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research-article | 04-January-2021

Before the damage is done: Early childhood hyperactivity difficulties in adolescents with deliberate self-harm – findings from the DALSC cohort

the individual’s psychosocial development. It is therefore important to be aware of early risk factors across domains along with their interactions in order to design prevention and intervention programs for DSH (39). A distal vulnerability factor for the development of DSH could be hyperactivity difficulties which have a significant impact on a person’s psychosocial development. Hyperactivity is probably dimensionally distributed in the population (40) but hyperactivity difficulties have

Therese A. Evald, Bo Møhl

Scandinavian Journal of Child and Adolescent Psychiatry and Psychology, Volume 8 , 176–188

Research Article | 30-November-2013

Secondhand Smoke Exposure and Severity of Attention-Deficit/Hyperactivity Disorder in Preschoolers: A Pilot Investigation

Less is known about the effects of secondhand smoke (SHS) on mental health as compared with other medical disorders.The aims of this study were to examine the following: 1) the association of SHS exposure with childhood attention-deficit/hyperactivity (ADHD) and disruptive disorders; and 2) the association of maternal recall of a child’s SHS exposure and that child’s exposure as measured by bioassay.Sixty children had their saliva collected and assayed for cotinine when they were 4 years old

Mini Tandon, Christina N. Lessov-Schlaggar, Rebecca Tillman, Melbourne F. Hovell, Joan Luby

Scandinavian Journal of Child and Adolescent Psychiatry and Psychology, Volume 2 , ISSUE 1, 37–40

research-article | 07-July-2020

Putative shared mechanisms in autism spectrum disorders and attention deficit hyperactivity disorder, a systematic review of the role of oxidative stress

INTRODUCTION Autism spectrum disorders (ASD) are a heterogeneous group of neurodevelopmental disorders characterized by impairments in communication and in reciprocal social interaction along with restrictive and repetitive behaviours (American Psychiatric Association, 2013). Questions regarding the etiopathological mechanism of this complex disorder remain unanswered (Lai et al., 2014; Happe et al., 2006; Antshel and Russo, 2019). Attention deficit hyperactivity disorder (ADHD) is a frequent

Filipa Sa-Carneiro, Conceição Calhau, Rui Coelho, Margarida Figueiredo-Braga

Acta Neurobiologiae Experimentalis, Volume 80 , ISSUE 2, 129–138

Research Article | 30-November-2015

Are Autistic Traits in Youth Meaningful? A Replication study in Non-referred Siblings of Youth with and without Attention-Deficit/Hyperactivity Disorder

We previously described the high prevalence and burden of significant autistic traits (ATs) in youth with attention-deficit/hyperactivity disorder (ADHD). These traits are associated with significantly greater impairment in psychopathological, interpersonal, educational, and neuropsychological functioning. Because the sample consisted of referred ADHD youth, uncertainty remained regarding whether these findings are generalizable to non-referred populations of youths with and without ADHD.The

Joseph Biederman, Maura Fitzgerald, Stephen V. Faraone, Ronna Fried, K. Yvonne Woodworth, Alexandra Saunders, Kristina Conroy, Gagan Joshi

Scandinavian Journal of Child and Adolescent Psychiatry and Psychology, Volume 4 , ISSUE 2, 77–87

Review | 10-July-2018

Hallucinations and other psychotic symptoms in response to methylphenidate in children and adolescents with attention-deficit/hyperactivity disorder: a Cochrane systematic review with meta-analysis and trial sequential analysis#

Background:There is little evidence in the literature on the association between methylphenidate treatment and psychotic symptoms in children and adolescents with attention-deficit/hyperactivity disorder (ADHD).Objective:We examine the occurrence of psychotic symptoms during methylphenidate treatment of children and adolescents with ADHD. The data arise from our two Cochrane systematic reviews on methylphenidate, reported elsewhere.Methods:Electronic databases were searched up to January 2016

Erica Ramstad, Ole Jakob Storebø, Trine Gerner, Helle B. Krogh, Mathilde Holmskov, Frederik L. Magnusson, Carlos R. Moreira-Maia, Maria Skoog, Camilla Groth, Donna Gillies, Morris Zwi, Richard Kirubakaran, Christian Gluud, Erik Simonsen

Scandinavian Journal of Child and Adolescent Psychiatry and Psychology, Volume 6 , ISSUE 1, 52–71

Research Article | 30-November-2013

Impairment in Young Preschool Children with Symptoms of Attention-Deficit/Hyperactivity Disorder and Co-occurring Oppositional Defiant Disorder and Conduct Disorder

We have limited knowledge of the impact of attention-deficit/hyperactivity disorder (ADHD) symptoms on the daily functioning of young preschool children.This study investigated the level of impairment related to symptoms of ADHD in different functional domains. It also addressed how impairment caused by ADHD was related to ADHD subtype, symptom load, gender, and the co-occurrence of oppositional defiant disorder, conduct disorder, or both.Participating children (N = 807) who were 3.5 years old

Bothild Bendiksen, Heidi Aase, Elisabeth Svensson, Svein Friis, Anne Margrethe Myhre, Ted Reichborn-Kjennerud, Pål Zeiner

Scandinavian Journal of Child and Adolescent Psychiatry and Psychology, Volume 2 , ISSUE 3, 95–105

Research Article | 30-November-2013

A multicenter, randomized, controlled study of Training Executive, Attention, and Motor Skills (TEAMS) in Danish preschool children with attention-deficit/hyperactivity disorder: Rationale and description of the intervention and study protocol

Attention-deficit/hyperactivity disorder (ADHD) is a highly prevalent neurodevelopmental disorder that is often detected during the preschool years. Neuroimaging data indicate that children with ADHD have brains that are characterized by growth and functional anomalies. Data suggest that the diminution of ADHD symptoms is correlated with improved neural functioning and growth. On the basis of these findings, interventions that target neural growth, which indicates neural development, can

Helle Annette Vibholm, Jesper Pedersen, Anne Holm, Søren Krue

Scandinavian Journal of Child and Adolescent Psychiatry and Psychology, Volume 2 , ISSUE 1, 2–10

Research Article | 30-November-2013

Attention-Deficit/Hyperactivity Disorder, Autistic Traits, and Substance Use Among Missouri Adolescents

Although existing literature demonstrates the association of attention-deficit/hyperactivity disorder (ADHD) with both substance use (SU) and autism spectrum disorder (ASD), few studies have examined rates of SU among adolescents with elevated ASD symptoms, with or without comorbid ADHD. Clinic-based studies suggest a possible protective effect of ASD against SU, but this has not been confirmed in population-based studies.We examined alcohol, tobacco, and drug use in adolescents with either

Richard C. Mulligan, Angela M. Reiersen, Alexandre A. Todorov

Scandinavian Journal of Child and Adolescent Psychiatry and Psychology, Volume 2 , ISSUE 2, 86–92

Research Article | 30-November-2014

Nonverbal Reasoning in Preschool Children: Investigating the Putative Risk of Secondhand Smoke Exposure and Attention-Deficit/Hyperactivity Disorder as a Mediator

Exposure to secondhand smoke (SHS) has been found to be associated with cognitive deficits in children. However, relatively little is known about the relationship between SHS exposure, cognitive deficits, and smoking-related psychopathology, specifically attention-deficit/hyperactivity disorder (ADHD) and externalizing disorders such as conduct disorder (CD) and oppositional defiant disorder (ODD) in preschool children.Children (n = 54) between the ages of 4 and 6 years from a comprehensive

Duneesha De Alwis, Mini Tandon, Rebecca Tillman, Joan Luby

Scandinavian Journal of Child and Adolescent Psychiatry and Psychology, Volume 3 , ISSUE 2, 115–125

Research Article | 30-November-2012

How Prevalent Are Autistic Traits Among Children With Attention-Deficit/Hyperactivity Disorder? A Qualitative Review of the Literature

Twin, family, and linkage studies have indicated that attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorders (ASDs) share a portion of their heritable etiology. This suggests that individuals with ADHD may manifest different forms of ASDs that may range from fully developed syndromic forms of the disorder to milder manifestations of ASD symptomatology, which will henceforth be referred to as autistic traits.The main purpose of this study was to conduct a literature search

Mai Uchida, Stephen V. Faraone, Gagan Joshi, Andrea Spencer, Tara Kenworthy, K. Yvonne Woodworth, Joseph Biederman

Scandinavian Journal of Child and Adolescent Psychiatry and Psychology, Volume 1 , ISSUE 1, 33–40

Review | 04-May-2018

Developmental neurotoxicants and the vulnerable male brain: a systematic review of suspected neurotoxicants that disproportionally affect males

The prevalence of neurodevelopmental disorders (NDs), including autism spectrum disorder, attention-deficit/hyperactivity disorder, tic disorder, obsessive-compulsive disorder, and emotional disturbances, has increased notably in the past few decades. To date, debate continues as to the origins of NDs. Increases in widespread exposure to and bioaccumulation of chemical neurotoxicants have paralleled the upsurge in NDs, and are suggested to be causal agents for NDs. One consistent aspect of NDs

Janet K. Kern, David A. Geier, Kristin G. Homme, Paul G. King, Geir Bjørklund, Salvatore Chirumbolo, Mark R. Geier

Acta Neurobiologiae Experimentalis, Volume 77 , ISSUE 4, 269–296

research-article | 30-January-2020

What children and young people learn about ADHD from youth information books: A text analysis of nine books on ADHD available in Dutch

Introduction Attention-deficit/hyperactivity disorder (ADHD) is defined by the 5th edition of the Diagnostic and Statistical Manual as developmentally inappropriate inattention and impulsivity with or without hyperactivity (1). In the US 2.2 million school-age children, aged 6-11 (amounting to 8.9 percent of this age group) have a current diagnosis of ADHD. Two-thirds of these children are prescribed medication (2). In the Netherlands, it is unknown how many children are diagnosed with ADHD

Laura Batstra, Linda Foget, Caroline van Haeringen, Sanne te Meerman, Ernst Daniël Thoutenhoofd

Scandinavian Journal of Child and Adolescent Psychiatry and Psychology, Volume 8 , 1–9

Case report | 18-October-2018

Widespread cortical PET abnormalities in an adolescent related to a PNES dissociative state, PTSD, ADHD, and domestic violence exposure

Background:Accumulated evidence indicates that exposure to trauma is associated with the development of cognitive impairments and psychiatric symptoms in children and adolescents.Objective:In this case study of a female adolescent of 17 years, we aimed to evaluate how cortical positron emission tomography (PET) abnormalities relate to psychogenic non-epileptic seizure (PNES) dissociative state, post-traumatic stress disorder (PTSD), attention-deficit/hyperactivity disorder (ADHD), and domestic

Dejan Stevanovic, Leposava Brajkovic, Madhur Kumar Srivastava, Ivan Krgovic, Jasna Jancic

Scandinavian Journal of Child and Adolescent Psychiatry and Psychology, Volume 6 , ISSUE 2, 98–106

Research Article | 30-November-2012

Exploration of ADHD Subtype Definitions and Co-Occurring Psychopathology in a Missouri Population-Based Large Sibship Sample

There is some debate regarding the utility of Attention-Deficit/Hyperactivity Disorder (ADHD) subtypes as currently defined. Differences in co-occurring psychopathology among subtypes would support the validity of subtype definitions. To explore how ADHD subtype relates to co-occurring psychopathology in a large population-based sample of children and adolescents (n=5744). Parents completed the Strengths and Weaknesses of ADHD-symptoms and Normal behavior (SWAN) questionnaire, the Child

Angela M. Reiersen, Alexandre A. Todorov

Scandinavian Journal of Child and Adolescent Psychiatry and Psychology, Volume 1 , ISSUE 1, 3–13

Research Article | 18-October-2018

Validity of the Brief Child and Family Phone Interview by comparison with Longitudinal Expert All Data diagnoses in outpatients

). LEAD diagnoses were subsequently determined by two senior clinicians based on 1.2 years of clinical records including the K-SADS-PL and ensuing information from further assessments, psychological tests, information from teachers and other informants as well as treatment outcome. The Diagnostic and Statistical Manual of Mental Disorders subscales from the CBCL and the subscales from the BCFPI were compared with LEAD diagnoses. These measured symptoms of attention-deficit hyperactivity disorder

Markus Andersson, Martin Bäckström, Tord Ivarsson, Maria Råstam, Håkan Jarbin

Scandinavian Journal of Child and Adolescent Psychiatry and Psychology, Volume 6 , ISSUE 2, 83–90

research-article | 23-April-2021

Effectiveness and safety of dexamphetamine sulfate (Attentin®) in the routine treatment of children and adolescents with ADHD: results from a 12-month non-interventional study

Introduction Attention-deficit/hyperactivity disorder (ADHD) is one of the most common neurodevelopmental disorders of childhood, with an estimated worldwide prevalence of 7.2% in children ≤18 years (1). According to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5), ADHD is characterized by the core symptoms of inattention, hyperactivity and impulsivity that negatively impact social and academic/occupational functioning (2). The International Statistical

Henrik Uebel-von Sandersleben, Oliver Dangel, Roland Fischer, Michaela Ruhmann, Michael Huss

Scandinavian Journal of Child and Adolescent Psychiatry and Psychology, Volume 9 , 73–86

Research Article | 23-January-2019

Psychiatric problems and quality of life in a clinical sample of adolescents: The role of peer relations

disorders, QoL, and quality of peer relations were measured by self-report questionnaires.Results:Adolescents diagnosed with anxiety/depressive disorder reported more peer problems and lower QoL than adolescents with attention deficit/hyperactivity disorder. These findings were supported with symptom ratings. A path model with bootstrapping was used to assess the potential mediating role of peer problems in the association between symptoms and QoL, showing that peer problems partly mediated the

Ingunn Ranøyen, Eva Gulliksrud, Marit S. Indredavik, Frode Stenseng

Scandinavian Journal of Child and Adolescent Psychiatry and Psychology, Volume 6 , ISSUE 4, 183–192

Research paper | 04-May-2018

Antimuscarinic-induced convulsions in fasted mice after food intake: no evidence of spontaneous seizures, behavioral changes or neuronal damage

Prolonged or repeated seizures have been shown to cause spontaneous recurrent seizures, increased anxiety-related behavior, locomotor hyperactivity, impaired functions of learning and memory, and neuronal damage in the hippocampus and other brain regions in animals. Mice and rats treated with antimuscarinic drugs after fasting for two days or less develop convulsions after being allowed to eat ad libitum. To address whether such behavioral and neuroanatomic changes occur following these

Nurhan Enginar, Asiye Nurten, Aslı Zengin Türkmen, Gül İpek Gündoğan, Zeynep Güneş Özünal

Acta Neurobiologiae Experimentalis, Volume 77 , ISSUE 4, 373–381

Research Article | 30-November-2013

How do Girls with Low Functioning Autism Compare to Boys with Autism and Typically Developing Girls with regard to Behavior, Cognition, and Psychopathology?

developing girls. There were some weak trends for boys with ASD to show more compulsive behavior, inattention/hyperactivity and taste sensory overresponsivity than girls with ASD, but differences were not significant after controlling for multiple comparisons. The Block Design task, assessing attention to detail, showed a significant sex difference, with boys with ASD outperforming both girls with ASD and typically developing girls.Predominantly low functioning girls with ASD differed from typically

Camilla Nguyen, Angelica Ronald

Scandinavian Journal of Child and Adolescent Psychiatry and Psychology, Volume 2 , ISSUE 2, 55–65

Research paper | 06-February-2018

Effect of combined administration of aripiprazole and fluoxetine on cognitive functions in female rats exposed to ethyl alcohol

Alcoholism is a chronic and recurrent disease. The studies on ethyl alcohol show a progressive deterioration of cognitive functions (motor hyperactivity, operating memory). The aim of the study was to establish whether combined single and chronic administration of aripiprazole (ARI) and fluoxetine (FLU) affects animal locomotor activity or modifies spatial memory functions in female rats exposed to ethyl alcohol. Female Wistar rats were studied in the Morris Water Maze (MWM) and locomotor

Krzysztof Kus, Piotr Ratajczak, Natasza Czaja, Tomasz Zaprutko, Elżbieta Nowakowska

Acta Neurobiologiae Experimentalis, Volume 77 , ISSUE 1, 86–93

book-review | 19-August-2019

Validation of the Diagnostic Infant and Preschool Assessment in a Danish, trauma-exposed sample of young children

reliability for PTSD was fair (kappa = 0.42) and kappa values for scales of other disorders of MDD, attention-deficit/hyperactivity-disorder (ADHD) in-attentive subtype, ADHD-hyperactive/impulsive subtype, ODD, SAD, generalized anxiety disorder (GAD), and obsessive-compulsive disorder (OCD) ranged between 0.38 and 0.66. Test-retest intraclass correlation (ICC) ranged from 0.24 to 0.87 with a mean test-retest ICC of 0.61 and median test-retest ICC of 0.69. Concurrent criterion validity showed good

Sille Schandorph Løkkegaard, Mette Elmose, Ask Elklit

Scandinavian Journal of Child and Adolescent Psychiatry and Psychology, Volume 7 , 39–51

research-article | 30-November-2019

Decreased serotonin content and release in the ventral hippocampus of prenatally stressed male rats in response to forced swim test

prenatally stressed offspring in animal models is the low capacity to coping with stress due to the de-regulation of the HPA axis, thus increasing susceptibility to adult disorders, such as hyperactivity and hyperreactivity of HPA axis (Fan et al., 2009), metabolic diseases (Tamashiro et al., 2009), cognitive deficits (Guerrero et al., 2016), anxiety-like behavior (Brunton and Russel, 2010) or depressive-like behavior (Brunton, 2013). The ventral hippocampus is related to the stress response (Herman et

Felipe de Jesús Jiménez Vásquez, Diana Méndez Guerrero, Moisés Rubio Osornio, María del Carmen Rubio Osornio, Sandra Orozco Suárez, Socorro Retana-Márquez

Acta Neurobiologiae Experimentalis, Volume 80 , ISSUE 4, 331–343

Research Article | 30-November-2014

The Influence of Mental Health, Psychosocial Factors, and Educational Skills on the Educational Aspirations of Indigenous Sámi and Non-Indigenous Adolescents in the Arctic

%), 50.1% were female, and 10% were indigenous Sámi.Results:Educational skills as measured by higher average mark were associated with higher aspirations; lower average mark was associated with lower aspirations. Weaker peer support and stronger parental involvement influenced aspirations in individuals with both higher and lower aspirations. Adolescents with lower rates of hyperactivity and inattention problems reported higher aspirations, whereas adolescents with emotional problems showed a greater

Elisabeth Valmyr Bania, Christian Eckhoff, Siv Kvernmo

Scandinavian Journal of Child and Adolescent Psychiatry and Psychology, Volume 3 , ISSUE 3, 169–179

research-article | 25-March-2021

“Less stress”: a pilot study on a cognitive behavioral treatment program for anxiety in children with autism spectrum disorders

Introduction Autism spectrum disorders (ASD) are characterized by early-onset core difficulties in social- and communication skills and unusually restricted, repetitive behavior and interests with an estimated worldwide population prevalence of about 1%, affecting more males than females (1). Most children with ASD have one or more comorbid conditions like attention-deficit/hyperactivity disorder (ADHD), oppositional defiant disorder (ODD), anxiety- and mood disorders, implying a further

Beate Oerbeck, Kristin Romvig Overgaard, Tony Attwood, Jon Fauskanger Bjaastad

Scandinavian Journal of Child and Adolescent Psychiatry and Psychology, Volume 9 , 30–40

Clinical Practice | 22-December-2016

Toward a new generation of quality registries for neurodevelopmental disorders: the example of NEUROPSYK

, attention-deficit/hyperactivity disorder, intellectual disabilities, communication disorders, specific learning disorders, and motor disorders. Medication and behavioral interventions are recorded and patient outcomes over time are measured with the economical and user-friendly Clinical Global Impression tool, the Global Assessment of Functioning instrument, and patient-reported health-related quality of life.NEUROPSYK minimizes administrative work for health care professionals because it is integrated

Anna Löfgren Wilteus, Frida Bartonek, Jacqueline Borg, Sven Bölte

Scandinavian Journal of Child and Adolescent Psychiatry and Psychology, Volume 4 , ISSUE 3, 141–146

research-article | 06-June-2019

Further evidence of the Diagnostic Utility of the Child Behavior Checklist for identifying pediatric Bipolar I Disorder

1.8 ± 1.0 1.7 ± 0.9 1.8 ± 1.1 z = -1.29 0.20 n (%) n (%) n (%) n (%) n (%) n (%) n (%) n (%) n (%) n (%) Male 238 (100) 13 (100) 0 (0) 0 (0) 48 (59) 43 (67) n/a 34 (77) 286 (54) 90 (69) χ2 = 10.06 0.002 Caucasianb 238 (100) 13 (100) 192 (93) 9 (100) 58 (76) 62 (98)* n/a 38 (86) 488 (94) 122 (95) χ2 = 0.10 0.76 Note. ADHD = attention deficit hyperactivity disorder; BP = Bipolar aSocioeconomic status (SES) was measured using the 5-point Hollingshead scale. A higher

Amy Yule, Maura Fitzgerald, Timothy Wilens, Janet Wozniak, K. Yvonne Woodworth, Alexa Pulli, Mai Uchida, Stephen V. Faraone, Joseph Biederman

Scandinavian Journal of Child and Adolescent Psychiatry and Psychology , Volume 7 , 1–8

Research Article | 05-July-2017

Child self-report and parent ratings for the Strengths and Difficulties Questionnaire: Norms and agreement in a Swedish random population sample

higher ratings for boys on hyperactivity and total difficulties and for girls on emotional symptoms. However, findings on increased difficulties with age concurred with prior studies. Research on children’s mental health should be widely and systematically conducted at regular intervals and encompasses large, representative samples in order to inform national public health and health-care policy regarding measures to support children and enhance their mental health.

Bojing Liu, Karin Engström, Isabel Jadbäck, Sara Ullman, Anne H. Berman

Scandinavian Journal of Child and Adolescent Psychiatry and Psychology, Volume 5 , ISSUE 1, 13–27

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