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Acta Neurobiologiae Experimentalis

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Diazepam and electrical stimulation of paleocerebellar cortex inhibits seizures in pentylenetetrazol-kindled rats

modulatory action by ES of paleocerebellum on kindling-induced seizures. Stimulation was performed 18.0 min after the moment of kindled PTZ (30.0 mg/kg, i.p.) administration and 4.0 min after the moment of cessation of generalized ictal EEG discharge. The rat was treated with DIA (0.1 mg/kg, i.p.). The intensity of stimulation was 100.0 mcA. (C) Inhibition of kindling-induced seizures after ES of the paleocerebellar cortex. Stimulation was performed 20.0 min after the moment of kindled PTZ (30.0 mg/kg

Leonid S. Godlevsky, Oleksii O. Shandra, Mykhailo P. Pervak, Alexey A. Shandra

Acta Neurobiologiae Experimentalis, Volume 80 , ISSUE 3, 322–330