, macrolactins A1 and B1, chaxamycin D as well as anthracimycin are regarded as the most effective compounds with antibacterial activity. In turn, the highest potency among selected antifungal compounds is exhibited by enduspeptide B, neomaclafungins A-I and kribelloside D, while ahmpatinin iBu, antimycin A1a, and pentapeptide 4862F are recognized as the strongest antiviral agents.
Polish Journal of Microbiology , ISSUE 3, 259–272
functional groups including alcohol, aldehyde, phenol, ketone, ether, and hydrocarbon groups (Guimarães et al. 2019). These terpenes and terpenoids are secondary metabolites, which are often used as a functional food, food additives, medicines, nutritional supplements, and in the manufacture of cosmetics because they exhibit antibacterial, antioxidant, and anti-inflammatory properties (Zengin and Baysal 2014). Although it has been reported that the antibacterial activity of EOs can be attributed to the
MOHD HAFIS YUSWAN,
Polish Journal of Microbiology , ISSUE 1, 49–54
ferable aminoglycoside-modifying enzymes, of 16S rRNA methylases, and mutational derepression of intrinsic multidrug efflux .
Resistance to fluoroquinolones
Fluoroquinolones have a broad range of antibacterial activity which is useful in the treatment of different diseases (e.g., urinary tract infections, gastrointestinal infections, respiratory tract infections, sexually transmitted diseases, bone and joint infections, and infections of the skin and soft tissue) . The fluoroquinolones
Postępy Mikrobiologii - Advancements of Microbiology , ISSUE 2, 177–190
required in the development of the new strategies for antimicrobial drug combinations against MRSA.
One novel strategy is to utilize helper compounds in combination with traditional antibiotics. Helper compounds are drugs approved for other therapeutic purposes that also possess antibacterial activity (Dickey et al. 2017). Thioridazine (TZ) is primarily an antipsychotic drug and also functions as an efflux pump inhibitor, which can be used as a helper compound (Klitgaard et al. 2008; Pule et al. 2016
Polish Journal of Microbiology , ISSUE 4, 477–491
Polish Journal of Microbiology , ISSUE 3, 359–364
;saccharides in different medical applications. Results concluded that, EPS exhibited antibacterial activity against Aeromonas hydrophila, Pseudomonas aeruginosa and Streptococcus faecalis and the highest antibacterial activity (7.8, 9 and 10.4 AU/ml) was against S. faecalis at 50, 100 and 200 mg/ml respectively. The EPS exhibited various degree of antitumor effect toward the tested cell lines (MCF-7, HCT-116 and HepG2). In addition, EPS exhibited antiviral activity at 500 μg/ml. The antioxidant
Sahar W.M. Hassan,
Hassan A.H. Ibrahim
Polish Journal of Microbiology , ISSUE 4, 449–461
The authors studied the in vitro antibacterial activity of the photo-activated porphyrin meso-tri(N-methyl-pyridyl), mono(N-tetradecyl-pyridyl)porphine (C14) against four multidrug-resistant bacteria: Staphylococcus aureus, Enterococcus faecalis (Gram-positive), Escherichia coli, Pseudomonas aeruginosa (Gram-negative). Using 10 μg/ml of porphyrin and 60 sec irradiation we observed the remarkable susceptibility of S. aureus and E. faecalis to treatment while, under the same conditions, E
Simona De Niederhäusern,
Polish Journal of Microbiology , ISSUE 4, 533–536
R. Krzysztof Mlosek,
Polish Journal of Microbiology , ISSUE 3, 353–357
The scope of the experiments included analysis of the antimicrobial activity of ethanolic, methanolic and aqueous extracts against bacterial and fungal cultures and determination of the minimum inhibitory concentration of plant extracts tested microbial growth. Analysis of the antifungal and antibacterial activity was carried out by the disc diffusion method using paper discs. In the experiment 11 species of microorganisms – 8 bacterial and 3 fungal strains were used. The highest
Polish Journal of Microbiology , ISSUE 4, 463–472
50% after two days of fermentation. Furthermore, the exogenous proteases used in combination with probiotics supplementation were further able to enhance the viable count of bacteria, degradation of soybean protein and lactic acid level in the fermented soybean meal. In addition, the pH value and sugar content in fermented soybean meal were considerably reduced in the presence of both proteases and probiotics. Furthermore, the fermented soybean meal also showed antibacterial activity against
FELIX SHIH-HSIANG HSIAO,
Polish Journal of Microbiology , ISSUE 3, 297–305
summarizes the characteristics of the identified compounds. Furthermore, 12 out of the remaining 17 unidentified compounds were found to be nitrogen-containing compounds. The compound 4,7,10,13-hexadecatetraenoic acid (C16H24O2) as a type of polyunsaturated fatty acids was anticipated to be the compound responsible for the antibacterial activity of the sub-fraction F3a.
Characteristics of compounds from LC-MS analysis of sub-fraction F3a.
NOR AFIFAH SUPARDY,
SHARIFAH RADZIAH MAT NOR,
WAN NORHANA MD NOORDIN
Polish Journal of Microbiology , ISSUE 1, 21–33