Marble burying is considered an, albeit controversial, animal model of the compulsive like behaviors of obsessive-compulsive disorder (OCD). Hallmark features of OCD patients are similarities and, more prominent, differences from anxiety disorders, e.g., the absence of sex differences and resistance to spontaneous remission. We report an experiment on marble burying by male and female C57/BL6/N mice. Animals were administered either the classic anxiolytic drug, diazepam, that targets the GABA
George T. Taylor,
Acta Neurobiologiae Experimentalis , ISSUE 3, 254–260
Scandinavian Journal of Child and Adolescent Psychiatry and Psychology , ISSUE 2, 55–65
Acta Neurobiologiae Experimentalis , ISSUE 2, 152–157
compared to controls. However, we did not observe any sex differences in the expression of oxytocin and arginine-vasopressin mRNA in these regions. Our findings show that testosterone enhancement in pregnancy could have long-lasting effects on oxytocin and arginine-vasopressin levels in the brain of adult animals, but lead to changes in behavioral aspects of coping strategies only in males.
Acta Neurobiologiae Experimentalis , ISSUE 3, 264–270
analysing sex differences, girls generally had a longer sleep duration than boys (21) on weekdays, weekends, and during vacation (6).
Although sleep plays an important role in mental health, there are still very few studies using validated questionnaires to examine the prevalence of poor sleep among Swedish adolescents. Most previous studies, including those on a large-scale basis that report high rates of sleep disturbance in adolescents, are based on single questions, e.g. those only assessing ‘‘time
Scandinavian Journal of Child and Adolescent Psychiatry and Psychology , 10–17