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Article | 09-November-2020

A maternal warm-reactive autoantibody presenting as a positive direct antiglobulin test in a neonate

Autoimmune hemolytic anemia in pregnancy is a rare cause of hemolytic disease of the newborn. This report describes a neonate with a mild hemolytic process and a positive direct antiglobulin test (DAT) presenting as the first manifestations of a maternal warm-reactive autoantibody. A full-term male neonate, blood group O, had a strongly positive DAT and laboratory evidence suggestive of a mild hemolytic process. The neonate’s mother was also group O and had a negative antibody screen

Terry D. Williamson, Linda H. Liles, Douglas P. Blackall

Immunohematology, Volume 13 , ISSUE 1, 6–8

Review | 14-December-2020

A review: controversies in blood component use in newborns

Advances in the care of the critically ill neonate have necessitated dramatic changes in the blood bank's response, especially to the needs of the low-weight premature infant. The neonate is now considered a major consumer of blood products, and the packaging and administration of these products must he altered to suit its specialized needs. The indications and preparations for small-volume red blood cell (RBC) transfusions are of particular concern. Small volume RBC transfusions are both

Naomi L.C. Luban

Immunohematology, Volume 7 , ISSUE 1, 1–7

Research Article | 29-June-2016

Usefulness of ultrasound examination in the evaluation of a neonate's body fluid status

Joanna Kieliszczyk, Wojciech Baranowski, Wojciech Kosiak

Journal of Ultrasonography, Volume 16 , ISSUE 65, 125–134

Case report | 13-September-2016

Adrenal abscess in a 3-week-old neonate – a case report

Małgorzata Rumińska, Ewelina Witkowska-Sędek, Stanisław Warchoł, Teresa Dudek-Warchoł, Michał Brzewski, Beata Pyrżak

Journal of Ultrasonography, Volume 15 , ISSUE 63, 429–437

Article | 17-February-2021

K antigens on neonatal red blood cells blocked by anti-K with titer of 32

autoantibody, but it destroys K antigen expression. CPD is not always effective in eluting the antibody.9,10 Molecular genotyping is not always available, and it is not as fast as the other methods. So far, there have been four case reports that describe false-negative K phenotyping due to blocking by maternal anti-K.10–13 We present a case report of a potent anti-K with a titer of 32 that caused this blocking phenomenon. Case Report A 29-year-old mother (G5P3A2) delivered a term male neonate by emergency

J. Novoselac, M. Raos, G. Tomac, M. Lukić, B. Golubić Ćepulić

Immunohematology, Volume 36 , ISSUE 2, 54–57

research-article | 15-June-2020

Gradual diagnosis and clinical importance of prenatally detected persistent left superior vena cava with absent right superior vena cava – a case report and literature review

tertiary center of prenatal cardiology should not only detect fetal heart abnormalities, but also offer information about treatment options, prognosis, and counsel about the way and place of delivery, as well as about future procreative plans. Moreover, many experienced clinics may provide care for a neonate, an infant and a child if necessary. We recommend neonatal echocardiographic examination after birth and at the age of 3 and 12 months for possible CoA detection. Fortunately, in our case, the

Oskar Sylwestrzak, Maria Respondek-Liberska

Journal of Ultrasonography, Volume 20 , ISSUE 81, e146–e150

Review | 06-December-2020

Review: red cell alloantibody formation in the neonate and infant: considerations for current immunohematologic practice

Louis DePalma

Immunohematology, Volume 8 , ISSUE 2, 33–37

Article | 18-October-2020

Significant ABO hemolytic disease of the newborn in a group B infant with a group A2 mother

ABO hemolytic disease of the newborn (HDN) occurs almost exclusively in infants of blood group A or B who are born to group O mothers because IgG anti-A or -B occurs more commonly in group O than in group A or B individuals. We report a case in which clinically significant ABO-HDN occurred in a group B neonate from anti-B of a group A2 mother. The IgG anti-B titer was much higher (256) than that found in a group A1 mother/infant control group (≤ 32). The maternal antibody screen was negative

Hye-Ran Jeon, Beverly E.W. Calhoun, Mohammad Pothiawala, Marguerite Herschel, Beverly W. Baron

Immunohematology, Volume 16 , ISSUE 3, 105–108

Case report | 09-October-2019

Postpartum acute hemolytic transfusion reactions associated with anti-Lea in two pregnancies complicated by preeclampsia

, red blood cell units, compatible by electronic crossmatch, were issued and transfused. The subsequent transfusion reactions were characterized by acute intravascular hemolysis, evidenced by both clinical and laboratory criteria. These two cases demonstrate that, even when least anticipated, hemolytic transfusion reactions may occur. As expected, neither live-born neonate was affected by hemolytic disease of the fetus and newborn. Because both transfusion reactions occurred in non–group O

Marcia Marchese

Immunohematology, Volume 33 , ISSUE 3, 114–118

Case report | 26-October-2019

Blocked D phenomenon and relevance of maternal  serologic testing

elution and gentle heat elution (at 56°C) confirmed the presence of anti-D on neonatal RBCs. The baby received two exchange transfusions with group O, D–, packed RBCs compatible with his own serum. Later, on day 3, the neonate’s mother was typed as group AB, D–, and her serum revealed the presence of alloanti-D, -C, and -S reactive in the anti-human globulin phase. The anti-D titer was 1024. This report highlights the “blocking” phenomenon caused by maternal anti-D in

Ashish Jain, Vijay Kumawat, Neelam Marwaha

Immunohematology, Volume 31 , ISSUE 3, 116–118

Case report | 16-October-2019

Management of pregnancy sensitized with anti-Inb with monocyte monolayer assay and maternal blood donation

local and national query revealed that no appropriate units of RBCs were available for either the mother or neonate. Given this information, serial maternal autologous blood donations were performed, and a comprehensive care plan with a multidisciplinary approach for delivery, neonatal management, and preparation for hemorrhage was developed. Published data and our experience suggest that maternal blood donation appears to be a safe and effective way to manage mothers who cannot safely use the

Raj Shree, Kimberly K. Ma, Lay See Er, Meghan Delaney

Immunohematology, Volume 34 , ISSUE 1, 7–10

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