research-article
Introduction
Anxiety disorders are prevalent among children and may have long-term negative impact on individuals’ personal, social, and academic functioning (1). Several factors may influence the development and maintenance of anxiety in children, including genetic, physiological, temperamental, parental, and family-context related risks (2-4). Increased knowledge about factors that influence the level of anxiety symptoms in children is needed to improve clinical practice, as well as to
Krister Westlye Fjermestad,
Christina Lium,
Einar R. Heiervang,
Odd E. Havik,
Bente Storm Mowatt Haugland,
Ingvar Bjelland,
Gro Janne Henningsen Wergeland
Scandinavian Journal of Child and Adolescent Psychiatry and Psychology , 18–24
Research paper
Objective Given that the literature data indicates that ascorbic acid may have an anxiolytic effect, we hypothesized that a single oral administration of ascorbic acid could acutely affect emotional states. Methods The effects of acid ascorbic supplementation on anxiety and other emotional states were evaluated by the State-Trait Anxiety Inventory (STAI), and Visual Analogue Mood Scale (VAMS). Immediately before, and 2 hours after receiving a single ascorbic acid dose (1000 mg) or placebo, 142
Bettina Moritz,
Marcelo Liborio Schwarzbold,
Ricardo Guarnieri,
Alexandre Paim Diaz,
Ana Lúcia S. Rodrigues,
Alcir Luiz Dafre
Acta Neurobiologiae Experimentalis , ISSUE 4, 362–372
Review Paper
Introduction. People with epilepsy (PWE) have a higher risk of developing depression and anxiety than people without epilepsy. However, understanding and management of that issue remain under-recognized. Aim. To emphesize: a) the relationship between depression, anxiety, and epilepsy, and b) to suggest practical strategies for their identification by clinicians. Methods. The current literatures was reviewed investigating the impact of depression and anxiety in PWE and those examining the
Sung-Pa Park
Journal of Epileptology , ISSUE 1, 57–62
Research Article
Parental rearing practices such as over-involvement are associated with childhood anxiety; however, little is known about the contribution of parental perceptions to child anxiety. This study explores the relationship between maternal and paternal perceptions of parenting and childhood anxiety. The perceived rearing behaviors and parental sense of competence (i.e., satisfaction and efficacy) of the parents of anxious children (n = 59) were compared with those of a non-clinical control sample (n
Barbara H. Esbjørn,
Ida D. Caspersen,
Mikael J. Sømhovd,
Sonja Breinholst,
Marie Louise Reinholdt-Dunne
Scandinavian Journal of Child and Adolescent Psychiatry and Psychology , ISSUE 3, 115–123
Research Article
Reports of anxiety disorder characteristics among youth in clinical settings typically include descriptions of patients who have been specifically referred for anxiety treatment. At odds with a large body of evidence which demonstrates these disorders to be most common among young people, prevalence studies in samples referred to general psychiatry for multiple causes are scarce and report highly discrepant estimates.For this study and regardless of their presenting symptoms, 125 adolescents
Susanne Olofsdotter,
Sofia Vadlin,
Karin Sonnby,
Tomas Furmark,
Kent W. Nilsson
Scandinavian Journal of Child and Adolescent Psychiatry and Psychology , ISSUE 2, 55–64
Research paper
Anxiety disorders are a social problem due to their prevalence and consequences. It is crucial to explore the influence of anxiety on cognitive processes. In this study we recorded EEG activity from 73 subjects (35 patients, 38 controls, matched for age and education)during performance of the Continuous Attention Task. We used low resolution electromagnetic tomography (LORETA) for evaluation of mechanisms of impaired cognitive performance in anxiety disorders. Analysis showed that
Bartłomiej Gmaj,
Piotr Januszko,
Jan Kamiński,
Ewa Drozdowicz,
Maciej Kopera,
Dorota Wołyńczyk-Gmaj,
Waldemar Szelenberger,
Marcin Wojnar
Acta Neurobiologiae Experimentalis , ISSUE 1, 75–85
research-article
Introduction
Anxiety disorders are some of the most common psychiatric disorders among children and adolescents (hereafter referred to as youths) (1,2). In an epidemiological meta-analysis, the prevalence for any anxiety disorder was found to be 12.3% among children (age 6-12 years old) and 11.0% for adolescents (age 13-18 years old) (1). In Denmark, the yearly number of youths diagnosed with depression or an anxiety disorder has tripled from 2006 to 2016 (3). Although many anxiety disorders
Daniel Bach Johnsen,
Kristian Arendt,
Mikael Thastum
Scandinavian Journal of Child and Adolescent Psychiatry and Psychology , 68–80
research-article
INTRODUCTION
Alzheimer’s disease (AD) is a progressive neurodegenerative disease which is clinically characterized by dementia and neurobehavioral impairments mainly on memory functions (Kar et al., 2004). Additionally, significant behavioral changes such as progressive memory loss, anxiety, agitation and irritability are observed.
AD is categorized into two types: late-onset sporadic AD and early-onset familial AD (Dorszewska et al., 2016). The first one represents 95% of all the cases
Gabrielle Pfutzenreuter,
Kenny Nieradka,
Márcia Regina Pincerati,
Ilton Santos da Silva
Acta Neurobiologiae Experimentalis , ISSUE 2, 160–169
Research paper
Eltoprazine, a drug that had previously been developed for aggression, has recently been investigated for L-DOPA-induced dyskinesia in animal models of Parkinson´s disease (PD) and in dyskinetic PD patients. Much less is known about effects of eltoprazine in other therapeutic indications. Indeed, the pharmacological profile of eltoprazine might suggest its effects on anxiety and food intake, but also adverse effect potential, which is the focus of the present study.
Given for 2 weeks either as
Andreas Gravius,
Andrzej Dekundy,
Anita Vanaga,
Lutz Franke,
Wojciech Danysz
Acta Neurobiologiae Experimentalis , ISSUE 1, 77–85
research-article
.
Diabetes has many complications including cardiomyopathy, retinopathy, neuropathy, nephropathy, as well as affecting the mental status of the patients. Various psychological comorbidities, such as depression and anxiety, are associated with diabetes (Ducat et al., 2014) and the prognosis is worse in patients with poor glycemic control (Lustman et al., 2000). In addition to clinical studies, behavioral alterations were demonstrated in experimental models in different species. Streptozotocin (STZ) is the
Hasan Caliskan,
Firat Akat,
Goktug Omercioglu,
Gulbahar Bastug,
Hakan Ficicilar,
Metin Bastug
Acta Neurobiologiae Experimentalis , 1–11
Research paper
Marble burying is considered an, albeit controversial, animal model of the compulsive like behaviors of obsessive-compulsive disorder (OCD). Hallmark features of OCD patients are similarities and, more prominent, differences from anxiety disorders, e.g., the absence of sex differences and resistance to spontaneous remission. We report an experiment on marble burying by male and female C57/BL6/N mice. Animals were administered either the classic anxiolytic drug, diazepam, that targets the GABA
George T. Taylor,
Sandra Lerch,
Sabine Chourbaji
Acta Neurobiologiae Experimentalis , ISSUE 3, 254–260
Research paper
We have previously observed impairing effects of social defeat stress (CSDS) on inhibitory avoidance (IA) in mice. Given the similarity between changes produced by social stress in animals and symptoms of certain human psychopathologies such as depression and anxiety, the effects of the antidepressant clomipramine on IA impairment produced by CSDS were evaluated in the present study. Male CD1 mice were randomly assigned to the groups: non-stressed+saline, non-stressed+clomipramine, stressed
Aranzazu Duque,
Concepción Vinader-Caerols,
Santiago Monleón
Acta Neurobiologiae Experimentalis , ISSUE 3, 225–233
Research paper
established (i.e., treatment). A battery of behavioral and cognitive tests were performed, including open-field, elevated plus maze, Porsolt’s forced swim, and Morris’ water maze, to evaluate anxietyand depression-like behaviors, and learning and memory. Results showed that chia supplementation was ineffective against Alzheimer’s-related anxiety, whereas depression-like behaviors were attenuated with both pretreatment and treatment. There was no improvement in learning and memory with chia treatment
Yasemin Bilgic,
Enver Ahmet Demir,
Nilufer Bilgic,
Hatice Dogan,
Okan Tutuk,
Cemil Tumer
Acta Neurobiologiae Experimentalis , ISSUE 4, 322–331
research-article
-Gresa et al., 2014). Marlau™ cages (MCs) were designed to standardize the stimulation of cognitive functions by exposing rodents to problem-solving opportunities during enrichment procedures that involve mazes and running wheels (Fares et al., 2012; Kentropp et al., 2018). In a prior study, it was reported that male Sprague-Dawley rats allocated to MCs displayed decreased anxiety-like behaviour in the elevated plus maze (EPM), enhanced performance in the Morris water maze, and stronger emotional
Raisa Rabadán,
Marta Ramos-Campos,
Rosa Redolat,
Patricia Mesa-Gresa
Acta Neurobiologiae Experimentalis , ISSUE 4, 374–385
short-report
1.
Introduction
Each year in Australia, approximately 12,000 Australian Defence Force (ADF) personnel are deployed in military service (1). Mental health problems including Post-traumatic Stress Disorder (PTSD, i.e., a set of symptoms such as traumatic flashbacks, avoidance, feeling emotionally numb, negative thoughts and mood, and agitation) (1,2), anxiety (3) and depression (1) may develop in some personnel as a result of exposure to traumatic experiences during such service. In addition
S Cloete,
L Chantler
Eat, Sleep, Work , 39–53
Research Article
, oppositional defiant disorder, conduct disorder, separation anxiety disorder, generalized anxiety disorder, and major depressive disorder.Results:The criterion validity for BCFPI versus LEAD diagnoses was fair for oppositional defiant disorder (area under curve, 0.73), generalized anxiety disorder (0.73) and major depressive disorder (0.78), good for attention-deficit hyperactivity disorder (0.81) and conduct disorder (0.83), and excellent for separation anxiety disorder (0.90). The screening properties of
Markus Andersson,
Martin Bäckström,
Tord Ivarsson,
Maria Råstam,
Håkan Jarbin
Scandinavian Journal of Child and Adolescent Psychiatry and Psychology , ISSUE 2, 83–90
Research Article
problems, with particular focus on symptoms of anxiety, depression, and ADHD. We also examined the potential mediating role of peer problems in the relationship between such symptoms and QoL.Methods:The sample consisted of 603 adolescents (ages 13-18) referred to clinical assessment. Psychiatric diagnoses according to the criteria of the International Statistical Classification of Diseases and Related Health Problems, 10th revision, were collected from participants’ clinical charts. Symptoms of
Ingunn Ranøyen,
Eva Gulliksrud,
Marit S. Indredavik,
Frode Stenseng
Scandinavian Journal of Child and Adolescent Psychiatry and Psychology , ISSUE 4, 183–192
Research Article
This study investigated and compared the prevalence of psychological difficulties among Danish, immigrant, and refugee children.We enrolled 332 children between the ages of 8 and 18 years (148 Danish children, 81 immigrant children, and 67 children with refugee backgrounds), all from low-income areas of residence. The Health Behaviour in School-aged Children Symptoms Checklist, the Strengths and Difficulties Questionnaire, and the Revised Children’s Anxiety and Depression Scale were applied.We
Ingrid Leth,
Janni Niclasen,
Else Ryding,
Yasmine Baroud,
Barbara H. Esbjørn
Scandinavian Journal of Child and Adolescent Psychiatry and Psychology , ISSUE 1, 29–37
research-paper
INTRODUCTION
Depression is one of the most common and most disabling mental disorders characterised by a major burden on both the patients and society as a whole. The most common symptoms of depression include low mood, low self-esteem, sleeping disorders and anxieties, which together frequently lead to suicides. It should be noted that the incidence of both (depression and anxiety disorders) have been on the rise, which may be related to longer lifespans, unemployment, migrations
Piotr Ratajczak,
Krzysztof Kus,
Tomasz Zaprutko,
Mikołaj Szczepański,
Sandra Rusowicz,
Elżbieta Nowakowska
Acta Neurobiologiae Experimentalis , ISSUE 1, 13–24
Research paper
Prolonged or repeated seizures have been shown to cause spontaneous recurrent seizures, increased anxiety-related behavior, locomotor hyperactivity, impaired functions of learning and memory, and neuronal damage in the hippocampus and other brain regions in animals. Mice and rats treated with antimuscarinic drugs after fasting for two days or less develop convulsions after being allowed to eat ad libitum. To address whether such behavioral and neuroanatomic changes occur following these
Nurhan Enginar,
Asiye Nurten,
Aslı Zengin Türkmen,
Gül İpek Gündoğan,
Zeynep Güneş Özünal
Acta Neurobiologiae Experimentalis , ISSUE 4, 373–381
research-paper
light box (p<0.05) compared to control animals. Cadmium administration induced anxiogenic behavior as shown by significantly decreased latency (P<0.01) and time spent in the light box (P<0.01) when compared with control animals. The Alm+Cad group showed significantly increased latency (P<0.01) and time spent in light box (P<0.01) compared to cadmium-treated rats, indicating attenuation of cadmium-induced anxiety by almond supplementation.
Fig. 3.
Anxiety-like behavior was assessed by using a light
Zehra Batool,
Faiza Agha,
Saiqa Tabassum,
Tuba Sharf1 Batool,
Rafat Ali Siddiqui,
Saida Haider
Acta Neurobiologiae Experimentalis , ISSUE 2, 169–183
Research Article
” feelings of distress without forcing any specific person into a supportive discussion. In addition, SNSs were described as lower-stress means of communication that allowed responses to be carefully formulated; this led to participants sharing information that they would not have shared during face-to-face interactions. However, participants also described anxiety surrounding the pressure to be active on SNSs, and they found it stressful to be exposed to pictures and posts involving former romantic
Gerrit Ian van Schalkwyk,
Katherine Klingensmith,
Paige McLaughlin,
Zheala Qayyum
Scandinavian Journal of Child and Adolescent Psychiatry and Psychology , ISSUE 2, 108–114
Research Article
In recent years, the incoming information about the emergence of new superbacteria and superviruses has been causing growing anxiety. However, also fungi are with increasing frequency reported as the sources of intercontinental microbiological hazards. According to the latest reports, quickly spreading, multidrug-resistant and difficult to identify yeast Candida auris may soon become the center of attention for clinicians, laboratory diagnosticians and the groups of advisers on the hospital
Dominika Grondalska,
Wioletta Kmieciak
Postępy Mikrobiologii - Advancements of Microbiology , ISSUE 3, 282–288
Research Article
, anxiety and worry and negatively with self-esteem. Girls reported higher stress levels than boys in eight of the nine scales. Stressors related to peer pressure predicted reported levels of anxiety and worry one year later, whereas stressors related to romantic relationships predicted depressive symptoms.Conclusions:Overall this study suggests that the ASQ-S could be a valid measure of adolescent stressor experience and psychometrically equivalent to the full ASQ-2.
Malin K. Anniko,
Katja Boersma,
Nikil Ph. L. van Wijk,
Don Byrne,
Maria Tillfors
Scandinavian Journal of Child and Adolescent Psychiatry and Psychology , ISSUE 1, 4–15
Article
Visual pollution in the urban facade is one of the causes of distress and anxiety in today’s cities. The purpose of this research is to achieve disruption and tranquility causing factors in new and old facades in Jolfa district of Isfahan and finally preparing design tips of a safe, relaxing and without visual pollution facade. Therefore, archival and field work documentation has been analyzed and according to the statistical with SPSS 20 software investigated correlation between variables. The
Sina RAZZAGHI-ASL,
Afrooz Rahimi ARIAEI,
Sama Barati GHAHFAROKHICI
Architecture, Civil Engineering, Environment , ISSUE 3, 57–70
Case report
(RBCs) in the apheresis unit as part of her regular treatment. When the patient started receiving the implicated unit, she reported back pain, chest pain, and a feeling of anxiety, suggestive of an acute transfusion reaction. The transfusion was ceased and an investigation of an adverse event was commenced. This case illustrates that the presence of antibodies to low-prevalence antigens remains a significant issue for transfusion-dependent individuals. To prevent other transfusion reactions by anti
Arthur J. Joyce,
Kelli M Quantock,
Ray Banh,
Yew-Wah Liew
Immunohematology , ISSUE 1, 6–8
Review
Mood disorders are relatively common serious human diseases for which there is often no ideal pharmacotherapy. Basic characteristic of these diseases is affective disorder shifting the mood of the patient to depression (together with anxiety or not) or towards to euphoria. Available drugs are usually divided into two groups – mood stabilizers, which are used primarily to treat bipolar disorder,and antidepressants for the treatment of unipolar depression. Lithium is still recommended as the
Miroslava Vosahlikova,
Petr Svoboda
Acta Neurobiologiae Experimentalis , ISSUE 1, 1–19
review-article
seizures, multiple drug therapy and frequent changes of pharmacotherapy, excessive use of alcohol, frontal lobe epilepsy, mental dysfunctions, co-occurring anxiety and depression disorders, and using lamotrigine (women in particular) (Tomson, 2000; Tomson et al., 2005; Hesdorffer, Tomson, 2013; Tomson et al., 2013; Holst et al., 2013; Granbichler et al., 2015; Tomson et al., 2016). According to Walczak (2003), the results of most studies have not revealed a relationship between any AED and SUDEP. There
Barbara Błaszczyk,
Aleksandra Walczak,
Natalia Ścirka,
Agnieszka Konarzewska,
Barbara Miziak,
Stanisław J. Czuczwar
Journal of Epileptology , 15–26
research-article
INTRODUCTION
Valproic acid (2-propylpentanoic acid) is a branched-short-chain fatty acid derived from valeric acid which is extracted from Valeriana officinalis (Fan et al., 2016; Tomson et al., 2016). Valproic acid is commonly used for the treatment of epilepsy, psychiatric disorders such as bipolar disorder and anxiety and prophylaxis of a migraine (Ghodke-Puranik et al., 2013; Terbach and Williams, 2009; Tseng et al., 2017).
Valproic acid is well absorbed and has a very high ability to bind
Santoso Jaeri,
Wardah Rahmatul Islamiyah
Journal of Epileptology , ISSUE 1-2, 49–54
research-article
data exist on the role of single signs or symptoms in confirming or excluding PNES, as sensitivity and specificity are generally suboptimal. Prolactin and creatinkinase are reliable serum biomarkers, as normal values within a few hours after an episode may help confirm the diagnosis of PNES. However, the sole normality of these levels does not exclude the diagnosis of ES. Many psychiatric conditions are common in people with PNES, including depression, anxiety, post-traumatic stress disorders
Massimiliano Beghi,
Cesare Maria Cornaggia,
Ettore Beghi
Journal of Epileptology , 27–32
Research Article
One-session treatment (OST) is a short-term massed exposure therapy for the treatment of specific phobias in children and adults. Systematic reviews have demonstrated the effectiveness of the treatment for children and adolescents across countries and age groups.A single-group open trial design was used to examine the feasibility and preliminary efficacy of OST for youths with specific phobias in a Danish context.At the Anxiety Clinic of Aarhus University, 10 youths between the ages of 7 and 17
Mette Djernes Nielsen,
Christina Linddahl Andreasen,
Mikael Thastum
Scandinavian Journal of Child and Adolescent Psychiatry and Psychology , ISSUE 2, 65–76
Case report
violence exposure.Methods:Detailed psychiatric and neuropsychological assessment was performed initially, followed by a PET study. The PET imaging was carried out in the resting-state and in the dissociative-state.Results:The adolescent was suffering from multiple episodes of unconsciousness, all found to be psychogenic; thus, PNES was diagnosed. However, at the psychopathology symptom level, the adolescent had heightened impulsivity, hyperactivity, hyperarousal, anxiety, somatic, and dissociative
Dejan Stevanovic,
Leposava Brajkovic,
Madhur Kumar Srivastava,
Ivan Krgovic,
Jasna Jancic
Scandinavian Journal of Child and Adolescent Psychiatry and Psychology , ISSUE 2, 98–106
book-review
and research on age-appropriate adaptations and validation of disorders for infants, toddlers and preschool-aged children are increasing (14, 15). Emerging evidence (12, 16, 17) has shown that comorbid disorders such as oppositional defiant disorder (ODD), major depressive disorder (MDD), and separation anxiety disorder (SAD) among preschool children with PTSD are common, just as it has been demonstrated in studies with older children. Therefore, it is of the most importance that assessment of
Sille Schandorph Løkkegaard,
Mette Elmose,
Ask Elklit
Scandinavian Journal of Child and Adolescent Psychiatry and Psychology , 39–51
Research Article
(insistence on sameness, lack of social engagement, and social processing difficulties); 2) heightened psychiatric comorbidities with internalizing disorders (anxiety, depression, and borderline personality traits); and 3) emotional dysregulation. These three domains reflect specific processes that may help to explain the underidentification of ASD in females via diagnostic overshadowing.Consideration of atypical symptom presentations, heightened comorbidities, and emotion regulation difficulties may help
Andrea Trubanova,
Katharine Donlon,
Nicole L. Kreiser,
Thomas H. Ollendick,
Susan W. White
Scandinavian Journal of Child and Adolescent Psychiatry and Psychology , ISSUE 2, 66–76
research-article
), investigated how adolescents receive and give compassion (18).
Neff’s construct of self-compassion has been shown to be associated with adolescent psychopathology (6, 9, 19-21). Difficulties in generating and experiencing compassion and caring are associated with psychiatric symptoms for adolescents such as depressive symptoms (correlations between .60 to .62) (6, 9, 19), suicidality (compassion explained 3.4% variance in suicidality) (20), and anxiety (correlations between .26 to .73) (9, 21). From a
Eva Henje,
Frida Carlberg Rindestig,
Paul Gilbert,
Inga Dennhag
Scandinavian Journal of Child and Adolescent Psychiatry and Psychology , 70–80
Research Article
28 % were boys and 72 % were girls. In line with the expectations, the initial comparison showed that adolescents reporting life-time suicide attempt had significantly higher scores on attachment anxiety and negative affectivity, and had significantly lower scores on attachment closeness, and both past and present social support. Further analyses stratified on gender, however, revealed unexpected results, as a high score on negative affectivity only was a significant risk factor for life-time
Tóra Petersen,
Ask Elklit
Scandinavian Journal of Child and Adolescent Psychiatry and Psychology , ISSUE 3, 106–114
research-article
diagnostic aid is the Child Behavior Checklist (CBCL) (8). The CBCL is an empirically derived broadband assessment tool of psychopathology with excellent psychometric properties that has been translated into over 100 languages and is an easy to use paper and pencil instrument. A body of research (9–12) and a meta-analysis (13) have shown very high correspondence between a unique profile of the CBCL consisting of elevations in the Attention, Anxiety/Depression and Aggression subscales greater than two
Amy Yule,
Maura Fitzgerald,
Timothy Wilens,
Janet Wozniak,
K. Yvonne Woodworth,
Alexa Pulli,
Mai Uchida,
Stephen V. Faraone,
Joseph Biederman
Scandinavian Journal of Child and Adolescent Psychiatry and Psychology
, 1–8
research-article
; significant mood change, hypomania/mania or depression; anxiety with depersonalization, derealization; hysteria), with concomitant reduction of epileptic activity in the EEG, and/or complete cessation of clinical seizures for at least 1 week. The expected EEG changes are very detailed (reduction in the total number of spikes counted in a 60-min. awake EEG recording by over 50% compared to a similar recording performed during a normal state of behavior and others. However, other EEG findings than spikes
Walter Fröscher,
Volker Faust,
Tilman Steinert
Journal of Epileptology , 7–13
Research Article
diverse symptomatology, including vegetative symptoms, suicidal ideation, anxiety, conduct problems, body dysmorphic symptoms, and deliberate vomiting. The classes predicted functional impairment in that the members of the second class showed more functional impairment.The relatively small sample size limited the generalizability of the results of this study, and the amount of items included in the analysis was restricted by the rules of latent class analysis. No conclusions about gender differences
Eva Henje Blom,
Mats Forsman,
Tony T. Yang,
Eva Serlachius,
Jan-Olov Larsson
Scandinavian Journal of Child and Adolescent Psychiatry and Psychology , ISSUE 1, 19–28