most important of them are viruses from group A (RVA), which are responsible for more than 90% of cases of rotaviral diarrhoea. The segmented structure of the virus genome and the presence of animals in human

Iwona Kozyra, Artur Rzeżutka

Postępy Mikrobiologii - Advancements of Microbiology , ISSUE 2, 156–166



1. Introduction The occurrence of resistant bacteria in animals usually arouses interest and even provokes anxiety, mainly due to the potential risk to people or to the public health [3, 45]. Bacteria living in animals do not live in isolation and remain in close relationships with other microorganisms, as well as the host itself, or microorganisms of other living organisms and ecosystems. This may result in the mutual transfer of genes and the acquisition of new features by the recipients

Marian Binek, Magdalena Kizerwetter-Świda, Magdalena Rzewuska, Dorota Chrobak-Chmiel, Agnieszka Sałamaszyńska-Guz

Postępy Mikrobiologii - Advancements of Microbiology , ISSUE 3, 259–270

Research Article


More and more attention has been paid to environmental chlamydiae in recent years. They were classified as pathogenic bacteria for both humans and animals. Thanks to molecular biology techniques, the following nine families of environmental chlamydiae were assigned to the order of Chlamydiales: Candidatus Clavichlamydiaceae, Criblamydiaceae, Parachlamydiaceae, Candidatus Piscichlamydiaceae, Rhabdochlamydiaceae, Simkaniaceae, Waddliaceae, Candidatus Actinochlamydiacae and Candidatus

Małgorzata Pawlikowska-Warych, Joanna Palma, Wiesław Deptuła

Postępy Mikrobiologii - Advancements of Microbiology , ISSUE 3, 265–274

Original Paper

A Special Risk Group for Hepatitis E Infection: The First Record of North Cyprus

Abstract Hepatitis E virus (HEV) is transmitted by a fecal oral route from animals to humans following exposure to the body fluids of infected animals. We investigated the seroprevalence of anti-hepatitis E (anti-HEV) antibodies by monitoring IgG and IgM virus antibodies amongst employees in the animal industry in North Cyprus through a cross-sectional study. Samples were taken from individuals without occupational exposure to animals and from those who worked with animals (doing animal


Polish Journal of Microbiology , ISSUE 4, 525–528

Research Article


Katarzyna Talaga-Ćwiertnia, Małgorzata Bulanda

Postępy Mikrobiologii - Advancements of Microbiology , ISSUE 3, 244–250

Research Article


Currently, the emergence of exotic diseases in areas where they have not previously occurred is reported more frequently. For this reason, the World Organization for Animal Health (OIE) and individual countries are introducing regulations aimed at preventing and combating these diseases. Globalization and intensification of the trade of animals and food products of animal origin contributes to the transmission of infectious animal diseases throughout the world. Global warming and human

Katarzyna Krasoń, Magdalena Larska

Postępy Mikrobiologii - Advancements of Microbiology , ISSUE 4, 385–397

Short Communication

Detection of Coxiella burnetii and Francisella tularensis in Tissues of Wild-living Animals and in Ticks of North-west Poland

Abstract This work presents results of the research on the occurrence of Coxiella burnetii and Francisella tularensis in the tissues of wild-living animals and ticks collected from Drawsko County, West Pomeranian Voivodeship. The real-time PCR testing for the pathogens comprised 928 samples of animal internal organs and 1551 ticks. The presence of C. burnetii was detected in 3% of wild-living animals and in 0.45–3.45% (dependent on collection areas) of ticks. The genetic sequences of F


Polish Journal of Microbiology , ISSUE 4, 529–534


C60 fullerenes increase the intensity of rotational movements in non-anesthetized hemiparkinsonic rats

nanostructures, such as pristine C60 fullerenes, may be used as potential antioxidants (Gharbi et al., 2005). It is important that low and even high doses of such fullerenes do not present any acute or subacute toxicity in the animals; the maximum tolerated dose of C60 fullerene for both oral and intraperitoneal (i.p.) administration in rats was found to be 5 g/kg (Gharbi et al., 2005). In our previous electrophysiological and biochemical study, we investigated the effect of pristine C60 fullerene aqueous

Andriy V. Maznychenko, Olena P. Mankivska, Inna V. Sokolowska (Vereshchaka), Bohdan S. Kopyak, Tomasz Tomiak, Nataliya V. Bulgakova, Olga O. Gonchar, Yuriy I. Prylutskyy, Uwe Ritter, Iryna V. Mishchenko, Alexander I. Kostyukov

Acta Neurobiologiae Experimentalis , ISSUE 1, 32–37


Extensively Drug-resistant Acinetobacter baumannii Belonging to International Clone II from A Pet Cat with Urinary Tract Infection; The First Report from Pakistan

other farm animals have been increasing (Ewers et al. 2017). The information on A. baumannii in veterinary settings is, however, limited, and data related to the comparison of strains isolated from the humans and veterinary sources are quite inadequate (van der Kolk et al. 2019). From Pakistan, this is the very first report of extensively drug-resistant (XDR) CRAB isolates harboring the acquired the bla-OXA-23 and armA genes from an infected pet cat, which drives the attention towards the possible


Polish Journal of Microbiology , ISSUE 2, 231–234

Research paper

Effects of extensive amygdaloid lesions on conditioned taste aversion in rats

acquisition of CTA, as has been reported with selective lesions of the basolateral amygdala. The magnitude of the taste aversion of animals with extensive lesions of the amygdala was compared with those of animals with similar lesions of the striatum (a structure apparently unrelated to CTA) and animals without lesions. Taste aversion was analyzed by the one-bottle test and two-bottle choice test. The results of the one-bottle test indicated that amygdaloid lesions significantly reduced the magnitude of

Andrés Molero-Chamizo

Acta Neurobiologiae Experimentalis , ISSUE 3, 242–250



The Swarm Intelligence is a new and modern method employed in optimization problems. The Swarm Intelligence method is based on the en masse movement of living animals like birds, fishes, ants and other social animals. Migration, seeking for food and fighting with enemies are social behaviors of animals. Optimization principle is seen in these animals. The Artificial Fish Swarm Optimization (AFSA) method is one of the Swarm Intelligence approaches that works based on the population and

Mehdi Neshat, Ali Adeli, Ghodrat Sepidnam, Mehdi Sargolzaei, Adel Najaran Toosi

International Journal on Smart Sensing and Intelligent Systems , ISSUE 1, 108–148

Research paper

Long-term behavioral, histological, biochemical and hematological evaluations of amyloid beta-induced Alzheimer’s disease in rat

(surgery without injection Aβ), and experimental group (two-sided intrahippocampal amyloid-beta injection into hippocampus). From each group, three animals were investigated 42 days after injection, and the remaining four animals were studied after one year. All animals were tested for learning abilities and memory. Finally, samples from blood, brain, heart, kidney, liver, colon and spleen were examined. In the experimental group, the size of amyloid plaques were increased significantly after one year

Raheleh Kheirbakhsh, Mahnaz Haddadi, Ahad Muhammadnejad, Alireza Abdollahi, Farshad Shahi, Behzad Amanpour-Gharaei, Azadeh Abrahim-Habibi, Tahereh Barati, Saeid Amanpour

Acta Neurobiologiae Experimentalis , ISSUE 1, 51–59

Research paper

Antimuscarinic-induced convulsions in fasted mice after food intake: no evidence of spontaneous seizures, behavioral changes or neuronal damage

Prolonged or repeated seizures have been shown to cause spontaneous recurrent seizures, increased anxiety-related behavior, locomotor hyperactivity, impaired functions of learning and memory, and neuronal damage in the hippocampus and other brain regions in animals. Mice and rats treated with antimuscarinic drugs after fasting for two days or less develop convulsions after being allowed to eat ad libitum. To address whether such behavioral and neuroanatomic changes occur following these

Nurhan Enginar, Asiye Nurten, Aslı Zengin Türkmen, Gül İpek Gündoğan, Zeynep Güneş Özünal

Acta Neurobiologiae Experimentalis , ISSUE 4, 373–381


Temporal specificity of latent inhibition in rats with daily water restriction prior to taste conditioning

stimulus used (Yamamoto and Yuyama, 1987; Mark et al., 1991; Yamamoto, 1993; Yamamoto et al., 1994; Heyer et al., 2004; Smith et al., 2004). Temporal specificity of LI of CTA has been demonstrated using saline as a CS (Manrique et al., 2004; Molero et al., 2008; Molero-Chamizo, 2013; 2017; 2018). Therefore, the inclusion of different taste stimuli as a CS might be another important procedural element for inducing temporal specificity. Restriction of the amount of different fluids consumed by animals

Andrés Molero-Chamizo, Guadalupe Nathzidy Rivera-Urbina

Acta Neurobiologiae Experimentalis , ISSUE 2, 99–107

Research paper

Effects of social stress and clomipramine on emotional memory in mice

We have previously observed impairing effects of social defeat stress (CSDS) on inhibitory avoidance (IA) in mice. Given the similarity between changes produced by social stress in animals and symptoms of certain human psychopathologies such as depression and anxiety, the effects of the antidepressant clomipramine on IA impairment produced by CSDS were evaluated in the present study. Male CD1 mice were randomly assigned to the groups: non-stressed+saline, non-stressed+clomipramine, stressed

Aranzazu Duque, Concepción Vinader-Caerols, Santiago Monleón

Acta Neurobiologiae Experimentalis , ISSUE 3, 225–233


Physical activity and environmental enrichment: Behavioural effects of exposure to different housing conditions in mice

with mice and rats suggest that animals usually show an improvement in the ability to learn both spatial and non-spatial tasks (Leggio et al., 2005; Diniz et al., 2010; Viola et al., 2010), faster adaptation to novel environments (Zimmermann et al., 2001; Hughes and Collins, 2010), and diminished exploratory behaviour (Mesa-Gresa et al., 2013b) following exposure to an enriched environment. Furthermore, exposure to enriched environments may also have beneficial effects on behavioural recuperation

Raisa Rabadán, Marta Ramos-Campos, Rosa Redolat, Patricia Mesa-Gresa

Acta Neurobiologiae Experimentalis , ISSUE 4, 374–385


Modulation of catalase, copper and zinc in the hippocampus and the prefrontal cortex in social isolation-induced depression in male rats

) in standard small polycarbonate cages (27×15×21 cm) or together (socialized) in large (42×15×21 cm) polycarbonate cages. Animals had free access to food and water. Animals were housed in a temperature- (22±1°C) and humidity-controlled (40-70%) environment with a 12 h light/dark cycle (lights on at 7:00 a.m.). All behavioral assessments were conducted during the light phase of the cycle (specifically, from 11:00 a.m. to 3:00 p.m.) in the experimental room. All rats were habituated to the animal

Hamidreza Famitafreshi, Morteza Karimian

Acta Neurobiologiae Experimentalis , ISSUE 2, 184–192

Research paper

Effects of different delayed exercise regimens on cognitive performance in fimbria-fornix transected rats

administered as interval training of short (3x5 min) duration (FS-SI), iv) forced swimming exercise administered as interval training of long (3x15 min) duration (FS-LI), v) forced swimming exercise administered as one session of short (5 min) duration (FS-SS), and vi) forced swimming exercise administered as one session of long (15 min) duration (FS-LS). The exercise was initiated 21 days post-surgery. Subsequently, all animals were administered 28 acquisition sessions in an 8-arm radial maze. Both sham

Elise Wogensen, Linda Marschner, Marie Gajhede Gram, Siri Mehlsen, Valdemar H. B. Uhre, Pernille Bülow, Jesper Mogensen, Hana Malá

Acta Neurobiologiae Experimentalis , ISSUE 4, 323–336

Research paper

Fos immunoreactivity in the intermediolateral nucleus induced by tendon vibration of the m. triceps surae in rats pretreated with a nitric oxide blocker or precursor

). The T5/T13 segments in tendon-vibrated +7-NI animals showed the highest increase of Fos-immunoreactive neurons. This increase was two times higher than that in tendon only-vibrated control rats and tendon-vibrated + LA animals. The highest mean number of labelled neurons were observed in the IML nucleus and in layers 4 and 7 of the T5-L3 segments in tendon-vibrated and tendon-vibrated + 7-NI animals, and in the IML nucleus and layer 4 in tendon-vibrated + LA rats. The highest mean number of

Inna V. Vereshchaka, Andriy V. Maznychenko, Olena P. Mankivska, Volodymyr O. Maisky, Oleh V. Vlasenko, Olexandr V. Dovgan, Olga L. Ocheretna, Tomasz Tomiak, Alexander I. Kostyukov

Acta Neurobiologiae Experimentalis , ISSUE 2, 82–91

Research paper

Detrimental effects of chia (Salvia hispanica L.) seeds on learning and memory in aluminum chloride-induced experimental Alzheimer’s disease

Polyphenols and omega-3 fatty acids are thought to have beneficial effects in Alzheimer’s disease, the most common cause of dementia. Seeds of chia (Salvia hispanica L.) are highly rich in these nutrients, and thus, the present study investigated the effects of chia seeds on behavior and cognition in an aluminum-induced Alzheimer’s disease model in rats. Experimental animals received chia supplementation either during the generation of the model (i.e., pretreatment) or after the model was

Yasemin Bilgic, Enver Ahmet Demir, Nilufer Bilgic, Hatice Dogan, Okan Tutuk, Cemil Tumer

Acta Neurobiologiae Experimentalis , ISSUE 4, 322–331


Stimulus-seeking in rats is accompanied by increased c-Fos expression in hippocampal CA1 as well as short 22 kHz and flat 50 kHz calls

was followed by 3 habituation sessions wherein rats were placed individually in the self-exposure chamber for 30 min per day for 3 consecutive days. The following day, during the test/self-exposure session, the rats were assigned to two groups and placed again in the self-exposure chamber for 30 min. For experimental rats (n=10), activation of any photocell, performed during light-on, shut down the light for 5 s. Yoked (control, n=10) animals, in contrast, were unable to switch off the light

Ita Robakiewicz, Monika Polak, Małgorzata Rawska, Dominik Alberski, Rafał Polowy, Kinga Wytrychiewicz, Mateusz Syperek, Jan Matysiak, Robert K. Filipkowski

Acta Neurobiologiae Experimentalis , ISSUE 3, 310–318

Original Paper

Drug Susceptibility of Non-tuberculous Strains of Mycobacterium Isolated from Birds from Poland

Abstract Mycobacterioses are a constant problem in backyard poultry, as well as pet birds. To date, no evidence of direct transmission of atypical bacilli between humans has been demonstrated, but it cannot be ruled out that sick animals can be a source of infection for people in their environment. The aim of the study was to identify mycobacteria isolated from birds with diagnosed mycobacteriosis and to determine the susceptibility of mycobacterial isolates from these animals to


Polish Journal of Microbiology , ISSUE 4, 487–492

Research Article


In recent years, there have been notable increas in the occurrence of emerging and reemerging infectious diseases. Most have resulted from the crossing of species barriers from animals to humans, especially from wildlife reservoirs. These threats draw attention to the changing patterns of diseases on a global scale and raise the need for a new worldwide strategy for expanding interdisciplinary collaborations and communications in all aspects of health care for humans, animals and the

Marian Binek, Magdalena Kizerwetter-Świda, Dorota Chrobak-Chmiel

Postępy Mikrobiologii - Advancements of Microbiology , ISSUE 2, 95–105

Research Article

Novel Application of Kinect Sensor for Children to Learn Paleontological Environment

The authors are developing a simulation-based environmental learning support system using Kinect sensors. Obviously, it is impossible for learners to experience the actual paleontological environment, and it is therefore difficult for them to learn about the environments and lives. Then, we proposed an immersive animation display system using Kinect sensors and their human skeleton-tracking function. The system animates paleontological animals and their environment on the screen and displays

Tomohiro Nakayama, Takahiro Nakadai, Ryuichi Yoshida, Takeki Ogitsu, Hiroshi Takemura, Hiroshi Mizoguchi, Kaori Izuishi, Fusako Kusunoki, Keita Muratsu, Shigenori Inagaki

International Journal on Smart Sensing and Intelligent Systems , ISSUE 5, 1–4

Research paper

Tiapride prevents the aversive but not the rewarding effect induced by parabrachial electrical stimulation in a place preference task

The parabrachial complex has been related to the processing of both rewarding and aversive signals. This pontine area is activated after the gastrointestinal administration of rewarding nutrients, in taste aversion learning, and in response to the reinforcing and aversive effects of some drugs of abuse. Electrical stimulation of this region can induce, in different animals, preference or aversion behaviors towards a place in a rectangular three-chamber maze task. This study examined the effect

María M. Hurtado, Raquel García, Amadeo Puerto

Acta Neurobiologiae Experimentalis , ISSUE 3, 236–243

Short Communication

In vivo stimulation of locus coeruleus: effects on amygdala subnuclei

functional connectivity between the LC and the amygdala subnuclei. To reach this objective, we evaluated c-fos immunoreactive cells in amygdala nuclei following direct electrical stimulation of the LC in conscious animals. This analysis of c-fos immunoreactivity could inform whether there are differences in activity of the amygdala subnuclei related to LC electrical stimulation in conscious animals. Our results showed a marked increase in c-fos activity in these amygdala subnuclei both ipsilateral and

Elisa Rodríguez-Ortega, Fernando Cañadas, Francisca Carvajal, Diana Cardona

Acta Neurobiologiae Experimentalis , ISSUE 3, 261–268


Increased short-term food intake after external lateral parabrachial subnucleus lesions in rats

et al., 2001a; b). This information appears to be processed and sent to the brain via the vagal pathway (Mei, 1983; Cervero, 1994; Sengupta and Gebhart, 1994) and has frequently been related to the regulation of short-term food intake (Deutsch, 1985; Phillips and Powley, 1996, 1998; Powley and Phillips, 2004; Berthoud 2008). Previously published results indicate that animals with vagal deafferentation would have larger initial intakes on their first exposures to food because they lack the

Antonio D.R. Agüera, María A. Zafra, Filomena Molina, Amadeo Puerto

Acta Neurobiologiae Experimentalis , ISSUE 1, 101–111

Research Article

Sensor Technology For Animal Health Monitoring

the area of automated animal health monitoring. In this research, we have identified specific diseases which are common in dairy animals which can be identified through the use of non-invasive, low-cost, sensor technology. These diseases have been mapped to specific aspects of animal behaviour that have been mapped to the three sensors which are most significant to identify these diseases. The identified sensors will be shown to be vital in the development of the next generation of health

Amruta Helwatkar, Daniel Riordan, Joseph Walsh

International Journal on Smart Sensing and Intelligent Systems , ISSUE 5, 1–6

Mini Review

Bacteriological, Clinical and Virulence Aspects of Aeromonas-associated Diseases in Humans

Aeromonads have been isolated from varied environmental sources such as polluted and drinking water, as well as from tissues and body fluids of cold and warm-blooded animals. A phenotypically and genotypically heterogenous bacteria, aeromonads can be successfully identified by ribotyping and/or by analysing gyrB gene sequence, apart from classical biochemical characterization. Aeromonads are known to cause scepticemia in aquatic organisms, gastroenteritis and extraintestinal diseases such as


Polish Journal of Microbiology , ISSUE 2, –

Research paper

Anhedonia but not passive floating is an indicator of depressive‑like behavior in two chronic stress paradigms

Depression is the most common form of mental disability in the world. Depressive episodes may be precipitated by severe acute stressful events or by mild chronic stressors. Studies on the mechanisms of depression require both appropriate experimental models (most of them based on the exposure of animals to chronic stressors), and appropriate tests for assessment of depressive states. In this study male Wistar rats were exposed to two different chronic stress paradigms: an eight‑week chronic

Mikhail Yu. Stepanichev, Anna O. Tishkina, Margarita R. Novikova, Irina P. Levshina, Sofiya V. Freiman, Mikhail V. Onufriev, Olga A. Levchenko, Natalia A. Lazareva, Natalia V. Gulyaeva

Acta Neurobiologiae Experimentalis , ISSUE 4, 324–333

Research paper

Effects of individual stressors used in a battery of “chronic unpredictable stress” on long-term plasticity in the hippocampus of juvenile rats

We have studied alterations in the properties of long-term potentiation (LTP) in hippocampal slices of juvenile rats induced by the exposure of animals to different individual stressors usually used in batteries of chronic unpredictable stress (CUS), a widely used model of depression. Social isolation for 16 h did substantially affect neither the magnitude and nor the development of LTP. The effects of stroboscopic illumination and water deprivation appeared most severe, though opposite: the

Alexandra A. Gorbunova, Irina V. Kudryashova, Anna O. Manolova, Margarita R. Novikova, Mikhail Yu. Stepanichev, Natalia V. Gulyaeva

Acta Neurobiologiae Experimentalis , ISSUE 3, 244–253



1. Introduction Dermatomycoses are skin diseases caused by an infection of its surface layers and other keratinized structures such as hair and nails by fungi referred to as dermatophytes [106]. Based on their adaptation to life, these eukaryotic microorganisms may be divided into three groups: those that attack people, referred to as anthropophilic, those associated with animals – zoophilic and those that live in the soil – geophilic ones [35, 44]. Dermatophytes belong to eurybiotic organisms

Dominik Łagowski, Sebastian Gnat, Aneta Nowakiewicz, Marcelina Osińska, Przemysław Zięba

Postępy Mikrobiologii - Advancements of Microbiology , ISSUE 2, 165–176

Research paper

Long-term consumption of fermented rooibos herbal tea offers neuroprotection against ischemic brain injury in rats

adult male Wistar rats. FRHT was administered to the animals ad libitum for 7 weeks prior to the induction of ischemic injury via a 20-minute bilateral occlusion of the common carotid arteries (BCCAO) followed by reperfusion for 24, 96 and 168 hours respectively. Neurobehavioural deficits, brain oedema, blood-brain barrier (BBB) damage, apoptosis, lipid peroxidation and total antioxidant capacity were subsequently evaluated using standard methods. Our results showed that long-term consumption of

Olusiji Akinrinmade, Sylvester Omoruyi, Daneel Dietrich, Okobi Ekpo

Acta Neurobiologiae Experimentalis , ISSUE 1, 94–105

Research paper

Continuous MPTP intoxication in the Göttingen minipig results in chronic parkinsonian deficits

of the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Twelve female Göttingen minipigs were divided into groups of 2–4 animals and implanted with infusion pumps for continuous intramuscular MPTP delivery of 4–24 mg MPTP/day for 11 weeks. The animals showed parkinsonian symptoms with bradykinesia, rigidity, coordination and chewing difficulties. Symptoms were stable in the 12 and 18 mg MPTP/day groups, whereas the remaining groups showed partial or full behavioral recovery

Mette Slot Nielsen, Andreas Nørgaard Glud, Arne Møller, Poul Mogensen, Dirk Bender, Jens Christian Sørensen, Doris Doudet, Carsten Reidies Bjarkam

Acta Neurobiologiae Experimentalis , ISSUE 3, 199–211


Selective neuronal death following exposure to methylenedioxypyrovalerone is accompanied by an inhibition of NMDA receptor NR2B subunit expression

drugs may have important consequences and warrants investigation. METHODS Animals BALB/c mice were mated in the animal facility of the Department of Anatomy, Histology and Embryology. Pregnant females were housed individually under standard laboratory conditions (12 hours dark/12 hours light cycle) with food and water available ad libitum. Seven pregnant dams were used for the NMDA receptor analysis, and a further 2 for obtaining neural tube explants (see below). From the 7 litters altogether 50

László István Gerecsei, Tamás Balázsa, Diego Echevarría, Ágota Ádám, Gergely Zachar, András Csillag

Acta Neurobiologiae Experimentalis , ISSUE 1, 92–100



This paper proposes a simulation-based environmental learning support system, based on Kinect sensors, which is currently under development. Our system animates paleontological animals and their habitats on a display in synchronization with learners’ actions, immersing learners in a real-life paleontological environment. We evaluated the system by recording real-time measurements of learners’ movements, and controlled the animation based on sensor output. Participants were subsequently

T. Nakayama, R. Yoshida, T. Nakadai, T. Ogitsu, H. Mizoguchi, K. Izuishi, F. Kusunoki, K. Muratsu, R. Egusa, S. Inagaki

International Journal on Smart Sensing and Intelligent Systems , ISSUE 2, 1050–1062


Using TTouch to Reduce Stress and Enhance Learning when Training Guide Dogs

Excessive stress impairs learning. The Tellington TTouch method (TTouch) is used to reduce stress and relax animals so they can learn more effectively. It aims at increasing an animal’s body awareness and balance by using a combination of techniques that include specific touches, body wraps, and leading (movement) exercises. This article introduces the TTouch method, its role in sensory enhanced learning, and provides a review of TTouch in the scientific literature and the way this

Janice Lloyd, Elizabeth (Lib) Roe

International Journal of Orientation & Mobility , ISSUE 1, 8–20

Research Article


Francisella tularensis is an intracellular bacterial pathogen which causes a potentially lethal disease named tularemia. Some studies have been conducted to describe and identify the virulence factors of F. tularensis. This pathogen is able to infect a variety of cells of various hosts, including wild animals, especially rabbits, hares and rodents, and humans. This may suggest that genes of F. tularensis must adapt to many different intraorganismal environments. Still, little is known about the

Kamila Formińska, Aleksandra Anna Zasada

Postępy Mikrobiologii - Advancements of Microbiology , ISSUE 2, 187–195


Intracerebroventricular streptozotocin induces behavioral impairments and increases short-term C3 gene expression in the hippocampus of Wistar rats

late (4 months after icv-STZ) expression. METHODS Thirty-two male Wistar rats at the age of 90 days, weighing in average 350 g, were used in this study. The animals were obtained from the animal facility at the Universidade Positivo and remained under controlled conditions including light/dark cycle of 12 h (07:00 am to 07:00 pm) and temperature of 21°C with water and food ad libitum. The animals were divided into four groups of eight rats each (n=8 per group) and housed into subgroups of four

Gabrielle Pfutzenreuter, Kenny Nieradka, Márcia Regina Pincerati, Ilton Santos da Silva

Acta Neurobiologiae Experimentalis , ISSUE 2, 160–169

Research Article

Automated Monitoring of Foraging Behaviour in Free Ranging Sheep Grazing a Bio-diverse Pasture using Audio and Video Information

Non-invasive methods for monitoring foraging choice in free ranging grazing animals are largely limited to accelerometers and video calibration. Acoustic data from a wireless microphone attached to the skull has been used to distinguish between resting and feeding bouts in free ranging cattle, sheep and goats. Similar data has been reported in restrained sheep presented with forage of differing dry matter content.  We take these approaches further by using a small video camera attached to

J. Sneddon, A. Mason

International Journal on Smart Sensing and Intelligent Systems , ISSUE 5, 1–4



Anna Kisiel, Katarzyna Jęckowska

Postępy Mikrobiologii - Advancements of Microbiology , ISSUE 3, 317–327



infections in humans, e.g. infections of the urinary ract, blood, wounds and other. In addition to the non-pathogenic strains of E. coli that colonize the human intestine, a large group of strains is pathogenic to humans and animals [18, 61]. Pathogenic E. coli rods include strains associated with infections of the digestive tract, as well as strains which cause extrainetstinal infections. E. coli strains responsible for intestinal infections are divided into the following pathovars depending on the

Michał Turniak, Beata Sobieszczańska

Postępy Mikrobiologii - Advancements of Microbiology , ISSUE 2, 143–152

Research Article


The Orthomyxoviruses is a family of viruses with its most common representatives being the influenza viruses (A, B, C and D types), which constitute a significant clinical problem. Influenza is a disease affecting animals and people. It is transmitted by airborne droplets and manifestes itself with such symptoms as coughing, sneezing, muscle pain or fever. Influenza often leads to complications, including pneumonia and myocarditis. In the past, influenza viruses were responsible for pandemics

Michał Wiciński, Kamil Leis, Bartosz Malinowski, Mateusz Maciej Węclewicz, Elżbieta Grześk, Grzegorz Grześk

Postępy Mikrobiologii - Advancements of Microbiology , ISSUE 2, 138–144


Functional organization of the human amygdala in appetitive learning

The amygdala is a small subcortical structure located bilaterally in medial temporal lobes. It is a key region for emotional processes and some forms of associative learning. In particular, the role of the amygdala in processing of negative emotions and aversive learning has been shown in numerous studies. However, involvement of this structure in processing of positive affect and appetitive learning is not fully understood. Previous experiments in animals are not consistent. While some authors

Emilia Kolada, Krzysztof Bielski, Marcel Falkiewicz, Iwona Szatkowska

Acta Neurobiologiae Experimentalis , ISSUE 2, 118–127

Mini Review

Brucella – Virulence Factors, Pathogenesis and Treatment

Brucellae are Gram-negative, small rods infecting mammals and capable of causing disease called brucellosis. The infection results in abortion and sterility in domestic animals (sheeps, pigs, rams etc). Especially dangerous for humans are: Brucella melitensis, Brucella suis, Brucella abortus, and Brucella canis that trigger unspecific symptoms (flu-like manifestation). Brucella rods are introduced via host cells, by inhalation, skin abrasions, ingestion or mucosal membranes. The most important


Polish Journal of Microbiology , ISSUE 2, 151–161


Presence of Antibodies Against Leptospira interrogans Serovar hardjo in Serum Samples from Cattle in Ukraine

Introduction Leptospirosis is a dangerous zoonotic infection with a worldwide distribution that is recognized as an emerging disease (Levett 2001; Sykes et al. 2011). There are no available data about leptospirosis in animals and humans in a number of countries, and thus its global burden remains mostly unknown (Hartskeerl et al. 2011). In general, leptospirosis has been reported in over 150 mammalian species (Ko et al. 2009), but the infectious agent can also be detected in other classes of


Polish Journal of Microbiology , ISSUE 3, 295–302

Research Article


The presence of Listeria rods, especially Listeria monocytogenes, in the environment and food products, contributes each year to death of both humans and animals. The ability of bacteria to lead a saprophytic and parasitic existence as well as insensitivity to many physicochemical factors greatly facilitates the spread and guarantees access to a wide range of vulnerable organisms. Although the factors predisposing to infection result in a relatively low incidence of disease, infections are

Monika Lewańska, Agnieszka Godela, Magdalena Myga-Nowak

Postępy Mikrobiologii - Advancements of Microbiology , ISSUE 2, 106–116


Forest fire detection using wireless sensor networks

Premsai Dasari, Gundam Krishna Jayanth Reddy, Abhishek Gudipalli

International Journal on Smart Sensing and Intelligent Systems , ISSUE 1, 1–8

Research Article


Outer membrane vesicles (OMVs) are extracellular structures produced by most gram‑negative bacteria, including pathogens of humans and animals. OMVs play an important role in the physiology of microorganisms and are an integral part of many biological processes. Following the discovery that they are able to transport many biomolecules, also these which have the ability to interact with the immune system, their potential use as non‑replicating vaccines has become an important aspect of

Joanna Jadwiga Klim, Renata Godlewska

Postępy Mikrobiologii - Advancements of Microbiology , ISSUE 1, 43–55

Research Article


. Mycobacterium spp., Leptospira spp. and aquatic bacteria are also found in turtles. Additionally, nematode transmissions from invasive turtles to the autochthonic ones have been described. Alien turtles were less affected by parasitic invasion than animals living in a native location, but the infestation of alien parasites in native turtle species was usually more severe. Reports on viral or fungal infections in turtles are scarce. The identified knowledge gaps justify the need for research which will

Olga Goławska, Magdalena Zając, Dariusz Wasyl, Marta Demkowska-Kutrzepa, Ewa Borzym, Paweł Różański, Artur Rzeżutka

Postępy Mikrobiologii - Advancements of Microbiology , ISSUE 2, 163–170


Unity and Division: Caring for Humans and Non-humans in a Divided Land

Introduction The island of Timor was divided in the late nineteenth century by the colonising forces of the Portuguese and the Dutch. The ensuing border has continuously separated the people of Koba Lima, an ancient coalition of five kingdoms straddling the international land border of Timor-Leste and Indonesia and has constrained relationships with their ancestral lands. In this context, the free co-existence and movement of Timor’s wild animals, plants and natural phenomena remain essential

Balthasar Kehi, Lisa Palmer

Borderlands , ISSUE 2, 64–84


Hypothermia in the course of acute traumatic spinal cord injury

minimal functional improvement. Other neuroprotective strategies such as therapeutic hypothermia alone or in combination with other interventions, whose mechanisms of action are multifactorial and may thereby protect nervous tissue and minimize overall loss of neurological function, are therefore being considered for experimental and clinical trials. Experimental animals used in SCI studies Although detailed descriptions of the causes and symptoms of traumatic SCI date back to ancient Egyptian times

Jozef Kafka, Nadezda Lukacova, Igor Sulla, Marcela Maloveska, Zuzana Vikartovska, Dasa Cizkova

Acta Neurobiologiae Experimentalis , ISSUE 2, 172–178


Assessment of Globodera pallida RNA Extracted from Solanum Roots

results once the animals entered their hosts’ roots. We have compared several extraction procedures to ascertain whether a single protocol was capable of recovering high-quality, high-molecular-weight RNA from newly hatched J2 larva as well as from larva embedded in roots of both potatoes (Solanum tuberosum L. cv. Desiree) and a very distantly related species, Solanum sisymbriifolium. Although it was possible to recover large amounts of RNA from J2 larvae using Proteinase K


Journal of Nematology , ISSUE 1, 12–20

Research Article

Morphological Re-Description and 18 S rDNA Sequence Confirmation of the Pinworm Aspiculuris tetraptera (Nematoda, Heteroxynematidae) Infecting the Laboratory Mice Mus musculus

Aspiculuris tetraptera is a heteroxynematid nematoda infecting most of the laboratory animals, occasionally mice which represent the mostly used animal for biological, medical, and pharmacological studies. The present study aimed to investigate the prevalence of nematode parasites infection in the laboratory mice Mus musculus in Egypt. Morphologically, this oxyurid possessed four distinct cephalic papillae on a cephalic plate, with three small rudimental lips carrying two sessile poorly

Rewaida Abdel-Gaber, Fathy Abdel-Ghaffar, Saleh Al Quraishy, Kareem Morsy, Rehab Saleh, Heinz Mehlhorn

Journal of Nematology , ISSUE 2, 117–132

Research paper

Marble burying as compulsive behaviors in male and female mice

Marble burying is considered an, albeit controversial, animal model of the compulsive like behaviors of obsessive-compulsive disorder (OCD). Hallmark features of OCD patients are similarities and, more prominent, differences from anxiety disorders, e.g., the absence of sex differences and resistance to spontaneous remission. We report an experiment on marble burying by male and female C57/BL6/N mice. Animals were administered either the classic anxiolytic drug, diazepam, that targets the GABA

George T. Taylor, Sandra Lerch, Sabine Chourbaji

Acta Neurobiologiae Experimentalis , ISSUE 3, 254–260

Research paper

Anti-inflammatory compound curcumin and mesenchymal stem cells in the treatment of spinal cord injury in rats

studied, two groups received curcumin on the surface of the spinal cord immediately after SCI and then once a week for 3 weeks together with an intraperitoneal daily curcumin injection for 28 days. The other two groups received saline. Seven days after SCI, human MSC were intrathecally implanted in one curcumin and one saline group. Both curcumin and curcumin combined with MSC treatment improved locomotor ability in comparison to the saline treated animals. The combined treatment group showed

Jiri Ruzicka, Lucia Machova Urdzikova, Anna Kloudova, Anubhav G. Amin, Jana Vallova, Sarka Kubinova, Meic H. Schmidt, Meena Jhanwar-Uniyal, Pavla Jendelova

Acta Neurobiologiae Experimentalis , ISSUE 4, 358–374

Research paper

Testosterone enhancement during pregnancy influences social coping and gene expression of oxytocin and vasopressin in the brain of adult rats

compared to controls. However, we did not observe any sex differences in the expression of oxytocin and arginine-vasopressin mRNA in these regions. Our findings show that testosterone enhancement in pregnancy could have long-lasting effects on oxytocin and arginine-vasopressin levels in the brain of adult animals, but lead to changes in behavioral aspects of coping strategies only in males.

Zuzana Dzirbíková, Alžbeta Talarovičová, Peter Štefánik, Lucia Olexová, Lucia Kršková

Acta Neurobiologiae Experimentalis , ISSUE 3, 264–270


Neuroprotective effects of lipopolysaccharide and naltrexone co-preconditioning in the photothrombotic model of unilateral selective hippocampal ischemia in rat

protective effect of LPS and NTX preconditioning against an ischemic attack we established co-preconditioning of these two agents in the photothrombotic model of unilateral selective hippocampal ischemia in rat. METHODS Animals Male albino Wistar strain rats (250±25 g mean body weight; 10 weeks of age) were purchased from the Faculty of Pharmacy, Shahid Beheshti University of Medical Science, Tehran, Iran. All animal groups were housed in Plexiglas cages until surgery, were given ad libitum access to

Sayed Masoud Hosseini, Alireza Golaghaei, Ehsan Nassireslami, Nima Naderi, Hamid Gholami Pourbadie, Milad Rahimzadegan, Saeid Mohammadi

Acta Neurobiologiae Experimentalis , ISSUE 1, 73–85

Research Article


variable intergenic regions may be also applicable to detection, differentiation and determination of genetic variation among F. tularensis strains. In addition, the above methods could be successfully used in molecular characterization of tularaemia strains from humans and animals isolated in screening research, and during epizootic and epidemic outbreaks.

Piotr Cieślik, Józef Knap, Agata Bielawska-Drózd

Postępy Mikrobiologii - Advancements of Microbiology , ISSUE 1, 58–67

Research paper

Interaction between urethane and cannabinoid CB1 receptor agonist and antagonist in penicillin-induced epileptiform activity

intracerebroventricularly 30 minutes after the penicillin application in urethane-anesthetized and conscious animals. Urethane completely eliminated spontaneous ictal events in ECoG recordings and reduced the frequency and total amount of epileptiform activity. It did not alter either the proconvulsant effects of AM-251 or the anticonvulsant effects of ACEA on penicillin-induced epileptiform activity. The electrophysiological evidence suggests that there is no possible interaction between urethane and cannabinoid CB1

Gokhan Arslan, Sabiha Kubra Alici, Mustafa Ayyildiz, Erdal Agar

Acta Neurobiologiae Experimentalis , ISSUE 2, 128–136

Research Article


Staphylococci are pathogenic bacteria often isolated from clinical material obtained from animals. Unlike in human medicine, in veterinary sciences various species of coagulase-positive staphylococci have been isolated from clinical specimens. In addition to Staphylococcus aureus and Staphylococcus pseudintermedius, other species are also often identified. Recently, the taxonomy of staphylococci has been updated, therefore, it is now important to recognize also the new species. Currently

Magdalena Kizerwetter-Świda, Dorota Chrobak-Chmiel, Magdalena Rzewuska

Postępy Mikrobiologii - Advancements of Microbiology , ISSUE 3, 270–277

Research Article


, which significantly interferes with a sense of security and restricts the freedom of human activities. Currently, biological terrorism is a global threat associated with the use of weapons for political or religious reasons. The threat from radical religious fundamentalists is particularly dangerous. The most common biological threat agents are microorganisms causing zoonoses, i.e. diseases which can be transmitted from animals to humans. The most dangerous are Bacillus anthracis, Yersinia pestis

Karol Abramczyk, Anna Gałązka

Postępy Mikrobiologii - Advancements of Microbiology , ISSUE 4, 395–404

Research paper

High-dose 1,25-dihydroxyvitamin D supplementation elongates the lifespan of Huntington’s disease transgenic mice

a transgenic mouse model of Huntington’s disease. Methods: Our study was performed on N171-82Q Huntington’s disease transgenic mice in age- and gender-matched groups. We collected data on the motor state and survival of the mice. Results: The results demonstrate that though vitamin D3 had no effect on the motor performance of transgenic mice, but significantly increased the lifespan of transgenic animals (Kaplan-Meier survival curves: vehicle-supplemented group

Máté` Fort Molnár, Rita Török, Evelin Sümegi, László Vécsei, Péter Klivényi, Levente Szalárdy1

Acta Neurobiologiae Experimentalis , ISSUE 3, 176–181


Roux-en-Y gastric bypass surgery triggers rapid DNA fragmentation in vagal afferent neurons in rats

are expressed early after injury (Shortland et al., 2006; Czaja et al., 2008), we aimed to evaluate neuronal damage in vagal afferent gut-brain connection 24 h after RYGB surgery. METHODS Animals Sprague-Dawley male (n=25; 300g) and female rats (n=20; 250 g; Envigo, Indianapolis, IN) were housed individually in conventional polycarbonate shoe-box cages in a temperature-controlled vivarium with ad libitum access to standard pellets of rat chow (PicoLab rodent diet 20, product #5053, Fort Worth

Dulce M. Minaya, Patricia M. Di Lorenzo, Andras Hajnal, Krzysztof Czaja

Acta Neurobiologiae Experimentalis , ISSUE 4, 432–444


Local field potential power spectra and locomotor activity following treatment with pseudoephedrine in mice

exploratory behaviors. Morphine was used as a standard drug. Animals were implanted with an intracranial electrode in the striatum, for LFP signal recording. Animal movement was monitored by a web-based camera. The tested hypothesis was that a 15 mg/kg morphine dose would clearly alter LFP oscillations, whereas PSE (at doses of 50 and 100 mg/kg oral) would not. METHODS Animal models Male Swiss albino ICR mice (25–45g) were supplied by the Southern Laboratory Animal Facility of Prince of Songkla

Nusaib Sa-ih, Chayaporn Reakkamnuan, Nifareeda Samerphob, Dania Cheaha, Saree Niyomdecha, Ekkasit Kumarnsit

Acta Neurobiologiae Experimentalis , ISSUE 1, 19–31

Research paper

Impact of recurrent hypoglycemic stress on hindbrain A2 nerve cell energy metabolism and catecholamine biosynthesis: modulation by estradiol

(DβH) and rate-limiting energy pathway enzyme protein expression. Precedent hypoglycemia respectively decreased or increased baseline DβH expression in estradiol- (E) vs. oil (O)-treated rats; this protein profile was further suppressed or augmented in those animals at 2 hr after re-induction of hypoglycemia. These data suggest that estradiol may curtail A2 noradrenergic-controlled functions both in the midst of and between hypoglycemic bouts. Results also show that prior hypoglycemia exposure

Pratistha Tamrakar, Karen P. Briski

Acta Neurobiologiae Experimentalis , ISSUE 1, 31–44

Research paper

Energy-dense diet triggers changes in gut microbiota, reorganization of gut-brain vagal communication and increases body fat accumulation

different bacteria strains to determine neurotoxicity. HFD altered gut microbiota with increases in Firmicutes/Bacteriodetes ratio and in pro-inflammatory Proteobacteria proliferation. HFD triggered reorganization of vagal afferents and microglia activation in the NTS, associated with weight gain. Minocycline-treated HFD rats exhibited microbiota profile comparable to LFD animals. Minocycline suppressed HFD-induced reorganization of vagal afferents and microglia activation in the NTS, and reduced body

Alexandra C. Vaughn, Erin M. Cooper, Patricia M. DiLorenzo, Levi J. O’Loughlin, Michael E. Konkel, James H. Peters, Andras Hajnal, Tanusree Sen, Sun Hye Lee, Claire B. de La Serre, Krzysztof Czaja

Acta Neurobiologiae Experimentalis , ISSUE 1, 18–30

Research paper

Nucleus accumbens local field potential power spectrums, phase-amplitude couplings and coherences following morphine treatment

Hz) gamma powers in the NAc following morphine administration (5 and 15 mg/kg, i.p.). These gamma activities oscillated independently with different time-course responses. Locomotor activity was also significantly increased by morphine administration. Regression analyses revealed that high gamma activity induced by morphine was positively correlated with distance travelled by animals. Low and high gamma powers were completely abolished by injection of naloxone, a non-specific opiate antagonist

Chayaporn Reakkamnuan, Dania Cheaha, Ekkasit Kumarnsit

Acta Neurobiologiae Experimentalis , ISSUE 3, 214–224

Research paper

Additive and antagonistic antinociceptive interactions between magnesium sulfate and ketamine in the rat formalin test

Because ketamine and magnesium block NMDA receptor activation by distinct mechanisms of action, we hypothesized that in a model of inflammatory pain in rats the combination of ketamine and magnesium might be more effective than ketamine alone. Antinociceptive activity was assessed by the formalin test in male Wistar rats (200–250 g). Animals were injected with 100 μL of 2.5% formalin to the plantar surface of the right hind paw. Data were recorded as the total time spent in pain-related

Katarina Savić Vujović, Sonja Vučković, Dolika Vasović, Branislava Medić, Nick Knežević, Milica Prostran

Acta Neurobiologiae Experimentalis , ISSUE 2, 137–146

Original Research

Optimization of Mixed Solid-state Fermentation of Soybean Meal by Lactobacillus Species and Clostridium butyricum

Soybean meal is the main vegetable protein source in animal feed. Soybean meal contains several anti-nutritional factors, which directly affect digestion and absorption of soy protein, thereby reducing growth performance and value in animals. Fermented soybean meal is rich in probiotics and functional metabolites, which facilitates soybean protein digestion, absorption and utilization in piglets. However, the mixed solid-state fermentation (SSF) conditions of soybean meal remain to be optimized


Polish Journal of Microbiology , ISSUE 3, 297–305


Behavioral verification of associative learning in whisker-related fear conditioning in mice

, called minifreezing, resembles the frequently used behavioral measure known as the freezing response. However, this is only applicable for freely moving animals. This article will review experimental evidence confirming that minifreezing is a relevant index of association formation between the neutral CS and aversive UCS.

Anita Cybulska-Kłosowicz

Acta Neurobiologiae Experimentalis , ISSUE 2, 87–97

Original Paper

The Emergence of Different Functionally Equivalent PAH Degrading Microbial Communities from a Single Soil in Liquid PAH Enrichment Cultures and Soil Microcosms Receiving PAHs with and without Bioaugmentation

Polycyclic aromatic hydrocarbon (PAHs) are common soil contaminants of concern due to their toxicity toward plants, animals and microorganisms. The use of indigenous or added microbes (bioaugmentation) is commonly used for bioremediation of PAHs. In this work, the biodegradation rates and changes in the bacterial community structure were evaluated. The enrichment culture was useful for unambiguously identifying members of the soil bacterial community associated with PAH degradation and yielded


Polish Journal of Microbiology , ISSUE 3, 365–375

Research paper

Pharmacokinetics and pharmacodynamics of a novel Acetylcholinesterase Inhibitor, DMNG-3

had a positive effect of improvement of learning and memory in mice in passive avoidance tests. The elimination half-life (T1/2) was 14.07±1.29, 15.87±1.03 h, and the total clearance (CL) values were 0.70±0.11, 0.78±0.13 L/h/kg, respectively. The pharmacokinetic studies showed that DMNG-3 has a slowly clearance and large distribution volume in experimental animals, and its disposition is linear over the range of doses tested. The liver, small intestine, stomach, and large intestine were the major

Xin-Guo Zhang, Fei Kou, Guo-Di MA, Peng Tang, Zhong-Duo Yang

Acta Neurobiologiae Experimentalis , ISSUE 2, 117–124

Research paper

BDNF expression in cat striate cortex is regulated by binocular pattern deprivation

months (2BD, 4BD, 6BD), and late onset BD for 2 months upon 2 months of normal vision (2N2BD), as animal models of congenital and delayed onset cataract. During normal cortical development the BDNF transcript levels, measured by quantitative RT-PCR, remained stable. Higher BDNF mRNA levels were found in central area 17 of 2BD and 6BD animals compared to age-matched controls. In central area 17, the high BDNF mRNA levels at the end of the BD period may activate a mechanism by which plastic processes

Karolina Laskowska-Macios, Lutgarde Arckens, Małgorzata Kossut, Kalina Burnat

Acta Neurobiologiae Experimentalis , ISSUE 3, 199–204

Research paper

Potential role of dopamine transporter in behavioral flexibility

cognitive processes. Here we used a gene knockout mouse model to investigate the role of DAT in the performance on the Attentional Set-Shifting Task (ASST) stages dependent upon the OFC and the DMS. Additionally, behavior of mice after repeated administration of selective DAT inhibitor, GBR 12909, was examined. The animals were treated with the inhibitor to elicit a compensatory DAT up-regulation following withdrawal. Learning was slower and the number of errors during reversal learning and intra

Anita Cybulska-Klosowicz, Julia Dabrowska, Sebastian Niedzielec, Renata Zakrzewska, Aleksandra Rozycka

Acta Neurobiologiae Experimentalis , ISSUE 2, 176–189

Research paper

Antiallodynic effect of intrathecal resiniferatoxin on neuropathic pain model of chronic constriction injury

neuropathic pain or epidurally and topically to produce prolonged analgesic effects. However, the use of RTX is controversial because its neurotoxicity and margin of safety have not been addressed adequately. The present study evaluates the effect of intrathecal RTX on the induction and allodynia behavior of animals submitted to neuropathic pain by chronic constriction injury (CCI). Methods: 160 Swiss mice were randomly distributed into two groups: intrathecal pre-treatment group (PRE) aiming the effect

Julia Risso Parisi, Ana Laura Martins de Andrade, Josie Resende Torres Silva, Marcelo Lourenço Silva

Acta Neurobiologiae Experimentalis , ISSUE 4, 317–322

Review Paper

The role of cannabinoids and endocannabinoid system in the treatment of epilepsy

many biochemical and physiological processes. By affecting glutamate and gamma-aminobutyric acid (GABA) neurotransmission cannabinoids have the ability to affect seizure threshold. The best known cannabinoid is cannabidiol, which inhibits the occurrence of seizures without causing significant side effects in humans and animals. However, only a small number of double blind, randomized and placebo controlled studies have been published to date. Conclusions. The role of cannabinoids in the treatment

Monika Pędracka, Jacek Gawłowicz

Journal of Epileptology , ISSUE 2, 131–138


Alteration of oxidative stress markers and behavior of rats in a novel model of depression

(Mormède et al., 1990), and aberrant maternal care or deprivation of it (Baram et al., 2012). Yet, some of these paradigms involve pain, inflammation, and noxious elements of a physical nature. In our study we used a model of emotional stress caused by ultrasound (US) exposure, which, unlike other types of stress, does not involve direct physical manipulation of the animals (Morozova et al., 2016). The main stress factor in this model is the unpredictable alternation of ultrasonic frequencies from 20

Anna Gorlova, Dmitrii Pavlov, Eugene Zubkov, Yana Zorkina, Anatoly Inozemtsev, Anna Morozova, Vladimir Chekhonin

Acta Neurobiologiae Experimentalis , ISSUE 3, 232–238

Research paper

Afferent projections of the subthalamic nucleus in the rat: emphasis on bilateral and interhemispheric connections

-examine the STN with an emphasis on poorly- or un-documented connections. Furthermore, the bilateral and interhemispheric connections of the STN are evaluated. Fifteen male albino rats received injections of Fluoro-Gold retrograde and biotinylated dextran amine anterograde tracers into the STN. Following a 7–10 day survival period, the animals were processed according to the relevant protocol for each tracer. The present study demonstrates ipsilateral connections of the STN with cortical regions (i.e

Safiye Çavdar, Merve Özgür, Yusuf Özgür Çakmak, Yasemin Kuvvet, Sıla Kezban Kunt, Gökay Sağlam

Acta Neurobiologiae Experimentalis , ISSUE 3, 251–263



, polyhydroxyalkanoates and gellan) [62, 86] and also by the ability to degrade recalcitrant compounds (among others, atrazine, chlorobiphenyl, m-toluate, polychlorinated biphenyl, nitrobenzene, 1,4-dichlorobenzene, 1,2,4-trichlorobenzene, naphthalene) [7, 15, 17, 19, 35, 42, 63, 69, 97]. Moreover, it is one of the most ecologically significant groups of bacteria – members of that genus are even present in terrestrial and marine environments and also in association with animals and plants. Such a free spread of

Katarzyna Leja, Kamila Szudera-Kończal, Kamila Myszka, Katarzyna Czaczyk

Postępy Mikrobiologii - Advancements of Microbiology , ISSUE 2, 177–190


Is a fatty pancreas a banal lesion?

(especially adrenal cortex hormones), disease of the liver and visceral adiposis. As regards lipomatosis of that organ resulting mainly from dyslipidemia and hyperglycemia, the term “nonalcoholic fatty pancreas disease” was introduced. Experimental studies on animals and histological preparations of the pancreatic fragments show that the lipotoxicity of the collected adipocytes collected ion the organ release a cascade of proinflammatory phenomena, and even induces the processes of carcinogenesis

Andrzej Smereczyński, Katarzyna Kołaczyk

Journal of Ultrasonography , ISSUE 66, 273–280

Abstract Supplements

Special Abstract Supplement, PhD Electronic Poster Evening, School of Psychology, Social Work and Social Policy, University of South Australia

two zoo-based education approaches Sarah Mellish*a, Elissa Pearsona, Ben Sandersb, Carla Litchfielda. a. University of South Australia; b. Zoos Victoria. Background: Marine debris poses a significant threat to marine biodiversity. Given human action is responsible for much of the debris that ends up in the ocean, one way to reduce the amount of debris and rates of marine wildlife entanglement (MWE; i.e. marine animals that have ingested, become entangled by, or trapped in marine debris including

John Mingoia, MD S.R Jabin, Cassie Hilditch, Stephanie Newton Webb, Sarah Mellish

Eat, Sleep, Work , ISSUE 1, 84–90

Abstract Supplements

Special Abstract Supplement, Adelaide Sleep Retreat, 6th Annual Meeting, 2015

deserves to be approached as an equally legitimate and significant form of co-sleeping. An understanding of human-animal co-sleeping has significant implications for human sleep, human-animal relations, and animal welfare, as well as clinical applications to human sleep and sleep hygiene. We argue that by approaching co-sleeping broadly as a social practice involving human relations with other human and non-human animals, we can fulfil a call for a greater understanding of the diverse manifestations

Emily Duncanson, Binh Truong, Justyna Pollok, Scott Coussens, Charlotte Gupta, Zachariah Reuben Cross, Emily Watson, Yaroslava King, Bradley Smith, David Stevens

Eat, Sleep, Work , ISSUE 1, 91–102

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