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Review Paper

Depression and anxiety in people with epilepsy: Why should we identify?

Introduction. People with epilepsy (PWE) have a higher risk of developing depression and anxiety than people without epilepsy. However, understanding and management of that issue remain under-recognized. Aim. To emphesize: a) the relationship between depression, anxiety, and epilepsy, and b) to suggest practical strategies for their identification by clinicians. Methods. The current literatures was reviewed investigating the impact of depression and anxiety in PWE and those examining the

Sung-Pa Park

Journal of Epileptology , ISSUE 1, 57–62

research-article

Validation of the Polish version of the Neurological Disorders Depression Inventory for Epilepsy (P-NDDI-E)

INTRODUCTION Patients with epilepsy (PWEs) have worse quality of life than individuals from the general population not only because of occurrence of epileptic seizures, but also due to comorbid psychiatric disorders, especially depression (Jacoby et al., 2009; Kanner et al., 2012a; Yue et al., 2011). These symptoms are severe and more frequent in population of patients with epilepsy than in the general population (Jalava and Sillanpää, 1996; Kwon and Park, 2014; Tellez-Zenteno et al., 2007

Bartłomiej Gmaj, Jerzy Majkowski, Jan Szczypiński, Joanna Jędrzejczak, Beata Majkowska-Zwolińska, Marcin Wojnar, Jacek Gawłowicz, Piotr Januszko, Sung Pa Park, Ewa Nagańska, Simon Ziemka, Dorota Wołyńczyk-Gmaj

Journal of Epileptology , ISSUE 1-2, 59–64

research-article

Alteration of oxidative stress markers and behavior of rats in a novel model of depression

INTRODUCTION Currently, the pathological role of stress in the genesis of neuropsychiatric disorders including depression is being actively studied. An important role has been assigned to emotional stress caused by the cognitive processing of negative stimuli (Yang et al., (2015). Experimental models of depression can be divided into several groups depending on methodology and type of influencing factor. The first group includes methods based on the effects of physical stress, which include the

Anna Gorlova, Dmitrii Pavlov, Eugene Zubkov, Yana Zorkina, Anatoly Inozemtsev, Anna Morozova, Vladimir Chekhonin

Acta Neurobiologiae Experimentalis , ISSUE 3, 232–238

short-report

The Effects of Social Support on the Relationship between Infant Sleep and Postnatal Depression

factors (parental soothing behaviors, maternal depression, parenting stress and parental sleep-related cognitions) (4, 5). As a result of these intrinsic and extrinsic factors, it has been shown that overnight crying and sleep problems can affect up to 30% of infants (6). Child sleep disturbance is important to consider because it may have aversive consequences for the child including developmental delay, behavioural problems and mood disorders (6), poor academic performance (7), and high levels of

Y King, S Blunden

Eat, Sleep, Work , ISSUE 1, 2–17

Research paper

The use of MR-less MNI based neuronavigation for 10 Hz rTMS depression therapy: electrophysiological and clinical implications

Repetitive transcranial magnetic stimulation (rTMS) is a popular and effective treatment for drug resistant depression. However, there is considerable variability in clinical outcomes, in previous studies and between patients. Because of high requirements for the use of fMRI based neuronavigation, many practitioners of rTMS still choose to use a standard 5 cm rule for rTMS coil placement which leads to large variations in which brain regions are being stimulated. We decided to test the

Vladas Valiulis, Giedrius Gerulskis, Kastytis Dapšys, Karolina Valavičiūtė, Aldona Šiurkutė, Valentinas Mačiulis

Acta Neurobiologiae Experimentalis , ISSUE 3, 271–280

research-paper

The effect of bupropion augmentation of minocycline in the treatment of depression

INTRODUCTION Depression is often considered as a common mental disorder of the brain encompassing feelings of sadness, guilt, loss of appetite, tiredness, lack of concentration, lack of self-esteem, lack of interest or pleasure, and disturbed sleep. Depression is common worldwide, with an estimated 300 million people affected. Depression adds to the global burden of disease (according to the World Health Organization). The antidepressants available are associated with adverse effects and a slow

Monica Bendale, Sharon Ronald D'souza, Veeranjaneyulu Addepalli, Pravin Popatrao Kale

Acta Neurobiologiae Experimentalis , ISSUE 2, 217–224

research-paper

Modulation of catalase, copper and zinc in the hippocampus and the prefrontal cortex in social isolation-induced depression in male rats

INTRODUCTION Depression is a psychiatric illness with diverse clinical manifestations. It’s presentation can include loss of sleep, appetite and sense of pleasure and loneliness (Kapfhammer, 2006). Moreover, in many neurological and psychiatric disorders, depression is found to be co morbid (Sherbourne et al., 1996; Moussavi et al., 2007; Raskind, 2008). In some cases, it manifests itself in periods of relapse (Morgan, 2003; Ma and Teasdale, 2004). Considering the burden of depression

Hamidreza Famitafreshi, Morteza Karimian

Acta Neurobiologiae Experimentalis , ISSUE 2, 184–192

research-article

Moderation of treatment effects by parent-adolescent conflict in a randomised controlled trial of Attachment-Based Family Therapy for adolescent depression

Introduction Adolescents who suffer from depression report experiencing more conflict and less support in the relationship with their parents (1). The transition into adolescence is normatively accompanied by increases in parent-child conflict (2), but not all parent-adolescent dyads manage these conflicts equally well (3). Parent-adolescent conflict has been linked to onset of adolescent depressive symptoms in multiple studies (4-6). Parent-adolescent conflict has further been found to predict

Erling W. Rognli, Luxsiya Waraan, Nikolai O. Czajkowski, Marianne Aalberg

Scandinavian Journal of Child and Adolescent Psychiatry and Psychology , 110–122

research-article

Repetitive Negative Thinking outperforms loneliness and lack of social connectedness as a predictor of prospective depressive symptoms in adolescents

Introduction Knowledge about reliable risk factors for depression is of critical importance, especially in adolescence, given (a) the high prevalence of both clinical and subsyndromal levels of depression in that period (1, 2) combined with (b) the well-documented detrimental and far-reaching consequences of adolescent depression later in life (3, 4) that even exist for subclinical levels of depression (5). The identification of risk factors, therefore, is crucial for targeted prevention. An

Filip Raes, Margot Bastin, Tina Pede, Eline Belmans, Luc Goossens, Janne Vanhalst

Scandinavian Journal of Child and Adolescent Psychiatry and Psychology , 149–156

Research paper

Detrimental effects of chia (Salvia hispanica L.) seeds on learning and memory in aluminum chloride-induced experimental Alzheimer’s disease

established (i.e., treatment). A battery of behavioral and cognitive tests were performed, including open-field, elevated plus maze, Porsolt’s forced swim, and Morris’ water maze, to evaluate anxietyand depression-like behaviors, and learning and memory. Results showed that chia supplementation was ineffective against Alzheimer’s-related anxiety, whereas depression-like behaviors were attenuated with both pretreatment and treatment. There was no improvement in learning and memory with chia treatment

Yasemin Bilgic, Enver Ahmet Demir, Nilufer Bilgic, Hatice Dogan, Okan Tutuk, Cemil Tumer

Acta Neurobiologiae Experimentalis , ISSUE 4, 322–331

Research paper

Anhedonia but not passive floating is an indicator of depressive‑like behavior in two chronic stress paradigms

Depression is the most common form of mental disability in the world. Depressive episodes may be precipitated by severe acute stressful events or by mild chronic stressors. Studies on the mechanisms of depression require both appropriate experimental models (most of them based on the exposure of animals to chronic stressors), and appropriate tests for assessment of depressive states. In this study male Wistar rats were exposed to two different chronic stress paradigms: an eight‑week chronic

Mikhail Yu. Stepanichev, Anna O. Tishkina, Margarita R. Novikova, Irina P. Levshina, Sofiya V. Freiman, Mikhail V. Onufriev, Olga A. Levchenko, Natalia A. Lazareva, Natalia V. Gulyaeva

Acta Neurobiologiae Experimentalis , ISSUE 4, 324–333

research-article

Subchronic effects of ligands of cannabinoid receptors on learning and memory processes of olfactory bulbectomized rats

(Ranieri et al., 2016). The bilateral olfactory bulbectomy (OBX) is a validated model of depression. The removal of bulbi olfactorii produces a syndrome of behavioral, neurochemical, neuroendocrine, immune, etc. alterations, that resembles human depressive disorder (Kelly et al., 1997; Song and Leonard, 2005). OBX causes long lasting neurodegenerative changes in many brain areas and therefore, it is suggested that it might be a valuable tool in the study of neurodegenerative disorders like Alzheimer’s

Margarita Velikova, Dobrinka Doncheva, Roman Tashev

Acta Neurobiologiae Experimentalis , ISSUE 3, 286–296

review-article

Pharmacological and non-pharmacological approaches to life threatening conditions in epilepsy

. In such situations, alternative agents are recommended. In case of phenobarbital, it is extremely important to monitor blood pressure, ECG and respiratory function. The latter function is of paramount importance since phenobarbital may induce respiratory depression. Therefore, it should be administered only if ventilator support is available. One of the requirements at this stage is informing a neurointensivist or experienced anaesthetist about the patient and his or her condition (Jones et al

Barbara Błaszczyk, Aleksandra Walczak, Natalia Ścirka, Agnieszka Konarzewska, Barbara Miziak, Stanisław J. Czuczwar

Journal of Epileptology , 15–26

Research paper

Assessment of type 1 and type 3 deiodinase expression levels in depressive disorders

A depressive disorder is a disease characterized by a heterogenous background. The important processes observed and diagnosed in depressed patients indicate that the etiology of depression may include disturbances in thyroid hormone (TH) levels and the occurrence of immune-inflammatory activation. Type 1 (DIO1) and type 3 (DIO3) iodothyronine deiodinases are the enzymes which determine the peripheral and tissue levels of TH, but also interfere with immunological cells and inflammatory processes

Elżbieta Gałecka, Anna Kumor-Kisielewska, Agata Orzechowska, Michael Maes, Paweł Górski, Janusz Szemraj

Acta Neurobiologiae Experimentalis , ISSUE 3, 225–235

short-report

Long-Term Evaluation of an Australian Peer Outdoor Support Therapy for Contemporary War Veterans

1. Introduction Each year in Australia, approximately 12,000 Australian Defence Force (ADF) personnel are deployed in military service (1). Mental health problems including Post-traumatic Stress Disorder (PTSD, i.e., a set of symptoms such as traumatic flashbacks, avoidance, feeling emotionally numb, negative thoughts and mood, and agitation) (1,2), anxiety (3) and depression (1) may develop in some personnel as a result of exposure to traumatic experiences during such service. In addition

S Cloete, L Chantler

Eat, Sleep, Work , 39–53

research-paper

Antidepressant and anxiolytic efficacy of single, chronic and concomitant use of vortioxetine, dapoxetine and fluoxetine in prenatally stressed rats

INTRODUCTION Depression is one of the most common and most disabling mental disorders characterised by a major burden on both the patients and society as a whole. The most common symptoms of depression include low mood, low self-esteem, sleeping disorders and anxieties, which together frequently lead to suicides. It should be noted that the incidence of both (depression and anxiety disorders) have been on the rise, which may be related to longer lifespans, unemployment, migrations

Piotr Ratajczak, Krzysztof Kus, Tomasz Zaprutko, Mikołaj Szczepański, Sandra Rusowicz, Elżbieta Nowakowska

Acta Neurobiologiae Experimentalis , ISSUE 1, 13–24

Research Article

Low self-esteem and high psychological distress are common among depressed adolescents presenting to the Pediatric Emergency Department

Background:Increasing psychiatric disorders and alcohol intoxication challenge the pediatric emergency departments (PEDs) to which adolescents are referred owing to acute alcohol intoxication.Objective:This study examined the degree to which adolescents presenting to PED with alcohol intoxication or deliberate self-harm report symptoms of depression and how they differed from non-depressed patients in terms of alcohol use, perceived social support, psychological distress, self-esteem, and

Varpu Puuskari, Terhi Aalto-Setälä, Erkki Komulainen, Mauri Marttunen

Scandinavian Journal of Child and Adolescent Psychiatry and Psychology , ISSUE 1, 39–49

research-article

Normative and negative sexual experiences of transgender identifying adolescents in the community

ever acted violently (for example by hitting, punching, hair-pulling or similar) towards a date or a steady partner?”, both with response alternatives “yes” and “no”. Confounding Confounding factors controlled for were age, sex, honesty of responding and depression. Age and sex Age was calculated from date of responding and date of birth and was used as a continuous variable in the analyses. Confounding by age needs to be controlled for because during adolescence, even small age differences may

Elias Heino, Sari Fröjd, Mauri Marttunen, Riittakerttu Kaltiala

Scandinavian Journal of Child and Adolescent Psychiatry and Psychology , 166–175

Research Article

Further evidence of high level of persistence of pediatric bipolar-I disorder from childhood onto young adulthood: a five-year follow up

Janet Wozniak, Rebecca Wolenski, Maura Fitzgerald, Stephen V. Faraone, Gagan Joshi, Mai Uchida, Joseph Biederman

Scandinavian Journal of Child and Adolescent Psychiatry and Psychology , ISSUE 1, 40–51

Review

Lithium – therapeutic tool endowed with multiple beneficiary effects caused by multiple mechanisms

Mood disorders are relatively common serious human diseases for which there is often no ideal pharmacotherapy. Basic characteristic of these diseases is affective disorder shifting the mood of the patient to depression (together with anxiety or not) or towards to euphoria. Available drugs are usually divided into two groups – mood stabilizers, which are used primarily to treat bipolar disorder,and antidepressants for the treatment of unipolar depression. Lithium is still recommended as the

Miroslava Vosahlikova, Petr Svoboda

Acta Neurobiologiae Experimentalis , ISSUE 1, 1–19

Research Article

Latent Classes of Symptoms related to Clinically Depressed Mood in Adolescents

The diagnosis of major depressive disorder (MDD), according to the Diagnostic and Statistical Manual of Mental Disorders, is based only on adult symptomatology of depression and not adapted for age and gender. This may contribute to the low diagnostic specificity and validity of adolescent MDD. In this study, we investigated whether latent classes based on symptoms associated with depressed mood could be identified in a sample of adolescents seeking psychiatric care, regardless of traditionally

Eva Henje Blom, Mats Forsman, Tony T. Yang, Eva Serlachius, Jan-Olov Larsson

Scandinavian Journal of Child and Adolescent Psychiatry and Psychology , ISSUE 1, 19–28

Research Article

Psychiatric problems and quality of life in a clinical sample of adolescents: The role of peer relations

problems, with particular focus on symptoms of anxiety, depression, and ADHD. We also examined the potential mediating role of peer problems in the relationship between such symptoms and QoL.Methods:The sample consisted of 603 adolescents (ages 13-18) referred to clinical assessment. Psychiatric diagnoses according to the criteria of the International Statistical Classification of Diseases and Related Health Problems, 10th revision, were collected from participants’ clinical charts. Symptoms of

Ingunn Ranøyen, Eva Gulliksrud, Marit S. Indredavik, Frode Stenseng

Scandinavian Journal of Child and Adolescent Psychiatry and Psychology , ISSUE 4, 183–192

research-paper

Prevention of cadmium-induced neurotoxicity in rats by essential nutrients present in nuts

levels. Fig. 1. Schematic representation of the experimental protocol followed in the current study. Forced swim test (FST); Light/dark transition test (LTD); Elevated plus maze (EPM); Morris water maze (MWM); Novel object recognition (NOR). Behavioral analysis Forced swim test (FST) Depressive behavior was tested in a glass tank (56 cm height and 30 cm width) using an established method for quantifying depression responses in rats (Haider et al., 2015). The apparatus was filled with water to a

Zehra Batool, Faiza Agha, Saiqa Tabassum, Tuba Sharf1 Batool, Rafat Ali Siddiqui, Saida Haider

Acta Neurobiologiae Experimentalis , ISSUE 2, 169–183

Review

The gut microbiota in neuropsychiatric disorders

brain and gut microflora have been shown. Recent findings suggest that specific bacteria can be involved in the development of clinical conditions, such as Autism Spectrum Disorders, depression and schizophrenia, and microbiota may be a target for therapeutic intervention providing novel treatment strategies.

Marta Grochowska, Marcin Wojnar, Marek Radkowski

Acta Neurobiologiae Experimentalis , ISSUE 2, 69–81

research-article

Morphological and molecular characterization of Epidorylaimus procerus sp. n. (Dorylaimida: Qudsianematidae) from Vietnam

Thi Anh Duong Nguyen, Reyes Peña-Santiago

Journal of Nematology , 1–8

research-article

Considering Causes for Hypoactive Delirium

lethargy” or “quiet delirium.” See Table 1. It manifests itself as decreased psychomotor activity, lethargy, inattention, slow responses to questions, and looks similar to depression and sedation (Bui, Pham, Shirkey, & Swan, 2017; Bush et al., 2017; Han et al., 2009; Wan, Kasliwal, McKenzie, & Barrett, 2011). As a result, it is often overlooked without a standardized delirium assessment (Han et al., 2009; Robinson, Raeburn, Tran, Brenner, & Moss, 2011; Zhang et al., 2016). Table 1. Delirium Subtypes

Malissa A Mulkey, Sonya R Hardin, DaiWai M Olson, Cindy L Munro, Erik Everhart

Australasian Journal of Neuroscience , ISSUE 1, 9–16

Research paper

USING THE DAY RECONSTRUCTION METHOD TO QUANTIFY TIME SPENT SUFFERING AMONG OLDER ADULTS WITH CHRONIC PAIN

also measure suffering from negative symptoms, such as pain and fatigue, in 122 older adults, most of whom suffer from chronic pain. Results indicated that the method was well tolerated in this population, with over 98% of the sample providing interpretable responses. Chronic pain respondents reported spending a considerable proportion of their day suffering from pain, fatigue, and depression; a much higher proportion than reported by healthy controls (p’s < .01). Time spent suffering was

Dylan M. Smith

Statistics in Transition New Series , ISSUE 3, 429–440

Research paper

The effects of edaravone in ketamine-induced model of mania in rats

Bipolar disorder is a chronic disease characterized by recurring episodes of mania and depression that can lead to disability. This study investigates the protective effects of edaravone (3-methyl-1-phenyl-2-pyrazolin-5-one), a drug with well-known antioxidant properties, in a model of mania induced by ketamine in rats. Locomotor activity was assessed in the open-field test. Superoxide dismutase (SOD), catalase (CAT) and thiobarbituric acid reactive substances (TBARS) levels were measured in

Filiz Civil Arslan, Ahmet Tiryaki, Mehmet Yıldırım, Evrim Özkorumak, Ahmet Alver, İlkay Keleş Altun, İmran İnce, Öznur Gedikli

Acta Neurobiologiae Experimentalis , ISSUE 3, 192–198

Research Article

Psychological Difficulties among Children and Adolescents with Ethnic Danish, Immigrant, and Refugee Backgrounds

This study investigated and compared the prevalence of psychological difficulties among Danish, immigrant, and refugee children.We enrolled 332 children between the ages of 8 and 18 years (148 Danish children, 81 immigrant children, and 67 children with refugee backgrounds), all from low-income areas of residence. The Health Behaviour in School-aged Children Symptoms Checklist, the Strengths and Difficulties Questionnaire, and the Revised Children’s Anxiety and Depression Scale were applied.We

Ingrid Leth, Janni Niclasen, Else Ryding, Yasmine Baroud, Barbara H. Esbjørn

Scandinavian Journal of Child and Adolescent Psychiatry and Psychology , ISSUE 1, 29–37

Research Article

Identity formation and evaluation in adolescence and emerging adulthood: How is it associated with depressive symptoms and loneliness?

Ruminative Exploration, were significantly associated with depression. None of the five identity dimensions were associated with loneliness.Conclusions:The findings suggest that the identity dimensions are not specifically associated with feelings of loneliness but that Identification with Commitment and Ruminative Exploration may be key components in the development of depressive symptoms. Future studies exploring the associations of identity dimensions and multiple intra- and interpersonal aspects of

Nanna Lindekilde, Marlene Lübeck, Mathias Lasgaard

Scandinavian Journal of Child and Adolescent Psychiatry and Psychology , ISSUE 2, 91–97

Article

Paurodontella parapitica n. sp. (Nematoda: Hexatylina, Sphaerularioidea) from Kermanshah Province, Western Iran

Paurodontella parapitica n. sp., collected from the rhizosphere of an apple tree in Kermanshah province, western Iran, is described. The new species is characterized by a body length of 505 to 723 mm (females) and 480 to 600 mm (males), lip region continuous by depression; 7 to 8 mm broad, 3 to 4 mm high, stylet length 7 to 9 mm or 1 to 1.3 times the lip region diameter, short postuterine sac of 4 to 6 mm long, lateral fields with five to six incisures; outer incisures crenated and

MEHRAB ESMAEILI, RAMIN HEYDARI, WEIMIN YE

Journal of Nematology , ISSUE 2, 109–115

Review

The role of DSCAM in the regulation of synaptic plasticity: possible involvement in neuropsychiatric disorders

Synaptic plasticity simply put, is the activity-dependent modification of the strength or efficacy of synaptic transmission in the network of synapses in the brain. The role of synaptic plasticity in disease is an active area of research. Changes in plasticity translate to the release of neurotransmitters at the synapse and subsequently, the way humans see the world. It is known that neuropsychiatric disorders such as depression, posttraumatic stress disorder (PTSD), and Alzheimer’s disease (AD

Katarzyna Stachowicz

Acta Neurobiologiae Experimentalis , ISSUE 3, 210–219

research-article

Differential expression of the c-fos protein and synaptophysin in zebrin II positive and zebrin II negative cerebellar cortical areas in 4-aminopyridine seizures

suggest that this mechanism is more pronounced in the Z(+) zones due to the reciprocal forebrain connections, which elicit enhanced GLU release from the CFs (Paukert et al., 2010). Indeed, the present results demonstrate (1) a depression of c-fos expression in the PCs during convulsions, and (2) that PCs are not significantly activated, despite a significant rise in c-fos protein expression in the granule cells and interneurons of the molecular layer. The properties of the CF system cannot explain the

Beáta Krisztin-Péva, András Mihály, Zoltán Tóth

Acta Neurobiologiae Experimentalis , ISSUE 3, 239–251

Research paper

Effects of individual stressors used in a battery of “chronic unpredictable stress” on long-term plasticity in the hippocampus of juvenile rats

We have studied alterations in the properties of long-term potentiation (LTP) in hippocampal slices of juvenile rats induced by the exposure of animals to different individual stressors usually used in batteries of chronic unpredictable stress (CUS), a widely used model of depression. Social isolation for 16 h did substantially affect neither the magnitude and nor the development of LTP. The effects of stroboscopic illumination and water deprivation appeared most severe, though opposite: the

Alexandra A. Gorbunova, Irina V. Kudryashova, Anna O. Manolova, Margarita R. Novikova, Mikhail Yu. Stepanichev, Natalia V. Gulyaeva

Acta Neurobiologiae Experimentalis , ISSUE 3, 244–253

research-article

A BRIEF UPDATE ON PSYCHOGENIC NON-EPILEPTIC SEIZURES: A CHALLENGE TO OVERCOME

data exist on the role of single signs or symptoms in confirming or excluding PNES, as sensitivity and specificity are generally suboptimal. Prolactin and creatinkinase are reliable serum biomarkers, as normal values within a few hours after an episode may help confirm the diagnosis of PNES. However, the sole normality of these levels does not exclude the diagnosis of ES. Many psychiatric conditions are common in people with PNES, including depression, anxiety, post-traumatic stress disorders

Massimiliano Beghi, Cesare Maria Cornaggia, Ettore Beghi

Journal of Epileptology , 27–32

Case report

Treatment efficacy of narrative family therapy for children and adolescents with diverse psychiatric symptomatology

found a significant increase in median BYI measures of Self-Concept (40.5 to 46.0, p = 0.002) with an effect size of 0.60, decreases in BYI Depression Index (58.0 to 54.0, p = 0.030) with an effect size of –0.41, decreases in BYI Disruptive Behaviour Index (48.0 to 43.0, p = 0.030) with an effect size of –0.38, and a significant increase in PAM from 56.4 to 68.5, p = 0.001 with an effect size of 0.61.Conclusion:Results from this study suggest that NFT has a direct positive effect on patients’ own

Nina Tejs Jørring, Karsten Gjessing Jensen

Scandinavian Journal of Child and Adolescent Psychiatry and Psychology , ISSUE 2, 107–114

research-article

Cell-based immunofluorescence assay for screening the neurogenesis potential of new drugs in adult hippocampal neural progenitor cells

disorders. Some symptoms of these diseases can be explained by the dysregulation of adult neurogenesis (Winner and Winkler, 2015; Toda et al., 2019). Preclinical studies have suggested that increased adult neurogenesis in the hippocampus has potential therapeutic benefits in patients with Alzheimer’s disease and depression (Iqbal and Grundke-Iqbal, 2011; Miller and Hen, 2015; Han et al., 2016). This has led to adult neurogenesis as a target for the treatment of some brain diseases. Several methods can

Kun Zhang, Bin Li, Peifang Li, Xiaoli Yang, Huixian Cui, Xiaoyun Liu

Acta Neurobiologiae Experimentalis , ISSUE 3, 303–309

research-article

Aerobic exercise has an anxiolytic effect on streptozotocin-induced diabetic rats

, 2004). Diabetes has many complications including cardiomyopathy, retinopathy, neuropathy, nephropathy (American Diabetes Association, 2010), as well as affecting the mental status of the patients. Various psychological comorbidities, such as depression and anxiety, are associated with diabetes (Ducat et al., 2014) and the prognosis is worse in patients with poor glycemic control (Lustman et al., 2000). In addition to clinical studies, behavioral alterations were demonstrated in experimental models

Hasan Caliskan, Firat Akat, Goktug Omercioglu, Gulbahar Bastug, Hakan Ficicilar, Metin Bastug

Acta Neurobiologiae Experimentalis , ISSUE 3, 245–255

research-article

Description of a new dagger nematode, Xiphinema barooghii n. sp. (Nematoda: Longidoridae) and additional data on the three known species of the genus from northwest of Iran

and very fine transverse striations are visible more in tail region, 3.0‒4.0 μm wide at mid-body and 11‒16 μm at the tail tip. Lateral pores are present along the body, with four dorsal and five ventral located between anterior end and guiding ring. Lateral chords of 14‒17 μm or those occupying one-fifth of the mid-body diameter are present. The lip region is flat and the cephalic region is rounded, separated from body contour by a shallow depression, 1.7‒2.5 times as broad as high and one-fourth

Nasir Vazifeh, Gholamreza Niknam, Habibeh Jabbari, Arezoo Naghavi

Journal of Nematology , 1–17

research-article

Data of an Iranian Population of L. proximus Sturhan & Argo, 1983, with taxonomic revision of L. israelensis Peneva, Orion, Shlevin, Bar-Eyal & Brown, 1998 (Nematoda: Longidoridae) and Proposal for a New Synonymy

, western Iran. GPS coordinates: N 34˚54′12.63″, E 48˚31′03.84″. Females Body slender, gradually tapering toward the anterior end, curved into C-shape on relaxation. Cuticle 3.5 to 5.5 µm thick in the anterior region at level with the guiding ring, 3.7 to 4.6 µm thick at the mid-body, 4.5 to 7.0 µm thick at the anus, and 15 to 21 µm thick at the tail end. Lip region expanded, rounded at the corners, separated from the rest of the body by a shallow depression. Amphidial fovea pocket-shaped, their base

Mazdosht Giti, Leila Kashi, Majid Pedram

journal of nematology , 1–11

research article

One-year follow-up of The Incredible Years Parents and Babies Program: A pilot randomized controlled trial

its highest in the early years (6). In addition, infants are exposed to more potentially damaging experiences such as child neglect and violent abuse than older children (6–10). Compared to older children, infants are also more sensitive to disruptions in parental care. Infants with mothers suffering from depression or severe stress can show biochemical, physiological, and behavioral dysregulations beginning shortly after birth, and may be at increased risk of mental and behavioral problems (11–13

Maiken Pontoppidan, Tróndur Møller Sandoy, Sihu K. Klest

Scandinavian Journal of Child and Adolescent Psychiatry and Psychology , 123–134

Research paper

EEG source activity during processing of neutral stimuli in subjects with anxiety disorders

patients with anxiety disorders committed more errors than the controls, had a short latency of P300 and higher amplitude of ERPs at all steps of stimulus processing. Furthermore, we showed that there was a relationship between the scores of Hamilton Anxiety Scale and Beck Depression Inventory, and amplitudes and latencies of ERPs. The results of LORETA analysis showed that enhanced neural responses were found within circuits mediating visual information processing, sustained

Bartłomiej Gmaj, Piotr Januszko, Jan Kamiński, Ewa Drozdowicz, Maciej Kopera, Dorota Wołyńczyk-Gmaj, Waldemar Szelenberger, Marcin Wojnar

Acta Neurobiologiae Experimentalis , ISSUE 1, 75–85

Review Paper

The epileptic multifactorial patient’s burden. Review of the topic

decreased quality of life. Decreased self-esteem and major stigma are also frequent, linked to social, economic and personal negative consequences. Age also plays a role, younger people being more stigmatized given the interdiction to drive or difficulty in getting a job. In the elderly, seizures may have an impact on mental status, mood and sleep. Gender may also contribute, particularly involving women in childbearing age, linked to the fear or depression due to the possibility of AED-induced

José Pimentel

Journal of Epileptology , ISSUE 2, 167–172

Research Article

Underidentification of Autism Spectrum Disorder in Females: A Case Series Illustrating the Unique Presentation of this Disorder in Young Women

(insistence on sameness, lack of social engagement, and social processing difficulties); 2) heightened psychiatric comorbidities with internalizing disorders (anxiety, depression, and borderline personality traits); and 3) emotional dysregulation. These three domains reflect specific processes that may help to explain the underidentification of ASD in females via diagnostic overshadowing.Consideration of atypical symptom presentations, heightened comorbidities, and emotion regulation difficulties may help

Andrea Trubanova, Katharine Donlon, Nicole L. Kreiser, Thomas H. Ollendick, Susan W. White

Scandinavian Journal of Child and Adolescent Psychiatry and Psychology , ISSUE 2, 66–76

Research Article

Description of Aphelenchoides giblindavisi n. sp. (Nematoda: Aphelenchoididae), and Proposal for a New Combination

separated from the rest body by a shallow depression, 10 to 11 μm long stylet with small basal swellings, its conus shorter than the shaft (m = 36–43), 52 to 69 µm long postvulval uterine sac (PUS), males with 16 to 18 μm long arcuate spicules, and three pairs of caudal papillae. The new species was morphologically compared with two species of the genus having five lines in the lateral fields namely A. paramonovi and A. shamimi and species having a warty-surfaced mucro at tail end and similar

Farzad Aliramaji, Ebrahim Pourjam, Sergio Álvarez-Ortega, Farahnaz Jahanshahi Afshar, Majid Pedram

Journal of Nematology , ISSUE 3, 437–452

Research paper

Effects of social stress and clomipramine on emotional memory in mice

We have previously observed impairing effects of social defeat stress (CSDS) on inhibitory avoidance (IA) in mice. Given the similarity between changes produced by social stress in animals and symptoms of certain human psychopathologies such as depression and anxiety, the effects of the antidepressant clomipramine on IA impairment produced by CSDS were evaluated in the present study. Male CD1 mice were randomly assigned to the groups: non-stressed+saline, non-stressed+clomipramine, stressed

Aranzazu Duque, Concepción Vinader-Caerols, Santiago Monleón

Acta Neurobiologiae Experimentalis , ISSUE 3, 225–233

research-article

The influence of clinical and immune variables on psychopathological syndromes in partial epilepsies in relation to handedness

BACKGROUND Epilepsy represents neurological disease with a broad palette of concomitant psychopathological disorders. These disorders cause additional issues in the life of patients with epilepsy and make worse their social and clinical prognosis. The range of psychopathological disorders spreads from affective disorders, including depression and anxiety, to severe psychosis and mental deterioration that demands the precise and rapid diagnostics and adequate treatment. At present several

Vladimir V. Kalinin, Elena V. Zheleznova, Kirill Y. Subbotin, Natalia G. Yermakova, Anna A. Zemlyanaya, Lyudmila V. Sokolova

Journal of Epileptology , 17–25

research-article

A new rare nematode Nothocriconemoides hangzhouensis n. sp. (Nematoda: Criconematidae) from Hangzhou, China

. A: Entire body; B-D: En face view; E: Cuticle markings; F-H: tail regions arrows pointing on vulva (v) and anus (a) (Scale bars, A = 100 μm; B, C = 10 μm; D, H = 20 μm; G-F = 30 μm). Male Not found. Juveniles (n=5) Except for the cephalic region, they are similar to females; cephalic region of juveniles are devoid of collar-shaped annuli. Two rounded annuli are present and the first annulus show slight depression in the middle. Body annuli are narrower (4.5-5.5), slightly higher in number

Munawar Maria, Wentao Miao, Ruihang Cai, Pablo Castillo, Jingwu Zheng

Journal of Nematology , 1–14

research-article

Psychometric validity of the Compassionate Engagement and Action Scale for Adolescents: a Swedish version

-point Likert scale ranging from 0 (Never) to 3 (Always) (35). In this study we used only the depression and anger subscales. Depression (6, 9, 19) and anger are inversely related to self-compassion: Beck Youth Inventories of Emotional and Social Impairment Depression (BYI-D). The subscale consists of 20 questions. Internal consistency in the present sample was very high at .92 (95% CI = [.91, .94]). Beck Youth Inventories of Emotional and Social Impairment Anger (BYI-A). The internal consistency

Eva Henje, Frida Carlberg Rindestig, Paul Gilbert, Inga Dennhag

Scandinavian Journal of Child and Adolescent Psychiatry and Psychology , 70–80

Research paper

Narcolepsy type 1 and hypersomnia associated with a psychiatric disorder show different slow wave activity dynamics

The aim of the study was to compare electrophysiological parameters of night sleep in narcolepsy type 1 and hypersomnia associated with a psychiatric disorder. Forty-four patients: 15 with narcolepsy type 1, 14 with hypersomnia associated with a psychiatric disorder and 15 age- and sex-matched controls participated in the study. The study subjects filled in the Athens Insomnia Scale (AIS) and the Beck Depression Inventory (BDI). The severity of daytime sleepiness was quantified subjectively

Ewa Walacik-Ufnal, Anna Justyna Piotrowska, Dorota Wołyńczyk-Gmaj, Piotr Januszko, Bartłomiej Gmaj, Marcin Ufnal, Marek Kabat, Marcin Wojnar

Acta Neurobiologiae Experimentalis , ISSUE 2, 147–156

research-article

Further evidence of the Diagnostic Utility of the Child Behavior Checklist for identifying pediatric Bipolar I Disorder

diagnostic aid is the Child Behavior Checklist (CBCL) (8). The CBCL is an empirically derived broadband assessment tool of psychopathology with excellent psychometric properties that has been translated into over 100 languages and is an easy to use paper and pencil instrument. A body of research (9–12) and a meta-analysis (13) have shown very high correspondence between a unique profile of the CBCL consisting of elevations in the Attention, Anxiety/Depression and Aggression subscales greater than two

Amy Yule, Maura Fitzgerald, Timothy Wilens, Janet Wozniak, K. Yvonne Woodworth, Alexa Pulli, Mai Uchida, Stephen V. Faraone, Joseph Biederman

Scandinavian Journal of Child and Adolescent Psychiatry and Psychology , 1–8

research-article

Morphological and molecular characterization of Ektaphelenchoides pini (Massey, 1966) Baujard, 1984 (Aphelenchoididae; Ektaphelenchinae) from Iran, with morphological and taxonomic observations on some species

24 length (19–22) (22–28) (21–26) Capitulum width – 5.6 ± 0.5 – – – – (5-6) Note: All measurements are in μm and in the form: mean ± s.d. (range). Female Large nematodes. Body is slightly ventrally curved after fixation. Cuticle is finely annulated. Lateral fields have three incisures. Cephalic region is slightly set off from the body by a shallow depression. Stylet is well developed, its lumen is wide, and the conus is ca 38% of the total length with thick sclerotized

Fariba Heydari, Majid Pedram

Journal of Nematology , 1–12

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