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Review

c-Fos and neuronal plasticity: the aftermath of Kaczmarek’s theory

The development of molecular biology methods in the early 1980s led to a better understanding of the role of transcription factors in mammalian cells. The discovery that some transcription factors are critically important for cells to switch between different functional states was fundamental for modern molecular neurobiology. In the 1980s Leszek Kaczmarek proposed that, analogically to the cell cycle or to cell differentiation, long-term synaptic plasticity, learning, and memory should also

Jacek Jaworski, Katarzyna Kalita, Ewelina Knapska

Acta Neurobiologiae Experimentalis , ISSUE 4, 287–296

research-article

Isolation and characterization of human amniotic fluid and SH-SY5Y/BE(2)-M17 cell derived exosomes

(Andres et al., 2013; Ross et al., 2015), which are two well-known neuronal models, to explore characteristics of their exosomes and to further understand and explore neurodifferentiation and neurobiology. In addition, we used different sources to compare yield and purity of various exosome isolation methods. METHODS Cell culture and sample collection SH-SY5Y and BE(2)-M17 are human neuroblastoma cell lines that are commonly used for modelling neurodegenerative diseases, and for studying basic

Nayer Seyfizadeh, Narges Seyfizadeh, Reza Rahbarghazi, Alireza Nourazarian, Sajed Borzouisileh, Abdolhakim Palideh, Farideh Elahimanesh, Hamed Hamishehkar, Leyla Salimi, Mohammad Nouri, Maryam Abtin

Acta Neurobiologiae Experimentalis , ISSUE 3, 262–270

Review

Neurobiological Findings in Youth with Borderline Personality Disorder

Romuald Brunner, Romy Henze, Julia Richter, Michael Kaess

Scandinavian Journal of Child and Adolescent Psychiatry and Psychology , ISSUE 1, 22–30

Research paper

Acute cold allodynia induced by oxaliplatin is attenuated by amitriptyline

Oxaliplatin is a third-generation, platinum-based antitumor drug used to treat colorectal cancer. Since its main adverse effect is neuropathic pain resulting from chemotherapy-induced peripheral neuropathy (CIPN), this drug is used to study the neurobiology of CIPN in rodents and to search for analgesics that could attenuate neuropathic pain symptoms – cold and tactile allodynia that develop in most of the oxaliplatin-treated subjects. In this research, testing across various temperatures, we

Anna Furgała, Robert Sałat, Kinga Sałat

Acta Neurobiologiae Experimentalis , ISSUE 4, 315–321

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