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Article

Anti-Vel alloimmunization and severe hemolytic disease of the fetus and newborn

The Vel red blood cell (RBC) antigen was first described in 1952.1 The antigen is ubiquitous in the general population, with only 0.04 percent of Caucasian individuals failing to exhibit expression.2 Only rare cases of anti-Vel–associated mild-to-moderate hemolytic disease of the fetus and newborn (HDFN) have been previously reported.3–7 The neonatal manifestation of HDFN in these cases was limited to hyperbilirubinemia requiring only phototherapy. No case of fetal anemia requiring prenatal

K.J. Moise, Y. Morales, M.F. Bertholf, S.N. Rossmann, Y. Bai

Immunohematology , ISSUE 4, 152–154

original-paper

Campylobacter fetus is Internalized by Bovine Endometrial Epithelial Cells

Introduction Campylobacter fetus is a microaerophilic, Gram-negative bacterium that causes embryonic mortality, abnormal estrus cycles, reduced fertility and abortions in 5–10% of cases in cattle and sheep. C. fetus is divided into three subspecies: C. fetus subsp. fetus, C. fetus subsp. venerealis, and C. fetus subsp. testudinum. C. fetus subsp. venerealis is the etiologic agent of bovine genital campylobacteriosis, which causes infertility, abortions and embryonic death, and is mainly

LIZETH GUADALUPE CAMPOS-MÚZQUIZ, ESTELA TERESITA MÉNDEZ-OLVERA, BEATRIZ ARELLANO-REYNOSO, DANIEL MARTÍNEZ-GÓMEZ

Polish Journal of Microbiology , ISSUE 2, 217–224

Case report

A twin pregnancy with a hydatidiform mole and a coexisting live fetus: prenatal diagnosis, treatment, and follow-up

Twin molar pregnancy with a hydatidiform mole and a coexisting live fetus is a rare form of gestational trophoblastic disease associated with an increased risk of obstetric complications and poor perinatal outcome. Prenatal diagnosis is essential for couple counseling and follow-up in Tertiary Reference Centers. Magnetic resonance imaging is important for the diagnostic differentiation of placental mesenchymal dysplasia and exclusion of myometrial invasion. Here we present a case of twin molar

Antonio Braga, Bruna Obeica, Heron Werner, Sue Yazaki Sun, Joffre Amim Júnior, Jorge Rezende Filho, Edward Araujo Júnior

Journal of Ultrasonography , ISSUE 71, 299–305

Case report

Fetal ultrasound: Early diagnosis and natural evolution of proximal femoral focal deficiency

Eugenio O. Gerscovich, Simran Sekhon, Thomas W. Loehfelm, Adam Greenspan

Journal of Ultrasonography , ISSUE 71, 294–298

case-report

Prenatal diagnosis of congenitally corrected transposition of the great arteries

Nathalie Jeanne Bravo-Valenzuela, Alberto Borges Peixoto, Edward Araujo Júnior

Journal of Ultrasonography , ISSUE 79, 314–317

research-paper

Autism spectrum disorder and mercury toxicity: use of genomic and epigenetic methods to solve the etiologic puzzle

, half of which is derived from maternal inheritance. Thus, the role of paternal genetics would be to increase or decrease vulnerability to mercury toxicity through impacting the fetal genome. Fetal and infant genetics determine the degree of toxicity derived from gestational and postpartum mercury exposure. The fetus or infant, therefore, is exposed to maternal genetic risks in two ways: 1)Maternally derived in utero mercury exposure related to maternal genetics and the mother’s exposure to mercury

Mark E. McCaulley

Acta Neurobiologiae Experimentalis , ISSUE 2, 113–125

Case report

Body stalk anomaly: antenatal sonographic diagnosis of this rare entity with review of literature

phenomenon. Sonographic features of the fetus included a severe midline defect of the fetal abdominal wall with a large extra-abdominal mass containing bowel and liver inside. Body stalk anomaly is accepted as a fatal anomaly, so it is important to differentiate it from other anterior wall defects for evaluating the management options.

Amandeep Singh, Jasmeet Singh, Kamlesh Gupta

Journal of Ultrasonography , ISSUE 69, 133–135

Article

AUTOMATIC FETAL ORGANS DETECTION AND APPROXIMATION IN ULTRASOUND IMAGE

This paper proposed a system for detecting and approximating of a fetus in an ultrasound image. The fetal organs in the ultrasound image are detected using Multi Boundary Classifier based Adaboost.MH. The results of the fetal detection is then approximated Randomized Hough Transform and the whole showed a mean accuracy of 95.80%. The mean of the Hamming Error 0.019 and the Kappa coefficient value reaches 0.890.The proposed method has the best performancefor fetal organ detection. This is proven

M. Anwar Ma’sum, Wisnu Jatmiko, Budi Wiweko, Anom Bowolaksono

International Journal on Smart Sensing and Intelligent Systems , ISSUE 1, 720–748

Case report

Postpartum acute hemolytic transfusion reactions associated with anti-Lea in two pregnancies complicated by preeclampsia

, red blood cell units, compatible by electronic crossmatch, were issued and transfused. The subsequent transfusion reactions were characterized by acute intravascular hemolysis, evidenced by both clinical and laboratory criteria. These two cases demonstrate that, even when least anticipated, hemolytic transfusion reactions may occur. As expected, neither live-born neonate was affected by hemolytic disease of the fetus and newborn. Because both transfusion reactions occurred in non–group O

Marcia Marchese

Immunohematology , ISSUE 3, 114–118

Review

The Augustine blood group system, 48 years in the making

phenotype, has only been found in individuals of African origin. Anti-Ata has been implicated in immediate and delayed hemolytic transfusion reactions, but not in severe hemolytic disease of the fetus and newborn. The Augustine gene is SLC29A1, which encodes the equilibrative nucleoside transporter ENT1. At(a–) (AUG:–1,2) results from homozygosity for c.1171G>A, encoding Glu391Lys, whereas the AUGnull (AUG:–1,–2) phenotype results from homozygosity for a splice site mutation

Geoffrey Daniels

Immunohematology , ISSUE 3, 100–103

Review

The Vel blood group system: a review

. Clinically, anti-Vel is important and has caused severe transfusion reactions, although hemolytic disease of the fetus and newborn caused by anti-Vel is uncommon. However, while screening for Vel– blood donors has become easier, the function of SMIM1 is still unknown, and despite its well-conserved sequence across the animal kingdom, the enigma continues.

Jill R. Storry, Thierry Peyrard

Immunohematology , ISSUE 2, 56–59

Case report

A LU:−16 individual with antibodies

>T (LU:–16), and a silent polymorphism c.1227G>T. Anti-Lu16 was highly suspected. This would be the fifth case of LU:–16 with antibodies reported, all within women of African heritage with the Lu(a+b−) phenotype. Hemolytic disease of the fetus and newborn was not noted in these cases.

Carole Éthier, Cynthia Parent, Anne-Sophie Lemay, Nadia Baillargeon, Geneviève Laflamme, Josée Lavoie, Josée Perreault, Maryse St-Louis

Immunohematology , ISSUE 3, 110–113

Review Article

Current knowledge on the use of ultrasound measurements of fetal soft tissues for the assessment of pregnancy development

Ultrasonography, with its detailed imaging of the fetus, is very widely used in obstetrics. The primary aim of ultrasound scanning in pregnancy is to limit the risk of obstetric complications by early detection of abnormalities, such as intrauterine growth restriction and macrosomia. Currently, morphometric formulae are used for estimating fetal weight. They utilize basic biometric parameters. However, Hadlock formula, used for fetal weight estimation, has an error rate of 20%. For this reason

Aleksandra Warska, Anna Maliszewska, Anna Wnuk, Beata Szyszka, Włodzimierz Sawicki, Krzysztof Cendrowski

Journal of Ultrasonography , ISSUE 72, 50–55

Case report

Two cases of the variant RHD*DAU5 allele associated with maternal alloanti-D  

Rh is a complex blood group system with diverse genotypes that may encode weak and partial D variants. Standard serologic analysis may identify clinically significant D variants as D+; nevertheless, individuals with these D variants should be managed as D– patients to prevent antibody formation to absent D epitopes. Variant identification is necessary during pregnancy to allow for timely and appropriate Rh immune globulin (RhIG) prophylaxis for hemolytic disease of the fetus and newborn

Jennifer A. Duncan, Susan Nahirniak, Rodrigo Onell, Gwen Clarke

Immunohematology , ISSUE 2, 60–63

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