Mini Review | 07-June-2016
Flavonoids constitute a large group of polyphenolic compounds naturally found in plants, which have a wide range of biological activity. Although flavonoids are beneficial to human health, their application is limited by their low bioavailability and poor water-solubility. Therefore, recently there has been a particular interest in glycosylated forms of flavonoids, which usually are better soluble, more stable, and more functional compared to their aglycones. Microbial transformation of natural
Sandra Sordon,
Jarosław Popłoński,
Ewa Huszcza
Polish Journal of Microbiology, Volume 65 , ISSUE 2, 137–151
research-article | 24-June-2021
properties as adjuncts to standard antiepileptic drugs in the DRE treatment and flavonoids and may be a potential group of natural drugs that increase the effects of commonly used anticonvulsants.
Flavonoids, a class of secondary plant metabolites, have been shown to demonstrate a wide spectrum of biological activity, among others antioxidant (Santos et al., 1999), anti-inflammatory (Pintho et al., 2016), anti-allergic (Kawai et al., 2006), antiatherosclerotic (Goldwasser et al., 2011), antidiabetic
Joanna Szala-Rycaj,
Mirosław Zagaja,
Aleksandra Szewczyk,
Marta Andres-Mach
Acta Neurobiologiae Experimentalis, Volume 81 , ISSUE 2, 95–104
Review Paper | 04-December-2013
Introduction. Flavonoids are a large group of natural compounds that have been considered to be beneficial in ameliorating some age-dependent disorders. However, a potential use of these compounds in epilepsy treatment has not been systematically reviewed. Aim. This review describes the pharmacological activity of some polyphenols (flavonoids) in different animal models of seizures e.g. pentylenetetrazole-induced seizures, kainate-induced seizures and pentylenetetrazole kindling in rats. Method
Władysław Lasoń,
Monika Leśkiewicz
Journal of Epileptology, Volume 21 , ISSUE 2, 79–87