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Case report

Heterotopic pregnancy – how easily you can go wrong in diagnosing? A case study

Abstract Introduction: Heterotopic pregnancy is a rare, but potentially life-threatening pathology. The diagnosis of heterotopic pregnancy is still one of the biggest challenges in modern gynecology. The incidence of those pregnancies in natural conception is about 1:30000. Case presentation: We present an unusual case of a heterotopic pregnancy which was misdiagnosed in the first trimester as a dichorionic twin pregnancy. At 13 weeks of gestation, the patient presented with an acute abdomen

Michał Ciebiera, Aneta Słabuszewska-Jóźwiak, Kornelia Zaręba, Grzegorz Jakiel

Journal of Ultrasonography , ISSUE 75, 355–358

Review Article

Cesarean scar pregnancy – a new challenge for obstetricians

Diagnosis and treatment of ectopic cesarean scar pregnancy has become a challenge for contemporary obstetrics. With an increase in the number of pregnancies concluded with a cesarean section and with the development of transvaginal ultrasonography, the frequency of cesarean scar pregnancy diagnoses has increased as well. The aim of the study is to evaluate various diagnostic methods (ultrasonography in particular) and analyze effective treatment methods for cesarean scar pregnancy. An

Piotr Pędraszewski, Edyta Wlaźlak, Wojciech Panek, Grzegorz Surkont

Journal of Ultrasonography , ISSUE 72, 56–62

Review

The role of ultrasonography in methotrexate therapy for ectopic pregnancy

Medical management of ectopic pregnancy with methotrexate, an antimetabolite of folic acid, is an important alternative to surgical treatment, as it ensures a similar outcome whilst being far less invasive. Ultrasound evaluation does not only facilitate an accurate diagnosis, but also helps to select patients most likely to benefit from methotrexate treatment, as opposed to those with a high likelihood of failure of medical management, who are thus eligible for primary surgical treatment

Piotr Czuczwar

Journal of Ultrasonography , ISSUE 73, 158–161

research-article

Gallbladder diseases in pregnancy: Sonographic findings in an indigenous African population

Introduction During pregnancy, gallbladder disease is often due to gallstones and biliary sludge(1). Although gallbladder disease also occurs in men, a higher prevalence has been reported in women(2,3). Hossain et al.(4) reported that gall bladder diseases are four times more common in women than men. Likewise, Eze et al. reported a male-to-female ratio of 2.8:1 in the prevalence of these diseases(2). This gender predilection constitutes a risk during pregnancy, and it has been found that gall

Bukunmi Michael Idowu, Stephen Olaoluwa Onigbinde, Isaiah Uzezi Ebie, Michael Temidayo Adeyemi

Journal of Ultrasonography , ISSUE 79, 269–275

Research Article

Uterine artery Doppler velocimetry in hypertensive disorder of pregnancy in Nigeria

Aim of the studyTo evaluate the value of uterine artery Doppler indices and waveform pattern in predicting fetuses at risk for intrauterine growth restriction in hypertensive disorders of pregnancy.Materials and methodsThis was a prospective cross-sectional study including 80 pregnant subjects with hypertensive disorders of pregnancy and two control groups. Uterine artery Doppler sonography was performed in all study participants. Uterine artery Doppler indices across the groups were compared

Ibukun A. Abidoye, Oluwagbemiga O. Ayoola, Bukunmi M. Idowu, Adeniyi S. Aderibigbe, Olabisi M. Loto

Journal of Ultrasonography , ISSUE 71, 253–258

Case report

A twin pregnancy with a hydatidiform mole and a coexisting live fetus: prenatal diagnosis, treatment, and follow-up

Twin molar pregnancy with a hydatidiform mole and a coexisting live fetus is a rare form of gestational trophoblastic disease associated with an increased risk of obstetric complications and poor perinatal outcome. Prenatal diagnosis is essential for couple counseling and follow-up in Tertiary Reference Centers. Magnetic resonance imaging is important for the diagnostic differentiation of placental mesenchymal dysplasia and exclusion of myometrial invasion. Here we present a case of twin molar

Antonio Braga, Bruna Obeica, Heron Werner, Sue Yazaki Sun, Joffre Amim Júnior, Jorge Rezende Filho, Edward Araujo Júnior

Journal of Ultrasonography , ISSUE 71, 299–305

Review Article

Current knowledge on the use of ultrasound measurements of fetal soft tissues for the assessment of pregnancy development

Ultrasonography, with its detailed imaging of the fetus, is very widely used in obstetrics. The primary aim of ultrasound scanning in pregnancy is to limit the risk of obstetric complications by early detection of abnormalities, such as intrauterine growth restriction and macrosomia. Currently, morphometric formulae are used for estimating fetal weight. They utilize basic biometric parameters. However, Hadlock formula, used for fetal weight estimation, has an error rate of 20%. For this reason

Aleksandra Warska, Anna Maliszewska, Anna Wnuk, Beata Szyszka, Włodzimierz Sawicki, Krzysztof Cendrowski

Journal of Ultrasonography , ISSUE 72, 50–55

research-article

Dynamics of Social Networks Following Adolescent Pregnancy

Introduction Despite a downward trend in adolescent pregnancy since the 1990’s, pregnancy is still a relatively common occurrence among American teenagers. Approximately one in ten sexually active girls experience a pregnancy sometime during their teenage years – about 5% of adolescent females nationally (Guttmacher Institute, 2016). This prevalence makes the United States the leader in adolescent pregnancies amongst industrialized nations (Kearney & Levine, 2012). High incidence of teenage

Elizabeth Humberstone

Journal of Social Structure , ISSUE 1, 1–34

original-paper

Fertility outcome after saline sonography guided removal of intrauterine polyps in women with unexplained infertility

recommend saline infusion sonography or hysteroscopy as the initial infertility investigation. Their stance on the subject is derived from the fact that removal has not been proven worthwhile(7). Studies showing improved clinical pregnancy rates in women with unexplained infertility after removal of unsuspected polyps are being reported. Cochrane database review concluded that hysteroscopic removal of submucous fibroids in women suffering from otherwise unexplained infertility may be beneficial(8

Rubina Izhar, Samia Husain, Suhaima Tahir, Sonia Husain

Journal of Ultrasonography , ISSUE 77, 113–119

Short Report

Can pregnant women accurately report snoring? A pilot study

Sleep-Disordered Breathing (SDB) has been associated with possible negative outcomes, such as preeclampsia and foetal growth restriction. SDB screening tools have been developed for use within general populations. These included the use of self-reports and objective measurements. Seventeen pregnant women within their 34th to 37th week of pregnancy were recruited.  Participants undertook an overnight study within their home and SDB symptoms were monitored using the Watch-PAT 200 and an

Jane Warland, Jacinta Carpentieri, Jillian Dorrian

Eat, Sleep, Work , ISSUE 1, 57–64

Review

Ultrasound screening for pyelectasis in pregnant women. Clinical necessity or “art for art’s sake”?

Renal pelvicalyceal dilatation is caused by urine retention in the upper urinary tract. It is referred to as pyelectasis in medical literature. This term does not indicate the cause that leads to the dilatation of and urine retention in the renal pelvicalyceal system. Mild pelvicalyceal dilatation during pregnancy is usually considered to be physiological in nature – it can occur in up to 90% of pregnant women. Retention is more common in the right kidney, in primigravidae, in the second half

Piotr Szkodziak

Journal of Ultrasonography , ISSUE 73, 152–157

Research paper

Testosterone enhancement during pregnancy influences social coping and gene expression of oxytocin and vasopressin in the brain of adult rats

Steroid hormones are important mediators of prenatal maternal effects and play an important role in fetal programming. The aim of our study was to investigate how testosterone enhancement during pregnancy influences neurobehavioral aspects of social coping of rat offspring in adulthood. Pregnant rat dams were exposed to depot form of testosterone during the last third of pregnancy (i.e., beginning on the 14th day of pregnancy). Their adult offspring were later tested in a social interaction

Zuzana Dzirbíková, Alžbeta Talarovičová, Peter Štefánik, Lucia Olexová, Lucia Kršková

Acta Neurobiologiae Experimentalis , ISSUE 3, 264–270

case-report

Prenatal diagnosis of congenital megalourethra in the second trimester of pregnancy

keyhole sign (Fig. 2), dorsally curved penis with largely dilated penile urethra (18 × 5 mm) (Fig. 3). The amniotic fluid volume was normal. No other abnormalities were found. Based on such abnormal sonographic findings, including hydronephrosis, hydroureters, megacystis and dilated penile urethra, we came to a diagnosis of scaphoid congenital megalourethra. After parental counseling, termination of pregnancy proved the prenatal findings (Fig. 4). Fig. 1. A. Dilated right renal pelvis B. dilated

Do Duy Anh, Ha To Nguyen, Simon Meagher, Edward Araujo Júnior

Journal of Ultrasonography , ISSUE 79, 302–304

research-article

Cervical stenosis and pregnancy rate after ultrasound guided cervical dilation in women undergoing saline infusion sonography

frequently cited cause of decreased clinical pregnancy rates in in vitro fertilization (IVF) cycles(6). It has been suggested that trial transfers under ultrasound guidance improve conception rates. Saline infusion sonography involves the use of soft tip Foley’s catheter for the introduction of saline used for cavity distension and checking for free spill(7). Cervical dilation with a Hegar’s dilator may be needed prior to introduction of this Foley’s catheter in cases of stenosis. Since a stenosis that

Journal of Ultrasonography , ISSUE 81, e116–e121

Report

Laboratory management of perinatal patients with apparently “new” anti-D

Despite the existence of long-standing, well-organized programs for Rh immune globulin (RhIG) prophylaxis, immune anti-D continues to be detected in the D– perinatal population. Between 2006 and 2008, 91 prenatal patients, found to have a previously unidentified anti-D, were followed up with a survey to their treating physician and with additional serologic testing where possible. The physician survey requested pregnancy and RhIG history information, including recent or distant potential

Judith L. Hannon, Gwen Clarke

Immunohematology , ISSUE 3, 108–111

Case report

A LU:−16 individual with antibodies

Antibodies against Lutheran blood group antigens have been observed during first-time pregnancy. Samples from a woman of African descent were tested in our immunohematology laboratory on several occasions since 2001. Her samples were phenotyped as Lu(a+b−), and anti-Lub was suspected but not identified. She was asked to make autologous donations in preparation for her delivery, which she did. In 2010, two antibodies were identified: anti-Lea and -Lub. Six years later, a third

Carole Éthier, Cynthia Parent, Anne-Sophie Lemay, Nadia Baillargeon, Geneviève Laflamme, Josée Lavoie, Josée Perreault, Maryse St-Louis

Immunohematology , ISSUE 3, 110–113

Original Paper

High Seroprevalence of CMV Among Women of Childbearing Age Implicates High Burden of Congenital Cytomegalovirus Infection in Poland

Cytomegaloviruses are common worldwide, with variable frequency of infections. The infection in pregnancy may lead to pregnancy loss or serious sequelae for the child. To understand the risk posed by CMV in Poland we conducted cross-sectional study on women aged 15–49 basing on existing serum bank. Age dependent CMV incidence, the rates of congenital infection and sequelae were modelled from sero-prevalence, literature and demographic data. The overall anti-CMV IgG prevalence was 81.9

Joanna Siennicka, Milena Dunal-Szczepaniak, Agnieszka Trzcińska, Paulina Godzik, Magdalena Rosińska

Polish Journal of Microbiology , ISSUE 4, 425–432

Article

Anti-Vel alloimmunization and severe hemolytic disease of the fetus and newborn

therapy has been noted to date. We report such a case recently encountered at our Fetal Center. Case Report The patient was a 31-year-old woman (gravida/para/abortus [GPA] = G2P1000) who was referred to our Fetal Center from a neighboring state for evaluation of Vel alloimmunization. Her past history was significant, with the finding of a positive antibody detection test and identification of anti-Vel during her previous pregnancy. Based on literature reports of only mild-to-moderate HDFN in

K.J. Moise, Y. Morales, M.F. Bertholf, S.N. Rossmann, Y. Bai

Immunohematology , ISSUE 4, 152–154

Research Article

Conjoined twins – role of imaging and recent advances

case was further evaluated by MRI.ResultsThree cases of conjoined twins (cephalopagus, thoracopagus and omphalopagus) were accurately diagnosed on antenatal ultrasound. After detailed counseling of the parents and obtaining written consent, all the three cases of pregnancy were terminated. Delivery of the viable conjoined twins was achieved without any complications to the mothers, and all the three conjoined twins died after a few minutes.ConclusionUltrasound enables an early and accurate

Rishi Philip Mathew, Swati Francis, Ram Shenoy Basti, Hadihally B. Suresh, Annie Rajarathnam, Prema D. Cunha, Sujaya V. Rao

Journal of Ultrasonography , ISSUE 71, 259–266

Research Article

Nonverbal Reasoning in Preschool Children: Investigating the Putative Risk of Secondhand Smoke Exposure and Attention-Deficit/Hyperactivity Disorder as a Mediator

continued to be negatively associated with nonverbal reasoning skills after adjustment for maternal education, maternal smoking during pregnancy, and maternal reports of exposure to SHS during pregnancy in separate models.Children who grow up in an environment with adults who smoke are vulnerable to several social and environmental risk factors. The findings of this study suggest that exposure to SHS during early childhood should also be considered as a potential variable in the risk trajectory and as a

Duneesha De Alwis, Mini Tandon, Rebecca Tillman, Joan Luby

Scandinavian Journal of Child and Adolescent Psychiatry and Psychology , ISSUE 2, 115–125

Review

Can ultrasound be helpful in selecting optimal management methods for pregnancies complicated by placental non-trophpblastic tumors?

Placental chorioangioma is the most common subtype of non-trophoblastic placental tumors. Other subtypes are very rare and usually associated with an uneventful course of pregnancy. Most chorioangiomas are small and of no clinical significance. Giant chorioangiomas may be associated with serious fetal and maternal complications. So far, no established ultrasound guidelines are available for the management of placental non-trophoblastic tumors. This may be attributed to the rarity of the disease

Nabil Abdalla, Robert Piórkowski, Paweł Stanirowski, Monika Pazura, Krzysztof Cendrowski, Włodzimierz Sawicki

Journal of Ultrasonography , ISSUE 69, 116–122

Original Paper

Antenatal corticosteroid treatment for the prevention of peri-intraventricular haemorrhage in preterm newborns: a retrospective cohort study using transfontanelle ultrasonography

cycle per week. The diagnosis of periintraventricular haemorrhage was based on transfontanelle ultrasonography, using the Papile’s classification. The following risk factors for peri-intraventricular haemorrhage were assessed: birth weight, gestational age at delivery, type of delivery, newborn’s sex, surfactant administration, premature rupture of membranes and previous history of infection during the current pregnancy. The student’s t-test and chi-square test were used for

Bianca A. Almeida, Livia T. Rios, Edward Araujo Júnior, Luciano M. Nardozza, Antonio F. Moron, Marília G. Martins

Journal of Ultrasonography , ISSUE 69, 91–95

research-article

Comparison of the resistive indices obtained in the uterine artery and the ophthalmic artery in preeclamptic and normotensive patients in Doppler US

Introduction Preeclampsia is one of the leading causes of maternal morbidity throughout the world(1). It is a pregnancy disorder characterized by high blood pressure and often a significant amount of protein in urine(2). The incidence of preeclampsia is from 5–10%(3,4), and its prevalence is 2–8%(5). The possible causes of preeclampsia include: an exaggerated inflammatory response by endothelial cells, which intrinsically increases the local blood supply to the affected area,(6) and the

Syeda Rabi Madina, Raham Bacha, Syed Amir Gilani, Wafa Fatima, Wahida Awais, Hamnah Fatima, Iqra Manzoor

Journal of Ultrasonography , ISSUE 81, e95–e99

Original Paper

Modeling alloantibody formation to highincidence red blood cell antigens in immune responders using genotypic data  

;, Immucor, Warren, NJ) was performed on all patient specimens referred for molecular testing over 45 months; serologic and clinical data were analyzed. We used simple and multiple logistic regression to model the risk factors for alloimmunization to an HIA. Of the 2591 patients genotyped, 32 (1.2%) were homozygous for at least one variant predicting absence of an HIA. Of these 32 patients, prior transfusion or pregnancy history was available for 29 (91%). Four susceptible patients made an antibody to an

Patricia A.R. Brunker, Keerthana Ravindran, R. Sue Shirey

Immunohematology , ISSUE 1, 9–14

Case report

Fetal ultrasound: Early diagnosis and natural evolution of proximal femoral focal deficiency

Proximal femoral focal deficiency is an extremely rare congenital anomaly with only a few case reports in the literature. This case illustrates one diagnosed by prenatal ultrasound. The diagnosis may be isolated or associated with other abnormalities and syndromes. This report describes the early obstetrical ultrasound diagnosis, its evolution and associated findings throughout pregnancy. To the best of our knowledge, it is the first report associating this diagnosis with sickle cell trait

Eugenio O. Gerscovich, Simran Sekhon, Thomas W. Loehfelm, Adam Greenspan

Journal of Ultrasonography , ISSUE 71, 294–298

Review

Ultrasonographic criteria of cesarean scar defect evaluation

. Ultrasound evaluation of the cesarean section scar is an important element of obstetric and gynecologic practice, especially in the case of further pregnancies. It facilitates an early diagnosis of a cesarean scar ectopic pregnancy, and the prediction of the risk for perinatal dehiscence in the case of a vaginal birth after a cesarean section.

Andrzej Woźniak, Krzysztof Pyra, Hugo Rio Tinto, Sławomir Woźniak

Journal of Ultrasonography , ISSUE 73, 162–165

research-article

Color Doppler ultrasound of spiral artery blood flow in mid first trimester (4–8 weeks) in cases of threatened abortion and in normal pregnancies

Introduction Threatened miscarriage is a clinical term for vaginal bleeding that occurs during the first 20 weeks of pregnancy where fetus is clinically supposed to be alive. This bleeding may or may not be associated with abdominal pain. About 1/5 of all pregnant females present with symptoms of threatened abortion in the first trimester and almost half of the women with threatened abortion result in pregnancy loss(1). Even women with threatened abortion and a living embryo have increased

Rohit Bhoil, Sushruti Kaushal, Reena Sharma, Jaswinder Kaur, Tanupriya Sharma, Rohini Thakur, Rakesh Sharma

Journal of Ultrasonography , ISSUE 79, 255–260

Editorial

Intrapartum sonography – eccentricity or necessity?

Ultrasonography has been extensively used in obstetrics and gynecology since 1980’s.It found application in pediatric gynecology, procreation period, post-menopause, pregnancy monitoring and after delivery. Although the fi rst reports on the use of ultrasonography in assessing delivery mechanism were published in 1990’s, yet to date labor progress is evaluated by means of physical examination in most delivery units. Intrapartum sonography is not routinely performed despite the fact that

Marzena Dębska, Piotr Kretowicz, Romuald Dębski

Journal of Ultrasonography , ISSUE 61, 125–136

research-article

Long-term offspring epilepsy outcomes following planned assisted homebirth versus hospital birth

, the data on the course of pregnancy and delivery were re-evaluated for abnormalities and subsequent risks. Definitions Planned homebirth was defined as planned birth at home guided by a registered midwife. Hospital births included public tertiary care or secondary care hospitals, other obstetric units led by trained obstetrician or, in fewer cases, primary care (municipal) hospitals led by general practitioner. The general practitioners of primary care hospitals were by rule experienced

Matti Sillanpää, Maiju M. Saarinen, Päivi Polo-Kantola

Journal of Epileptology , ISSUE 1-2, 7–14

Case report

Two cases of the variant RHD*DAU5 allele associated with maternal alloanti-D  

Rh is a complex blood group system with diverse genotypes that may encode weak and partial D variants. Standard serologic analysis may identify clinically significant D variants as D+; nevertheless, individuals with these D variants should be managed as D– patients to prevent antibody formation to absent D epitopes. Variant identification is necessary during pregnancy to allow for timely and appropriate Rh immune globulin (RhIG) prophylaxis for hemolytic disease of the fetus and newborn

Jennifer A. Duncan, Susan Nahirniak, Rodrigo Onell, Gwen Clarke

Immunohematology , ISSUE 2, 60–63

research article

One-year follow-up of The Incredible Years Parents and Babies Program: A pilot randomized controlled trial

Introduction The foundation of a healthy life begins in pregnancy and early adversity can have detrimental long-term consequences for affected children (1–4). This knowledge has led to increased investment in supporting early childhood development through interventions such as parenting programs (5). Infants remain dependent upon their parents for many years after birth and are at risk of developmental harm if they suffer neglect or maltreatment during this time because brain plasticity is at

Maiken Pontoppidan, Tróndur Møller Sandoy, Sihu K. Klest

Scandinavian Journal of Child and Adolescent Psychiatry and Psychology , 123–134

Case report

Clinical report: a rare co-occurrence of tuberous sclerosis complex and Rett syndrome in a girl with mental retardation, epilepsy and autism

delivery after a non-complicated pregnancy. Family history was negative for epilepsy and mental retardation. The neonatal period was uneventful and psychomotor development was normal before the child became 1.5 years old. At the age of 18 months the girl developed hand-wringing stereotypes, facial hypotonia, ataxia and gait apraxia. She lost eye-to-eye contact and verbal contact with relatives, and became indifferent to the surrounding environment. When she was 2 years old, focal adversive seizures

Elena Belousova, Vladimir Sukhorukov, Marina Dorofeeva, Lev Shagam, Dmitrii V. Vlodavetz

Journal of Epileptology , ISSUE 1-2, 47–51

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