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Review

MeCP2 in central nervous system glial cells: current updates

have discussed the role of MeCP2 in glial subtypes, astrocytes, oligodendrocytes and microglia, and how loss of MeCP2 function in these cells has a profound influence on both glial and neuronal function.

Kedarlal Sharma, Juhi Singh, Emma E. Frost, Prakash P. Pillai

Acta Neurobiologiae Experimentalis , ISSUE 1, 30–40

Hypothesis

Do minocycline and other suppressors of microglia reactivity have a future in prevention or treatment of epilepsy?

will discuss new concepts of epileptogenesis which focus not only on changes in neurons but also take into consideration the role of activation of glial cells: microglia and astrocytes. Neuroinflammation, mainly through increased production of pro-inflammatory factors such as cytokines or chemokines, may play an important role in the development of epilepsy. Drugs regulating glial cells activation and consequently inflammatory status in the central nervous system have beneficial effects in

Władysław Lasoń, Joanna Ślusarczyk, Magdalena Regulska, Monika Leśkiewicz, Agnieszka Basta-Kaim

Journal of Epileptology , ISSUE 1-2, 9–20

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