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Review Paper | 04-December-2013

Effect of plant polyphenols on seizures – animal studies

and Discussion. A literature review was conducted using PubMed from 1963 to October 2013 relating effects of flavonoids on experimentally-induced seizures in rodents. Articles chosen for references were queried with the following prompts: “flavonoids and epilepsy”, “flavonoids and seizures”, “plant polyphenols and epilepsy”, and “plant polyphenols and seizures”. Out of 84 reports 32 pharmacological studies with chemically well-defined flavonoids and

Władysław Lasoń, Monika Leśkiewicz

Journal of Epileptology, Volume 21 , ISSUE 2, 79–87

Research Article | 21-May-2019

FRANCISELLA TULARENSIS – A DECEITFUL PATHOGEN

Francisella tularensis is an intracellular bacterial pathogen which causes a potentially lethal disease named tularemia. Some studies have been conducted to describe and identify the virulence factors of F. tularensis. This pathogen is able to infect a variety of cells of various hosts, including wild animals, especially rabbits, hares and rodents, and humans. This may suggest that genes of F. tularensis must adapt to many different intraorganismal environments. Still, little is known about the

Kamila Formińska, Aleksandra Anna Zasada

Postępy Mikrobiologii - Advancements of Microbiology, Volume 56 , ISSUE 2, 187–195

research-article | 07-July-2020

Anandamide in the anterior hypothalamus diminishes defensive responses elicited in mice threatened by Epicrates cenchria constrictor serpents

antagonist bicuculline to chemically stimulate the anterior (Falconi-Sobrinho and Coimbra, 2018), dorsomedial (Ullah et al., 2015; Biagioni et al., 2016), ventromedial (dos Anjos-Garcia et al., 2017; Ullah et al., 2017) and posterior (Biagioni et al., 2016; Falconi-Sobrinho et al., 2017a; 2017b) hypothalamus, in an attempt to correlate the different pattern of defensive behaviour responses (an NO-, NMDA- and bicuculline-induced panic attack-like effects) expressed by rodents with motivational states of

Tayllon dos Anjos-Garcia, Norberto Cysne Coimbra

Acta Neurobiologiae Experimentalis, Volume 80 , ISSUE 2, 179–191

research-article | 07-July-2020

Hypothermia in the course of acute traumatic spinal cord injury

differences (dogs, cats, non-human primates) often resulted in contradictory findings. This led to the standardization of experimental procedures and the use of laboratory rodents. Rats have become the most commonly used laboratory animals due to several similarities with humans in the pathophysiology and recovery processes experienced after traumatic SCI (Rosenzweig and McDonald, 2004). Despite the indisputable benefits of rat experiments, there are certain limits that have to be considered before

Jozef Kafka, Nadezda Lukacova, Igor Sulla, Marcela Maloveska, Zuzana Vikartovska, Dasa Cizkova

Acta Neurobiologiae Experimentalis, Volume 80 , ISSUE 2, 172–178

Review | 30-November-2020

Effects of cerebral hypoperfusion on the cerebral white matter: a meta-analysis

flow. Therefore, an experimental cerebral hypoperfused animal model is needed for understanding the association between CBF and WM alterations. In this systematic review, we aim to evaluate the association between cerebral hypoperfusion and WM changes in rodents by we meta-analyzed on published studies on the measurements of CBF and the total volume of WM in cerebral hypoperfusion model mice and aging mice. Systematic review, data collection and analysis This meta-analysis was conducted according

Juyeon Mun, Junyang Jung, Chan Park

Acta Neurobiologiae Experimentalis, Volume 81 , ISSUE 3, 295–306

Research paper | 15-January-2019

Acute cold allodynia induced by oxaliplatin is attenuated by amitriptyline

Oxaliplatin is a third-generation, platinum-based antitumor drug used to treat colorectal cancer. Since its main adverse effect is neuropathic pain resulting from chemotherapy-induced peripheral neuropathy (CIPN), this drug is used to study the neurobiology of CIPN in rodents and to search for analgesics that could attenuate neuropathic pain symptoms – cold and tactile allodynia that develop in most of the oxaliplatin-treated subjects. In this research, testing across various temperatures, we

Anna Furgała, Robert Sałat, Kinga Sałat

Acta Neurobiologiae Experimentalis, Volume 78 , ISSUE 4, 315–321

research-article | 30-November-2018

Alteration of oxidative stress markers and behavior of rats in a novel model of depression

to 45 kHz. These frequencies are in the range of normal vocalization of rodents, with frequencies of 20–25 kHz being associated with a negative “emotional state” in rats, as they are produced by animals during pain stimulation and defeat in a fight (Litvin et al., 2007). Vocalizations of 40–45 kHz are identified as being “emotionally positive” since they are associated with food stimulation and coitus in rats (Brudzynski et al., 2007). Different frequencies are given randomly, which prevents

Anna Gorlova, Dmitrii Pavlov, Eugene Zubkov, Yana Zorkina, Anatoly Inozemtsev, Anna Morozova, Vladimir Chekhonin

Acta Neurobiologiae Experimentalis, Volume 79 , ISSUE 3, 232–238

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