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Chemical Composition of Aspergillus creber Extract and Evaluation of its Antimicrobial and Antioxidant Activities

. creber was also reported as among the lower producers of STC (Jurjevic et al. 2013). Therefore, the lack of knowledge of this species recently assigned to section Versicolores has attracted our attention to more explore and study this species. In our research A. creber was assayed for its secondary metabolites diversity using UHPLC-MS/MS technique. Then, the antimicrobial activity of A. creber against some human pathogens and its ability to scavenge different free radicals, and to produce antioxidant


Polish Journal of Microbiology , ISSUE 3, 309–316


Lactobacillus fermentum JX306 Restrain D-galactose-induced Oxidative Stress of Mice through its Antioxidant Activity

Introduction Oxidative stress refers to an imbalance, which is caused by high levels of reactive oxygen species (ROS) and low levels of antioxidant activity (Preiser 2012). The excessive ROS can damage enzymes, fatty acids, proteins, nucleic acids, and other physiological substances of cells, which leads to structure and function disorders (Dizdaroglu et al. 1992; Wu et al. 2014). The oxidative stress can cause various diseases, including amyotrophic lateral sclerosis, asthma, allergies, and


Polish Journal of Microbiology , ISSUE 2, 205–215

Research paper

The effects of edaravone in ketamine-induced model of mania in rats

Bipolar disorder is a chronic disease characterized by recurring episodes of mania and depression that can lead to disability. This study investigates the protective effects of edaravone (3-methyl-1-phenyl-2-pyrazolin-5-one), a drug with well-known antioxidant properties, in a model of mania induced by ketamine in rats. Locomotor activity was assessed in the open-field test. Superoxide dismutase (SOD), catalase (CAT) and thiobarbituric acid reactive substances (TBARS) levels were measured in

Filiz Civil Arslan, Ahmet Tiryaki, Mehmet Yıldırım, Evrim Özkorumak, Ahmet Alver, İlkay Keleş Altun, İmran İnce, Öznur Gedikli

Acta Neurobiologiae Experimentalis , ISSUE 3, 192–198

Research paper

Long-term consumption of fermented rooibos herbal tea offers neuroprotection against ischemic brain injury in rats

adult male Wistar rats. FRHT was administered to the animals ad libitum for 7 weeks prior to the induction of ischemic injury via a 20-minute bilateral occlusion of the common carotid arteries (BCCAO) followed by reperfusion for 24, 96 and 168 hours respectively. Neurobehavioural deficits, brain oedema, blood-brain barrier (BBB) damage, apoptosis, lipid peroxidation and total antioxidant capacity were subsequently evaluated using standard methods. Our results showed that long-term consumption of

Olusiji Akinrinmade, Sylvester Omoruyi, Daneel Dietrich, Okobi Ekpo

Acta Neurobiologiae Experimentalis , ISSUE 1, 94–105

Research Article


Human population in the XXI century is struggling with the increasing incidence of such diseases as obesity, diabetes, cancers, food allergies and many others. Recent studies have shown that oxidative stress caused by reactive oxygen species and free radicals, may underlie the occurrence of many diseases. Probiotics are known for their beneficial effects on health and are established as dietary adjuncts. Researchers are trying to find potential probiotic strains which can exhibit antioxidant

Nina Trojan, Paweł Satora

Postępy Mikrobiologii - Advancements of Microbiology , ISSUE 1, 18–27


C60 fullerenes increase the intensity of rotational movements in non-anesthetized hemiparkinsonic rats

provided by the antioxidant system (Banerjee et al., 2003). Although the mechanisms of skeletal muscle fatigue have been described in detail (Boyas and Guével, 2011), the problem of preventing or correcting muscle fatigue remains unresolved. In studies of muscle fatigue, endogenous antioxidants, such as N-acetylcysteine and β-alanine, are widely used and speed up the muscle recovery process after fatigue (Reid et al., 1994; Harris and Sale, 2012). Recently, it was shown that bioactive soluble carbon

Andriy V. Maznychenko, Olena P. Mankivska, Inna V. Sokolowska (Vereshchaka), Bohdan S. Kopyak, Tomasz Tomiak, Nataliya V. Bulgakova, Olga O. Gonchar, Yuriy I. Prylutskyy, Uwe Ritter, Iryna V. Mishchenko, Alexander I. Kostyukov

Acta Neurobiologiae Experimentalis , ISSUE 1, 32–37

Research paper

Nicorandil attenuates neuronal mitochondrial dysfunction and oxidative stress associated with murine model of vascular calcification

were studied. Nicorandil (7.5 mg/kg b.wt.) was given either concomitantly or after the induction of calcification. The brain tissues were evaluated for antioxidant capacity, mitochondrial enzymes and oxidative phosphorylation efficiency along with the progression of calcification. The results suggested that renal failure, elevated the calcium, phosphorus product in the brain. The brain cytoplasm and mitochondrial fractions showed an elevated TBARS and a corresponding decline in the antioxidant

Sriram Ravindran, Krithika Swaminathan, Abhinaya Ramesh, Gino A. Kurian

Acta Neurobiologiae Experimentalis , ISSUE 1, 57–67

Research paper

Effects of Cornus mas L. and Morus rubra L. extracts on penicillin-induced epileptiform activity: an electrophysiological and biochemical study#

Filiz Tubaş, Sedat Per, Abdulkadir Taşdemir, Ayşe Kaçar Bayram, Mehmet Yıldırım, Aydın Uzun, Recep Saraymen, Hakan Gümüş, Ferhan Elmalı, Hüseyin Per

Acta Neurobiologiae Experimentalis , ISSUE 1, 45–56

Original Paper

Complex Biochemical Analysis of Fruiting Bodies from Newly Isolated Polish Flammulina velutipes Strains

for antioxidant and bacteriostatic abilities. We have proved that Polish F. velutipes fruiting bodies may be a rich source of antioxidants and that they are capable of inhibiting Staphylococcus aureus growth.

Monika Osińska-Jaroszuk, Magdalena Jaszek, Justyna Sulej, Dawid Stefaniuk, Monika Urbaniak, Marek Siwulski, Grzegorz Janusz

Polish Journal of Microbiology , ISSUE 3, 295–305


The inhibitory effects of bile acids on catalytic and non-catalytic functions of acetylcholinesterase as a therapeutic target in Alzheimer’s disease

Leila Sadeghi, Reza Yekta, Gholamreza Dehghan

Acta Neurobiologiae Experimentalis , ISSUE 2, 108–116

Research paper

Effects of epidural compression on stellate neurons and thalamocortical afferent fibers in the rat primary somatosensory cortex

observed in some myelinated TCA fibers. In addition, expressions of oxidative markers 3-nitrotyrosine and 4-hydroxynonenal were elevated in barrel field post-lesion. Treatment of antioxidant ascorbic acid or apocynin was able to reverse the increase of oxidative stress and the decline of TCA fiber density, rather than the shrinkage of dendrites and the stripping of dendritic spines of stellate neurons post-lesion. Together, these results indicate that sustained epidural compression of primary

Tzu-Yin Yeh, Guo-Fang Tseng, Chi-Yu Tseng, Yung-Hsin Huang, Pei-Hsin Liu

Acta Neurobiologiae Experimentalis , ISSUE 1, 1–17

Research Article


anti-inflammatory agent, and also anti-inflammatory, neuroprotective, antioxidant and antiapoptotic properties of minocycline. Futhermore, the basics of demeclocycline application in the treatment of inappropriate antidiuretic hormone hypesecretion syndrome and rifaximin use as an anti-inflammatory and eubiotic agent are presented. Neuroprotective action of ceftriaxone and anti-inflammatory and immunostimulatory action of fusafungine were also described.

Maciej Danielewski, Dorota Ksiądzyna, Adam Szeląg

Postępy Mikrobiologii - Advancements of Microbiology , ISSUE 4, 301–312

Original Paper

Production, Characterization and Valuable Applications of Exopolysaccharides from Marine Bacillus subtilis SH1

;saccharides in different medical applications. Results concluded that, EPS exhibited antibacterial activity against Aeromonas hydrophila, Pseudomonas aeruginosa and Streptococcus faecalis and the highest antibacterial activity (7.8, 9 and 10.4 AU/ml) was against S. faecalis at 50, 100 and 200 mg/ml respectively. The EPS exhibited various degree of antitumor effect toward the tested cell lines (MCF-7, HCT-116 and HepG2). In addition, EPS exhibited antiviral activity at 500 μg/ml. The antioxidant

Sahar W.M. Hassan, Hassan A.H. Ibrahim

Polish Journal of Microbiology , ISSUE 4, 449–461

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