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Mini Review

Secondary Metabolites of Actinomycetes and their Antibacterial, Antifungal and Antiviral Properties

, macrolactins A1 and B1, chaxamycin D as well as anthracimycin are regarded as the most effective compounds with antibacterial activity. In turn, the highest potency among selected antifungal compounds is exhibited by enduspeptide B, neomaclafungins A-I and kribelloside D, while ahmpatinin iBu, antimycin A1a, and pentapeptide 4862F are recognized as the strongest antiviral agents.

KATARZYNA JAKUBIEC-KRZESNIAK, ALEKSANDRA RAJNISZ-MATEUSIAK, ADAM GUSPIEL, JOANNA ZIEMSKA, JOLANTA SOLECKA

Polish Journal of Microbiology , ISSUE 3, 259–272

original-paper

Antibacterial Activity and Mode of Action of β-caryophyllene on Bacillus cereus

functional groups including alcohol, aldehyde, phenol, ketone, ether, and hydrocarbon groups (Guimarães et al. 2019). These terpenes and terpenoids are secondary metabolites, which are often used as a functional food, food additives, medicines, nutritional supplements, and in the manufacture of cosmetics because they exhibit antibacterial, antioxidant, and anti-inflammatory properties (Zengin and Baysal 2014). Although it has been reported that the antibacterial activity of EOs can be attributed to the

CHEW-LI MOO, SHUN-KAI YANG, MOHD-AZURAIDI OSMAN, MOHD HAFIS YUSWAN, JIUN-YAN LOH, WEI-MENG LIM, SWEE-HUA-ERIN LIM, KOK-SONG LAI

Polish Journal of Microbiology , ISSUE 1, 49–54

Article

ANTIBACTERIAL EFFECT OF NATURAL OILS – AN OPPORTUNITY TO SOLVE THE PROBLEM OF ANTIBIOTIC RESISTANCE ON THE EXAMPLE OF PSEUDOMONAS SPP.

ferable aminoglycoside-modifying enzymes, of 16S rRNA methylases, and mutational derepression of intrinsic multidrug efflux [98]. 4.2. Resistance to fluoroquinolones Fluoroquinolones have a broad range of antibacterial activity which is useful in the treatment of different diseases (e.g., urinary tract infections, gastrointestinal infections, respiratory tract infections, sexually transmitted diseases, bone and joint infections, and infections of the skin and soft tissue) [80]. The fluoroquinolones

Katarzyna Leja, Kamila Szudera-Kończal, Kamila Myszka, Katarzyna Czaczyk

Postępy Mikrobiologii - Advancements of Microbiology , ISSUE 2, 177–190

original-paper

Inhibition of Drug Resistance of Staphylococcus aureus by Efflux Pump Inhibitor and Autolysis Inducer to Strengthen the Antibacterial Activity of β-lactam Drugs

required in the development of the new strategies for antimicrobial drug combinations against MRSA. One novel strategy is to utilize helper compounds in combination with traditional antibiotics. Helper compounds are drugs approved for other therapeutic purposes that also possess antibacterial activity (Dickey et al. 2017). Thioridazine (TZ) is primarily an antipsychotic drug and also functions as an efflux pump inhibitor, which can be used as a helper compound (Klitgaard et al. 2008; Pule et al. 2016

WENJING LUAN, XIAOLEI LIU, XUEFEI WANG, YANAN AN, YANG WANG, CHAO WANG, KESHU SHEN, HONGYUE XU, SHULIN LI, MINGYUAN LIU, LU YU

Polish Journal of Microbiology , ISSUE 4, 477–491

Short Communication

Search of the Antimicrobial Potential of Benzimidazole Derivatives

Monika Janeczko, Zygmunt Kazimierczuk, Andrzej Orzeszko, Andrzej Niewiadomy, Ewa Król, Ryszard Szyszka, Maciej Masłyk

Polish Journal of Microbiology , ISSUE 3, 359–364

Original Paper

Production, Characterization and Valuable Applications of Exopolysaccharides from Marine Bacillus subtilis SH1

;saccharides in different medical applications. Results concluded that, EPS exhibited antibacterial activity against Aeromonas hydrophila, Pseudomonas aeruginosa and Streptococcus faecalis and the highest antibacterial activity (7.8, 9 and 10.4 AU/ml) was against S. faecalis at 50, 100 and 200 mg/ml respectively. The EPS exhibited various degree of antitumor effect toward the tested cell lines (MCF-7, HCT-116 and HepG2). In addition, EPS exhibited antiviral activity at 500 μg/ml. The antioxidant

Sahar W.M. Hassan, Hassan A.H. Ibrahim

Polish Journal of Microbiology , ISSUE 4, 449–461

Short Communication

Inhibition of Multidrug-Resistant Gram-Positive and Gram-Negative Bacteria by a Photoactivated Porphyrin

The authors studied the in vitro antibacterial activity of the photo-activated porphyrin meso-tri(N-methyl-pyridyl), mono(N-tetradecyl-pyridyl)porphine (C14) against four multidrug-resistant bacteria: Staphylococcus aureus, Enterococcus faecalis (Gram-positive), Escherichia coli, Pseudomonas aeruginosa (Gram-negative). Using 10 μg/ml of porphyrin and 60 sec irradiation we observed the remarkable suscep­tibility of S. aureus and E. faecalis to treatment while, under the same conditions, E

Moreno Bondi, Anna Mazzini, Simona De Niederhäusern, Ramona Iseppi, Patrizia Messi

Polish Journal of Microbiology , ISSUE 4, 533–536

Short Communication

The Effect of Local Platelet Rich Plasma Therapy on the Composition of Bacterial Flora in Chronic Venous Leg Ulcer

Witold Woźniak, Monika Tarnas, Tomasz Miłek, R. Krzysztof Mlosek, Piotr Ciostek

Polish Journal of Microbiology , ISSUE 3, 353–357

Original Paper

Characterisation of Antimicrobial Properties of Extracts of Selected Medicinal Plants

The scope of the experiments included analysis of the antimicrobial activity of ethanolic, methanolic and aqueous extracts against bacterial and fungal cultures and determination of the minimum inhibitory concentration of plant extracts tested microbial growth. Analysis of the antifungal and antibacterial activity was carried out by the disc diffusion method using paper discs. In the experiment 11 species of microorganisms – 8 bacterial and 3 fungal strains were used. The highest

Monika Cioch, Paweł Satora, Magdalena Skotniczy, Dorota Semik-Szczurak, Tomasz Tarko

Polish Journal of Microbiology , ISSUE 4, 463–472

Original Research

Optimization of Mixed Solid-state Fermentation of Soybean Meal by Lactobacillus Species and Clostridium butyricum

50% after two days of fermentation. Furthermore, the exogenous proteases used in combination with probiotics supplementation were further able to enhance the viable count of bacteria, degradation of soybean protein and lactic acid level in the fermented soybean meal. In addition, the pH value and sugar content in fermented soybean meal were considerably reduced in the presence of both proteases and probiotics. Furthermore, the fermented soybean meal also showed antibacterial activity against

LI-WEN SU, YEONG-HSIANG CHENG, FELIX SHIH-HSIANG HSIAO, JIN-CHENG HAN, YU-HSIANG YU

Polish Journal of Microbiology , ISSUE 3, 297–305

original-paper

Bioactive Compounds of Pseudoalteromonas sp. IBRL PD4.8 Inhibit Growth of Fouling Bacteria and Attenuate Biofilms of Vibrio alginolyticus FB3

summarizes the characteristics of the identified compounds. Furthermore, 12 out of the remaining 17 unidentified compounds were found to be nitrogen-containing compounds. The compound 4,7,10,13-hexadecatetraenoic acid (C16H24O2) as a type of polyunsaturated fatty acids was anticipated to be the compound responsible for the antibacterial activity of the sub-fraction F3a. Table III Characteristics of compounds from LC-MS analysis of sub-fraction F3a. No. RT (min) Compound Mass m/z [M-H

NOR AFIFAH SUPARDY, DARAH IBRAHIM, SHARIFAH RADZIAH MAT NOR, WAN NORHANA MD NOORDIN

Polish Journal of Microbiology , ISSUE 1, 21–33

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