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review-article | 05-September-2019

Cannabinoids in the treatment of epilepsy – an updated review

have fewer side effects. Many families choose to try non-pharmaceutical or alternative therapy options. Cannabis-based treatment for epilepsy has recently received prominent attention in the lay press and in social media. The reports of dramatic improvements in seizure control in children with severe epilepsy have been published (Gupta, 2013). An abundance of preclinical evidence and anecdotal human data support the use of cannabinoids in the treatment of epilepsy. AIM The present review paper

Marcin Kopka

Journal of Epileptology, Volume 27 , 35–42

Review Paper | 30-November-2015

The role of cannabinoids and endocannabinoid system in the treatment of epilepsy

Introduction. The treatment of epilepsy is still a major challenge. Despite the introduction of many new antiepileptic drugs, approximately 30% of patients still remain drug resistant. In the absence of a satisfactory therapy outcome, which is sometimes associated with numerous side effects, there is a need for new and effective drugs with low toxicity. Cannabinoids have been shown in preliminary animal model studies and in studies of patients with epilepsy to have antiepileptic activity. Aim

Monika Pędracka, Jacek Gawłowicz

Journal of Epileptology, Volume 23 , ISSUE 2, 131–138

Research paper | 29-September-2017

Interaction between urethane and cannabinoid CB1 receptor agonist and antagonist in penicillin-induced epileptiform activity

Gokhan Arslan, Sabiha Kubra Alici, Mustafa Ayyildiz, Erdal Agar

Acta Neurobiologiae Experimentalis, Volume 77 , ISSUE 2, 128–136

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