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Article

THE STRINGENT RESPONSE AND ITS INVOLVEMENT IN THE REACTIONS OF BACTERIAL CELLS TO STRESS

, autoinducers stimulate the processes leading to a change in the expression of genes that enable the synchronization of bacteria’s metabolism. The process of communication between bacteria, in which the bacteria take advantage of the production and detection of autoinducers in order to monitor the density of the population is called quorum sensing. This phenomenon is important with respect to controlling processes such as biofilm formation, secretion of virulence factors, bioluminescence, production of

Julia Berdychowska, Justyna Boniecka, Grażyna B. Dąbrowska

Postępy Mikrobiologii - Advancements of Microbiology , ISSUE 2, 127–142

Original Paper

Deletion of atoR from Streptococcus pyogenes Results in Hypervirulence in a Mouse Model of Sepsis and is LuxS Independent

human polymorphonuclear leukocytes. M5005_Spy_1343 is predicted to encode a member of the LysR family of transcriptional regulators and is located upstream of a putative operon containing six genes. Five of these genes have sequence similarity to genes involved in short-chain fatty acid metabolism, whereas the sixth gene (luxS) is found in many bacterial species and is involved in quorum sensing. Unexpectedly, inactivation of the M5005_Spy_1343 gene resultedin hypervirulence in an intraperitoneal

Izabela Sitkiewicz, James M. Musser

Polish Journal of Microbiology , ISSUE 1, 17–24

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