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Review Paper | 26-March-2014

Selected classical and novel antiepileptic drugs – mechanisms of action, neuroprotection, and effectiveness in epileptic and non-epileptic conditions

drugs (AEDs – lamotrigine, topiramate, levetiracetam, valproate and carbamazepine). Methods. A literature search for publications written in English, preferably published within a period of the last fifteen years, using the key words listed below. Review. The majority of AEDs possess more than one mechanism of action. They exert their effect by acting on various receptors (different types of glutamatergic and mainly GABAA receptors), neurotransmitters (mainly glutamate or GABA) and voltage

Magdalena Chrościńska-Krawczyk, Magdalena Wałek, Bożydar Tylus, Stanisław J. Czuczwar

Journal of Epileptology, Volume 22 , ISSUE 1, 37–50

Research paper | 31-July-2017

Age‑dependent concomitant changes in synaptic function and GABAergic pathway in the APP/PS1 mouse model

Tutu Oyelami, An De Bondt, Ilse Van den Wyngaert, Kirsten Van Hoorde, Luc Hoskens, Hamdy Shaban, John A. Kemp, Wilhelmus H. Drinkenburg

Acta Neurobiologiae Experimentalis, Volume 76 , ISSUE 4, 282–293

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