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Research paper

The effect of network template from normal subjects in the detection of network impairment

Chun‑Chao Huang, Shang‑Hua Lin, Ching‑Po Lin, The Alzheimer’s Disease Neuroimaging Initiative

Acta Neurobiologiae Experimentalis , ISSUE 4, 294–303

Review Paper

Antiepileptic drugs as a new therapeutic concept for the prevention of cognitive impairment and Alzheimer’s disease. Recent advances

Introduction. Excessive accumulation of amyloid-beta (A_) peptides in the brain results initially in mild cognitive impairment (MCI) and finally in Alzheimer’s disease (AD). Evidences from experimental and clinical studies show that pathological hyperexcitability of hippocampal neurons is a very early functional impairment observed in progressive memory dysfunctions. Therefore, antiepileptic drugs (AEDs) whose mechanism of action is aimed at inhibition of such neuronal hyperexcitability

Krzysztof Sendrowski, Wojciech Sobaniec

Journal of Epileptology , ISSUE 2, 139–147

Original Paper

Handedness, cognitive processing and intelligence in patients with epilepsy

) with epilepsy participated in the study. Patients were divided into two groups. The first group included 112 patients that were characterized by intelligence and cognitive impairment while the second group (20 patients) had no mental deterioration and was regarded as controls. The two diagnostic categories accorded with ICD-10 criteria. The diagnosis of Dementia (F-02.8) was confirmed in 54 patients, while the diagnosis of Mild Cognitive Impairment (F-06.7) was confirmed in 58 patients. Results

Vladimir V. Kalinin, Daniya M. Nazmetdinova, Alexander V. Basamygin

Journal of Epileptology , ISSUE 1, 5–10

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